Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Noyko Stanilov"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 1009 (2024)
Cancer remains one of the leading causes of morbidity and mortality worldwide, necessitating continuous efforts to develop effective therapeutic strategies. Over the years, advancements in our understanding of the complex interplay between the immune
Externí odkaz:
https://doaj.org/article/03e3690adc2d481388b410b75052d9cf
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201775 (2018)
It is widely known that sporadic colorectal cancer (CRC) is age-related diseases with higher incidence rate among men. Transforming growth factor-β1 (TGF-β1) is a major immune regulatory cytokine with a great impact and dual role in gastrointestina
Externí odkaz:
https://doaj.org/article/4123cb7da39c49d4830bac52a0fd431c
Publikováno v:
World Journal of Gastrointestinal Oncology
BACKGROUND The role of transforming growth factor beta (TGF-β) signaling, including both the cytokine and their receptors, in the etiology of colorectal cancer (CRC) has been of particular interest lately. AIM To investigate the association between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7702f74b62e15c8fb252b84f6f5cec0e
https://doi.org/10.4251/wjgo.v13.i11.1766
https://doi.org/10.4251/wjgo.v13.i11.1766
Publikováno v:
Cancer microenvironment : official journal of the International Cancer Microenvironment Society. 10(1-3)
T helper 17 (Th17) and T regulatory (Treg) cytokines appear to be contributing greatly to colorectal cancer (CRC) development and progression. The aim of the current study was to investigate the expression of Foxp3; IL10; TGFB1; IL17A; IL6 and NOS2 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d7f4bafca16f04e0b673a0c315adeb
https://pubmed.ncbi.nlm.nih.gov/28868572
https://pubmed.ncbi.nlm.nih.gov/28868572
Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development
Publikováno v:
Molecular Biology Reports. 41:8099-8106
The insulin-like growth factor (IGF) system plays a prominent role in the cancer development. The IGF-1 receptor (IGF-1R) and its associated signalling pathway is an important growth regulatory pathway that has been impli- cated in colorectal carcino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d2ef730fa95d4b8293dca2f9dcd7a5
https://doi.org/10.1007/s11033-014-3708-2
https://doi.org/10.1007/s11033-014-3708-2
Publikováno v:
APMIS. 122:1223-1229
Colorectal cancer (CRC) patients were previously shown to express a signature of cytokines that contribute to cancer pathogenesis and are detectable in serum. The aim of this study was to evaluate the potential clinical use of circulating cytokine me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6e28b357d1b50f1e2f25a44ba473ed
https://doi.org/10.1111/apm.12288
https://doi.org/10.1111/apm.12288
Autor:
Zlatka Georgieva Dobreva, Jovcho P. Jovchev, Spaska Stanilova, Geo Cirovski, Lyuba Miteva, Noyko Stanilov
Publikováno v:
Molecular Biology Reports. 39:10895-10902
The main regulator of anti-tumor immune response is the activity of monocytes, suggesting that the produced cytokines may have a prognostic role. This study investigates gene expression of interleukin (IL)-12-related cytokine and IL-10 in stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e5d02c801f106b9be2b609815d03f6
https://doi.org/10.1007/s11033-012-1987-z
https://doi.org/10.1007/s11033-012-1987-z
Publikováno v:
Biotechnology & Biotechnological Equipment. 26:107-110
Many studies have shown that TNF-α is critically involved in tumor promotion and progression. We examined the ability of monocytes from patients with colorectal cancer in different stages of the disease to produce TNF-α after stimulation and the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01d5dc3b9b6361867dd5a243d37a6081
https://doi.org/10.5504/50yrtimb.2011.0020
https://doi.org/10.5504/50yrtimb.2011.0020
Autor:
Zlatka Georgieva Dobreva, Jovcho P. Jovchev, Spaska Stanilova, Iliya Karakolev, Lyuba Miteva, Noyko Stanilov
Publikováno v:
Biotechnology & Biotechnological Equipment. 26:89-95
The IGF-1R signalling pathway can positively regulate cell-cycle progression and thus play a critical role in cancer development. Although recent studies provide sufficient evidence supporting the ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c8956afe64d52da2c346a6bc4706f3
https://doi.org/10.5504/50yrtimb.2011.0017
https://doi.org/10.5504/50yrtimb.2011.0017
Publikováno v:
European Journal of Surgical Oncology (EJSO). 43:S7-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::806414faecc46ad0b1393bed21c971b3
https://doi.org/10.1016/j.ejso.2017.01.041
https://doi.org/10.1016/j.ejso.2017.01.041