Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nozomu Inamoto"'
Autor:
Hiroaki Naraba, Hitonobu Tomoike, Yoshihiro Kokubo, Akira Okayama, Nozomu Inamoto, Naomi Tago, Hideyuki Yamawaki, Naoharu Iwai
Publikováno v:
Circulation Journal. 69:138-142
Background Reproducibility of results is important for the validity of genetic association studies. Recently, 3 functional polymorphisms, G(-930)A in CYBA, T481S in CLCNKB, and E65K in KCNMB1, were reported to be associated with blood pressure (BP) s
Autor:
Yoshihiro Kokubo, Naomi Yasui, Hitonobu Tomoike, Keisuke Shioji, Naoharu Iwai, Naomi Tago, Nozomu Inamoto
Publikováno v:
Journal of Hypertension. 22:1119-1126
We performed association studies between 118 single-nucleotide polymorphisms (SNPs) of 22 candidate genes (or gene family) and hypertension in a Japanese population.The study population consisted of 1880 subjects representing the general population i
Autor:
Toshiyuki Miyata, Hiroaki Naraba, Masayoshi Yoshii, Yoichi Goto, Toshifumi Mannami, Naomi Tago, Junko Nishioka, Hiroshi Nonogi, Shunichi Miyazaki, Yuhei Kawano, Yoshikazu Miwa, Kei Kamide, Naoharu Iwai, Shin Takiuchi, Keisuke Shioji, Nozomu Inamoto, Yoshihiro Kokubo
Publikováno v:
Journal of Human Genetics. 49:141-147
To investigate the effects of polymorphisms in the ATP-binding cassette transporter A1 ( ABCA1) gene on the high-density lipoprotein cholesterol (HDL-C) level and the incidence of myocardial infarction (MI), we performed association studies. Sequence
Autor:
Takashi Asai, Nozomu Inamoto, Jun Ogata, Shunroku Baba, Tomohiro Katsuya, Yoshihiro Kokubo, Hitonobu Tomoike, Toshio Ogihara, Toshifumi Mannami
Publikováno v:
Stroke. 34:1628-1633
Background and Purpose— The association of the methylenetetrahydrofolate reductase gene ( MTHFR ) with carotid atherosclerosis remains inconsistent. This may be due to small sample size and inappropriate analysis. We investigated the association of
Autor:
Yuxiao Fu, Jun Ogata, Takashi Asai, Masayuki Fukuda, Tomohiro Katsuya, Toshifumi Mannami, Jitsuo Higaki, Kazuhiko Ishikawa, Shunroku Baba, Nozomu Inamoto, Toshio Ogihara
Publikováno v:
Journal of Hypertension. 20:2017-2021
The apolipoprotein epsilon 4 allele (APOE/epsilon 4) increases plasma cholesterol level and the risk for the late onset type of Alzheimer's disease. However, the correlation between hypertension and APOE/epsilon 4 has not yet been clarified. To exami
Autor:
Jitsuo Higaki, Nozomu Inamoto, Yoshiaki Taniyama, Yoshihiro Yanagitani, Tadahiko Nishii, Kazuo Yamada, Atsuhiro Otsuka, Norio Komai, Koichi Moriguchi, Masumi Shimizu, Toshio Ogihara, Mitsuru Ohishi, Masashi Ohkuro, Takashi Asai, Atsunori Okamura, Shin Takiuchi, Hiromi Rakugi
Publikováno v:
Journal of the American College of Cardiology. 37:719-725
OBJECTIVES We examined whether patients with ischemic heart disease (IHD) should be treated with nicorandil, an adenosine triphosphate-sensitive potassium channel opener, in addition to the regular use of nitrates. BACKGROUND It has been reported tha
Autor:
Yuxiao Fu, Hiromi Rakugi, Takashi Asai, Ken Sugimoto, Jitsuo Higaki, Yoshio Iwashima, Masayuki Fukuda, Toshio Ogihara, Nozomu Inamoto, Tomohiro Katsuya
Publikováno v:
Hypertension Research. 24:295-298
Predisposition to essential hypertension is associated with gene polymorphisms of the renin angiotensin system (RAS). Gene polymorphisms of the angiotensinogen and angiotensin converting enzyme genes are known to be risk factors for hypertension, whi
Autor:
Nozomu Inamoto, Kaori Yamaji, Norio Komai, Toshio Ogihara, Atsuhiro Otsuka, Koichi Kihara, Yoko Hatanaka, Misa Horio
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 35:691-694
We encountered an 80-year-old man with sudden bilateral visual disturbance. When he was admitted to the hospital, his blood pressure was 138/70 mmHg, and an ECG revealed atrial fibrillation. Neurological examination showed only bilateral homonymous h
Autor:
Kazuhiro Satomi, Yoshihiro Kokubo, Kiyotaka Matsuo, Takashi Noda, Takashi Kurita, Masazumi Akahoshi, Wataru Shimizu, Naohiko Aihara, Hitonobu Tomoike, Noritoshi Nagaya, Shiro Kamakura, Nozomu Inamoto, Kazuhiro Suyama
Publikováno v:
Journal of cardiovascular electrophysiology. 18(4)
Introduction: The clinical phenotype is 8 to 10 times more prevalent in males than in females in patients with Brugada syndrome. Brugada syndrome has been reported to be thinner than asymptomatic normal controls. We tested the hypothesis that higher
Autor:
Hitonobu Tomoike, Shin Takiuchi, Kei Kamide, Yuhei Kawano, Jin Yang, Hironori Hanada, Mariko Banno, Akira Okayama, Yoshihiro Kokubo, Nozomu Inamoto, Chihiro Tanaka, Toshiyuki Miyata
Publikováno v:
Journal of hypertension. 23(5)
Background Genome-wide scans from Italy and China suggest a hypertension-susceptible locus between D2S2278 (nucleotides 11 245 080–11 245 358) and D2S168 (nucleotides 11 467 214–11 467 422) on chromosome 2. Methods We performed a large associatio