Výsledky vyhledávání - "Nozomi Nagano"

Akademický článek

A novel corpus of molecular to higher-order events that facilitates the understanding of the pathogenic mechanisms of idiopathic pulmonary fibrosis

Autor: Nozomi Nagano, Narumi Tokunaga, Masami Ikeda, Hiroko Inoura, Duong A. Khoa, Makoto Miwa, Mohammad G. Sohrab, Goran Topić, Mari Nogami-Itoh, Hiroya Takamura

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-24 (2023)

Abstract Idiopathic pulmonary fibrosis (IPF) is a severe and progressive chronic fibrosing interstitial lung disease with causes that have remained unclear to date. Development of effective treatments will require elucidation of the detailed pathogen

Externí odkaz: https://doaj.org/article/9bcee370ca6342a7a2d45ba137ad257c

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Akademický článek

Prediction of detailed enzyme functions and identification of specificity determining residues by random forests.

Autor: Chioko Nagao, Nozomi Nagano, Kenji Mizuguchi

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e84623 (2014)

Determining enzyme functions is essential for a thorough understanding of cellular processes. Although many prediction methods have been developed, it remains a significant challenge to predict enzyme functions at the fourth-digit level of the Enzyme

Externí odkaz: https://doaj.org/article/70f14435166c48d88131aa6ae073cfb4

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Akademický článek

MIDDAS-M: motif-independent de novo detection of secondary metabolite gene clusters through the integration of genome sequencing and transcriptome data.

Autor: Myco Umemura, Hideaki Koike, Nozomi Nagano, Tomoko Ishii, Jin Kawano, Noriko Yamane, Ikuko Kozone, Katsuhisa Horimoto, Kazuo Shin-ya, Kiyoshi Asai, Jiujiang Yu, Joan W Bennett, Masayuki Machida

Publikováno v: PLoS ONE, Vol 8, Iss 12, p e84028 (2013)

Many bioactive natural products are produced as "secondary metabolites" by plants, bacteria, and fungi. During the middle of the 20th century, several secondary metabolites from fungi revolutionized the pharmaceutical industry, for example, penicilli

Externí odkaz: https://doaj.org/article/9e08be6951244d86b9b07cbead749857

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Effectiveness of Nurse-Led Interventions for the Prevention of Mental Health Issues in Patients Leaving Intensive Care: A Systematic Review

Autor: Junpei Haruna, Takeshi Unoki, Nozomi Nagano, Shigeko Kamishima, Tomoki Kuribara

Publikováno v: Healthcare. 10:1716

This study aimed to evaluate the effectiveness of nurse-led interventions for the prevention of mental health disorders after intensive care unit discharge through a systematic review of the literature. The searches were conducted in the MEDLINE (via

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b77d522d89a27b49d7fe724eaa7246
https://doi.org/10.3390/healthcare10091716

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Using Bregmann Divergence Regularized Machine for Comparison of Molecular Local Structures

Autor: Tsuyoshi Kato, Raissa Relator, Nozomi Nagano

Publikováno v: IEICE Transactions on Information and Systems. :275-278

Although many 3D structures have been solved for proteins to date, functions of some proteins remain unknown. To predict protein functions, comparison of local structures of proteins with predefined model structures, whose functions have been elucida

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e645d01c1f1745cd44d43c2e4410205
https://doi.org/10.1587/transinf.2015edl8104

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EzCatDB: the enzyme reaction database, 2015 update

Autor: Nozomi Nagano, Naoko Nakayama, Takuo Doi, Kentaro Tomii, Masaru Fukuie, Kiyonobu Yokota, Kazuyoshi Ikeda, Tsuyoshi Kato

Publikováno v: Nucleic Acids Research

The EzCatDB database (http://ezcatdb.cbrc.jp/EzCatDB/) has emphasized manual classification of enzyme reactions from the viewpoints of enzyme active-site structures and their catalytic mechanisms based on literature information, amino acid sequences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4520dc7be35517d6e5781f1ab7d7cfd
https://doi.org/10.1093/nar/gku946

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Unveiling the Biosynthetic Pathway of the Ribosomally Synthesized and Post-translationally Modified Peptide Ustiloxin B in Filamentous Fungi

Autor: Nozomi Nagano, Ying Ye, Myco Umemura, Masayuki Machida, Teppei Kawahara, Hideaki Oikawa, Katsuya Gomi, Yuya Igarashi, Kazuo Shin-ya, Miho Izumikawa, Atsushi Minami

Publikováno v: Angewandte Chemie (International ed. in English). 55(28)

The biosynthetic machinery of the first fungal ribosomally synthesized and post-translationally modified peptide (RiPP) ustiloxin B was elucidated through a series of gene inactivation and heterologous expression studies. The results confirmed an ess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c25c3c40422616bf6334b1e74be7088
https://pubmed.ncbi.nlm.nih.gov/27166860

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Relationships between functional subclasses and information contained in active-site and ligand-binding residues in diverse superfamilies

Autor: Kenji Mizuguchi, Nozomi Nagano, Chioko Nagao

Publikováno v: Proteins: Structure, Function, and Bioinformatics. 78:2369-2384

To investigate the relationships between functional subclasses and sequence and structural information contained in the active-site and ligand-binding residues (LBRs), we performed a detailed analysis of seven diverse enzyme superfamilies: aldolase c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187720ddcb5440dfb0394b24e2a425fa
https://doi.org/10.1002/prot.22750

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Mechanism of translation based on intersubunit complementarities of ribosomal RNAs and tRNAs

Autor: Kozo Nagano, Nozomi Nagano

Publikováno v: Journal of Theoretical Biology. 245:644-668

A universal rule is found about nucleotide sequence complementarities between the regions 2653-2666 in the GTPase-binding site of 23S rRNA and 1064-1077 of 16S rRNA as well as between the region 1103-1107 of 16S rRNA and GUUCG (or GUUCA) of tRNAs. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea760b6ef061b8af809756502600d76
https://doi.org/10.1016/j.jtbi.2006.11.004

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Key challenges for the creation and maintenance of specialist protein resources

Publikováno v: Proteins-Structure, Function and Bioinformatics
Proteins-Structure, Function and Bioinformatics, Wiley, 2015, 83 (6), pp.1005-1013. ⟨10.1002/prot.24803⟩
Proteins-Structure Function and Bioinformatics, 83, 6, pp. 1005-13
Proteins, Vol. 83, No 6 (2015) pp. 1005-13
Proteins-Structure Function and Bioinformatics, 83, 1005-13
Proteins-Structure, Function and Bioinformatics, 2015, 83 (6), pp.1005-1013. ⟨10.1002/prot.24803⟩
Proteins

Contains fulltext : 153246.pdf (Publisher’s version ) (Open Access) As the volume of data relating to proteins increases, researchers rely more and more on the analysis of published data, thus increasing the importance of good access to these data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0515f893032d9841460c3036adc82a7
https://hal.archives-ouvertes.fr/hal-01438998

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