Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Nozomi Nishimura"'
Autor:
Seth Lieberman, Daniel A. Rivera, Ryan Morton, Amrit Hingorani, Teresa L. Southard, Lynn Johnson, Jennifer Reukauf, Ryan E. Radwanski, Mingrui Zhao, Nozomi Nishimura, Oliver Bracko, Theodore H. Schwartz, Chris B. Schaffer
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract In partial onset epilepsy, seizures arise focally in the brain and often propagate. Patients frequently become refractory to medical management, leaving neurosurgery, which can cause neurologic deficits, as a primary treatment. In the cortex
Externí odkaz:
https://doaj.org/article/d22684f893044b91ac604fc32f314fdc
Autor:
Luye An, Dahihm Kim, Leanne R. Donahue, Menansili Abraham Mejooli, Chi-Yong Eom, Nozomi Nishimura, Andrew C. White
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Vitiligo is an autoimmune skin disease caused by cutaneous melanocyte loss. Although phototherapy and T cell suppression therapy have been widely used to induce epidermal re-pigmentation, full pigmentation recovery is rarely achieved due to
Externí odkaz:
https://doaj.org/article/eb02cc32c1ff4d63a42479f825e79c80
Autor:
Tomohiro Otani, Nozomi Nishimura, Hiroshi Yamashita, Satoshi Ii, Shigeki Yamada, Yoshiyuki Watanabe, Marie Oshima, Shigeo Wada
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 9, p e1011452 (2023)
The cerebral arterial network covering the brain cortex has multiscale anastomosis structures with sparse intermediate anastomoses (O[102] μm in diameter) and dense pial networks (O[101] μm in diameter). Recent studies indicate that collateral bloo
Externí odkaz:
https://doaj.org/article/3f0f40f3b65b4952955d1f616cbafc12
Airway epithelial STAT3 inhibits allergic inflammation via upregulation of stearoyl-CoA desaturase 1
Autor:
Nozomi Nishimura, Masaya Yokota, Shunjiro Kurihara, Arifumi Iwata, Takahiro Kageyama, Takashi Ito, Aiko Saku, Yuko Maezawa, Koichi Hirose, Hiroshi Nakajima
Publikováno v:
Allergology International, Vol 71, Iss 4, Pp 520-527 (2022)
Background: Airway epithelial cells (AECs) play a crucial role in the induction and development of allergic inflammation through the development and activation of immune cells, including Th2 cells and ILC2s. Recent studies have revealed that STAT3 ex
Externí odkaz:
https://doaj.org/article/39768381b74d45f98cf8788bfb27d962
Autor:
Tingting Zhang, Huan Du, Mariela Nunez Santos, Xiaochun Wu, Mitchell D. Pagan, Lianne Jillian Trigiani, Nozomi Nishimura, Thomas Reinheckel, Fenghua Hu
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Haploinsufficiency of progranulin (PGRN) is a leading cause of frontotemporal lobar degeneration (FTLD). PGRN is comprised of 7.5 granulin repeats and is processed into individual granulin peptides in the lysosome. However, very l
Externí odkaz:
https://doaj.org/article/63dfd99a4a9848ad96214c257ffd37aa
Autor:
Oliver Bracko, Lindsay K. Vinarcsik, Jean C. Cruz Hernández, Nancy E. Ruiz-Uribe, Mohammad Haft-Javaherian, Kaja Falkenhain, Egle M. Ramanauskaite, Muhammad Ali, Aditi Mohapatra, Madisen A. Swallow, Brendah N. Njiru, Victorine Muse, Pietro E. Michelucci, Nozomi Nishimura, Chris B. Schaffer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Obesity is linked to increased risk for and severity of Alzheimer’s disease (AD). Cerebral blood flow (CBF) reductions are an early feature of AD and are also linked to obesity. We recently showed that non-flowing capillaries, caused by ad
Externí odkaz:
https://doaj.org/article/e9f076f1a1ac4a1ca9d345e6325e1739
Autor:
Nikolai Rakhilin, Aliesha Garrett, Chi-Yong Eom, Katherine Ramos Chavez, David M. Small, Andrea R. Daniel, Melanie M. Kaelberer, Menansili A. Mejooli, Qiang Huang, Shengli Ding, David G. Kirsch, Diego V. Bohórquez, Nozomi Nishimura, Bradley B. Barth, Xiling Shen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Performing intravital imaging of the colon in mouse models is challenging due to the colon’s anatomic location and motility. Here, the authors develop a murine colonic window for intravital chronic imaging that maximises long-term animal survival a
Externí odkaz:
https://doaj.org/article/4870e24dd7e84d5da10cc08b011dd0cb
Autor:
Frank K Lee, Jane C Lee, Bo Shui, Shaun Reining, Megan Jibilian, David M Small, Jason S Jones, Nathaniel H Allan-Rahill, Michael RE Lamont, Megan A Rizzo, Sendoa Tajada, Manuel F Navedo, Luis Fernando Santana, Nozomi Nishimura, Michael I Kotlikoff
Publikováno v:
eLife, Vol 10 (2021)
Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. However, the combination of these optical tools in
Externí odkaz:
https://doaj.org/article/1b8cb82950fd45838080d740449051eb
Autor:
Manami Kato, Kei Ikeda, Takahiro Sugiyama, Shigeru Tanaka, Kazuma Iida, Kensuke Suga, Nozomi Nishimura, Norihiro Mimura, Tadamichi Kasuya, Takashi Kumagai, Hiroki Furuya, Taro Iwamoto, Arifumi Iwata, Shunsuke Furuta, Akira Suto, Kotaro Suzuki, Eiryo Kawakami, Hiroshi Nakajima
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0252116 (2021)
ObjectivesWe aimed to explore the associations of musculoskeletal inflammation patterns with peripheral blood innate lymphoid cell (ILC) populations, serum cytokines/chemokines, and treatment response to methotrexate in patients with rheumatoid arthr
Externí odkaz:
https://doaj.org/article/a39af186c627418fb57e583bfabdf9e7
Autor:
Nathaniel H. Allan-Rahill, Michael R. E. Lamont, William M. Chilian, Nozomi Nishimura, David M. Small
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cardiovascular disease is the leading cause of worldwide mortality. Intravital microscopy has provided unprecedented insight into leukocyte biology by enabling the visualization of dynamic responses within living organ systems at the cell-scale. The
Externí odkaz:
https://doaj.org/article/1a4b440a40e042eeafa9cad2a59f75eb