Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Nrf2 activators"'
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)
Plain english summary The Nrf2 pathway signifies one of the most significant cell defense procedures against exogenous or endogenous stressors. Certainly, by increasing the expression of several cytoprotective genes, the transcription factor Nrf2 can
Externí odkaz:
https://doaj.org/article/f67bcade9097433d8513da53a35211a1
Publikováno v:
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, Vol 24, Iss 5, Pp 634-639 (2021)
Coronavirus disease-19 (COVID-19) is a new member of the coronavirus family causing acute respiratory infection. Patients with COVID-19 have a higher risk of developing oxidative stress during this infection. Moreover, the virus induces ROS productio
Externí odkaz:
https://doaj.org/article/509c397bcd154a4a950dd61ccc4e336e
Autor:
Kit‐Kay Mak, Zhang Shiming, Dr. Ola Epemolu, Prof. Dr. Albena T. Dinkova‐Kostova, Dr. Geoffrey Wells, Dr. Irina G. Gazaryan, Dr. Raghavendra Sakirolla, Prof. Dr. Zulkefeli Mohd, Prof. Dr. Mallikarjuna Rao Pichika
Publikováno v:
ChemistryOpen, Vol 11, Iss 10, Pp n/a-n/a (2022)
Abstract This is the first study investigating the nuclear factor (erythroid‐derived 2)‐like 2 (NRF2) activity of compounds containing a new scaffold, tetrahydrobenzo[b]thiophene. Eighteen compounds were synthesised and confirmed their NRF2 activ
Externí odkaz:
https://doaj.org/article/3b58c0e2150c48848d2a62f4f7dd5ec1
Publikováno v:
Antioxidants, Vol 12, Iss 5, p 1094 (2023)
Glutathione (GSH) has special antioxidant properties due to its high intracellular concentration, ubiquity, and high reactivity towards electrophiles of the sulfhydryl group of its cysteine moiety. In most diseases where oxidative stress is thought t
Externí odkaz:
https://doaj.org/article/1587d6a8914147ba885e3511abd7bb2b
Autor:
Işın Çakır, Pauline Lining Pan, Colleen K Hadley, Abdulrahman El-Gamal, Amina Fadel, Dina Elsayegh, Omnia Mohamed, Nasser M Rizk, Masoud Ghamari-Langroudi
Publikováno v:
eLife, Vol 11 (2022)
The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress characterized by low-grade inf
Externí odkaz:
https://doaj.org/article/8ce80cd319cd4d978169c459a5b62f22
Publikováno v:
Infection and Drug Resistance, Vol Volume 13, Pp 1735-1741 (2020)
Chih-Yin Lin,1 Chun-An Yao2 1Department of Neurology, Chang Gung Memorial Hospital, Linkou 333, Taiwan; 2Department of Dermatology, Cathay General Hospital, Taipei, TaiwanCorrespondence: Chun-An YaoDepartment of Dermatology, Cathay General Hospital,
Externí odkaz:
https://doaj.org/article/c940997d0cba40a98cce242a9b96195a
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Diabetes mellitus (DM) is a highly prevalent chronic disease that is accompanied with serious complications, especially cardiac and vascular complications. Thus, there is an urgent need to identify new strategies to treat diabetic cardiac and vascula
Externí odkaz:
https://doaj.org/article/fd59090e98554886ace1a36555861d8c
Akademický článek
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Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101647- (2020)
Controlling inflammation is critical for preventing many diseases including cancer, autoimmune disorders and hypersensitivity reactions. NF-E2-related factor 2 (Nrf2) is a key transcription factor that controls the cellular antioxidant and cytoprotec
Externí odkaz:
https://doaj.org/article/d21f39a274004dafa0eff2779d138804
Akademický článek
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