Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nozomi Yachida"'
Autor:
Manako Yamaguchi, Hirofumi Nakaoka, Kazuaki Suda, Kosuke Yoshihara, Tatsuya Ishiguro, Nozomi Yachida, Kyota Saito, Haruka Ueda, Kentaro Sugino, Yutaro Mori, Kaoru Yamawaki, Ryo Tamura, Sundaramoorthy Revathidevi, Teiichi Motoyama, Kazuki Tainaka, Roel G. W. Verhaak, Ituro Inoue, Takayuki Enomoto
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Through regeneration, the endometrium accumulates somatic mutations that can lead to diseases like endometriosis and cancer. Here, the authors use genomics to analyse normal endometrial glands from different patient cohorts, detect rhizome structures
Externí odkaz:
https://doaj.org/article/489f82bf348f4647b67f1068544d1ba2
Autor:
Manako Yamaguchi, Kosuke Yoshihara, Kazuaki Suda, Hirofumi Nakaoka, Nozomi Yachida, Haruka Ueda, Kentaro Sugino, Yutaro Mori, Kaoru Yamawaki, Ryo Tamura, Tatsuya Ishiguro, Teiichi Motoyama, Yu Watanabe, Shujiro Okuda, Kazuki Tainaka, Takayuki Enomoto
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102258- (2021)
Summary: The fundamental morphology of the endometrial glands is not sufficiently understood by 2D observation because these glands have complicated winding and branching patterns. To construct a large picture of the endometrial gland structure, we p
Externí odkaz:
https://doaj.org/article/7a0f167e5ba6481493be0bab6e8baf10
Autor:
Haruka Ueda, Yutaro Mori, Kaoru Yamawaki, Tatsuya Ishiguro, Hirokazu Ohata, Ai Sato, Kentaro Sugino, Nozomi Yachida, Manako Yamaguchi, Kazuaki Suda, Ryo Tamura, Kosuke Yoshihara, Koji Okamoto, Takayuki Enomoto
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100354- (2021)
Summary: Advanced-stage gynecologic cancer remains a life-threatening disease. Here, we present a protocol for establishment of stable in vitro 3D spheroid cells derived from human uterine endometrial and ovarian cancer tissues. The tumor-derived sph
Externí odkaz:
https://doaj.org/article/4665d3b1ba904c53990469fedabe9087
Autor:
Ryo Tamura, Hirofumi Nakaoka, Nozomi Yachida, Haruka Ueda, Tatsuya Ishiguro, Teiichi Motoyama, Ituro Inoue, Takayuki Enomoto, Kosuke Yoshihara
Publikováno v:
Cancer Science. 114:2145-2157
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99f54125012aae9b13a438c95800e63
https://doi.org/10.1111/cas.15754
https://doi.org/10.1111/cas.15754
Autor:
Shujiro Okuda, Kosuke Yoshihara, Koji Matsuo, Ai Miyoshi, Kentaro Sugino, Hirofumi Nakaoka, Yutaka Ueda, Teiichi Motoyama, Akira Kikuchi, Yutaro Mori, Manako Yamaguchi, Ryo Tamura, Tatsuya Ishiguro, Kazuaki Suda, Nozomi Yachida, Ituro Inoue, Takayuki Enomoto, Kotaro Takahashi
Publikováno v:
Gynecologic Oncology. 163:327-333
Background Although ovarian clear cell carcinoma (CCC) is associated with high incidence of thromboembolism, the clinicopathological and biological significance of hypercoagulable status in CCC remains unclear. Materials and methods We retrospectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ea902c3aceb08d4efda888f656423a
https://doi.org/10.1016/j.ygyno.2021.08.009
https://doi.org/10.1016/j.ygyno.2021.08.009
Autor:
Kaoru Yamawaki, Hiroaki Kase, Yutaro Mori, Kosuke Yoshihara, Kentaro Sugino, Manako Yamaguchi, Tatsuya Ishiguro, Kazuaki Suda, Hirofumi Nakaoka, Ryo Tamura, Nozomi Yachida, Teiichi Motoyama, Takayuki Enomoto, Haruka Ueda
Publikováno v:
Cancer Science
KRAS is the most frequently mutated in ovarian endometriosis. However, it is unclear whether the KRAS mutant allele's mRNA is expressed and plays a biological role in ovarian endometriosis. Here, we performed mutation‐specific RNA in situ hybridiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db79de7ebea2ee3787e7c18cd8cd85f
https://doi.org/10.1111/cas.14871
https://doi.org/10.1111/cas.14871
Autor:
Kentaro Sugino, Kaoru Yamawaki, Nozomi Yachida, Hirokazu Ohata, Kosuke Yoshihara, Koji Okamoto, Tatsuya Ishiguro, Kazuaki Suda, Manako Yamaguchi, Haruka Ueda, Yutaro Mori, Ryo Tamura, Takayuki Enomoto, Ai Sato
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 1, Pp 100354-(2021)
STAR Protocols, Vol 2, Iss 1, Pp 100354-(2021)
Summary Advanced-stage gynecologic cancer remains a life-threatening disease. Here, we present a protocol for establishment of stable in vitro 3D spheroid cells derived from human uterine endometrial and ovarian cancer tissues. The tumor-derived sphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e913a453659334ff209b17ae2634fb
http://europepmc.org/articles/PMC7905465
http://europepmc.org/articles/PMC7905465
Autor:
Shujiro Okuda, Manako Yamaguchi, Tatsuya Ishiguro, Kazuaki Suda, Hirofumi Nakaoka, Nozomi Yachida, Yutaro Mori, Teiichi Motoyama, Kazuki Tainaka, Yu Watanabe, Haruka Ueda, Kentaro Sugino, Kosuke Yoshihara, Kaoru Yamawaki, Takayuki Enomoto, Ryo Tamura
Publikováno v:
iScience
iScience, Vol 24, Iss 4, Pp 102258-(2021)
iScience, Vol 24, Iss 4, Pp 102258-(2021)
Summary The fundamental morphology of the endometrial glands is not sufficiently understood by 2D observation because these glands have complicated winding and branching patterns. To construct a large picture of the endometrial gland structure, we pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9e1657a741a9c3f1dd1bce09de2f1e
https://doi.org/10.1101/2020.05.29.118034
https://doi.org/10.1101/2020.05.29.118034
Autor:
Masanori Isobe, Kaoru Yamawaki, Takayuki Enomoto, Ituro Inoue, Ryo Tamura, Manako Yamaguchi, Kosuke Yoshihara, Yutaro Mori, Haruka Ueda, Hirofumi Nakaoka, Teiichi Motoyama, Kentaro Sugino, Tatsuya Ishiguro, Kazuaki Suda, Nozomi Yachida
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
ARID1A loss-of-function mutation accompanied by a loss of ARID1A protein expression is considered one of the most important driver events in endometriosis-associated ovarian cancer. Although our recent genomic study clarified that ARID1A loss-of-func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857d47bcd3e31a7d96dc1784d984a14f
https://pubmed.ncbi.nlm.nih.gov/32868822
https://pubmed.ncbi.nlm.nih.gov/32868822
Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis
Autor:
Kosuke Yoshihara, Takayuki Enomoto, Ituro Inoue, Luis Antonio Cruz Diaz, Hirofumi Nakaoka, Teiichi Motoyama, Kazuaki Suda, Nozomi Yachida
Publikováno v:
Cancer Science
Clear cell carcinoma of the ovary is thought to arise from endometriosis. In addition, retrograde menstruation of shed endometrium is considered the origin of endometriosis. However, little evidence supports cellular continuity from uterine endometri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023344f18f41fb2362d4ed5ac8bc766
https://pubmed.ncbi.nlm.nih.gov/32473611
https://pubmed.ncbi.nlm.nih.gov/32473611