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of 117
pro vyhledávání: '"Nowshin N"'
Autor:
Melanie Manetsch, Md Mostafizur Rahman, Brijeshkumar S Patel, Emma E Ramsay, Nowshin N Rumzhum, Hatem Alkhouri, Qi Ge, Alaina J Ammit
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59635 (2013)
Mitogen-activated protein kinase phosphatase 1 (MKP-1) represses MAPK-driven signalling and plays an important anti-inflammatory role in asthma and airway remodelling. Although MKP-1 is corticosteroid-responsive and increased by cAMP-mediated signall
Externí odkaz:
https://doaj.org/article/49fde66458a4423a8d7bf12640ac086c
Publikováno v:
In Pulmonary Pharmacology & Therapeutics April 2018 49:75-87
Publikováno v:
Journal of Cellular Physiology. 234:11070-11077
Prostaglandin E2 (PGE2 ) is a key prostanoid known to have both proinflammatory and anti-inflammatory impact in the context of chronic respiratory diseases. We hypothesize that these opposing effects may be the result of different prostanoid E (EP) r
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 49:75-87
Arachidonic acid is metabolized by cyclooxygenases (COX-1 and COX-2) into various prostanoids which exert different functions in mammalian physiology. One of these prostanoids, prostaglandin E 2 (PGE2 ), interacts with four different G protein-couple
Akademický článek
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Publikováno v:
Environmental Systems Research, Vol 12, Iss 1, Pp 1-17 (2023)
Abstract Urban sprawl is a global phenomenon that has resulted in a substantial impact on ecosystem services. This study assessed how land use changes have affected the ecosystem services in Dhaka and Gazipur districts, two important economic centers
Externí odkaz:
https://doaj.org/article/5185b415aab0412194f5e553a477efc9
Autor:
Alaina J. Ammit, Nowshin N. Rumzhum
Publikováno v:
European Journal of Pharmacology. 782:1-5
Prostaglandin E2 (PGE2) is a prostanoid with diverse actions in health and disease. In chronic respiratory diseases driven by inflammation, PGE2 has both positive and negative effects. An enhanced understanding of the receptor-mediated cellular signa
Autor:
Alaina J. Ammit, Nowshin N. Rumzhum
Publikováno v:
Clinical & Experimental Allergy. 46:397-410
© 2016 John Wiley & Sons Ltd. Cyclooxygenase 2 (COX-2: official gene symbol - PTGS2) has long been regarded as playing a pivotal role in the pathogenesis of airway inflammation in respiratory diseases including asthma. COX-2 can be rapidly and robus
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:128-135
Tachyphylaxis of the β2-adrenergic receptor limits the efficacy of bronchodilatory β2-agonists in respiratory disease. Cellular studies in airway smooth muscle (ASM) have shown that inflammatory mediators and infectious stimuli reduce β2-adrenergi
Publikováno v:
Journal of cellular physiology. 234(7)
Prostaglandin E