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Akademický článek
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Autor:
Nowak, Jakub Stanislaw
Many cellular functions depend on the tightly regulated expression of various proteins. Canonical control of the protein expression is associated with transcriptional regulation. However, the small non-coding RNAs called microRNAs (miRNAs) were ident
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.705372
Autor:
Nowak, Jakub Stanislaw, Mehn, Dora, Nativo, Paola, García, César Pascual, Gioria, Sabrina, Ojea-Jiménez, Isaac, Gilliland, Douglas, Rossi, François
Publikováno v:
In Toxicology Letters 3 January 2014 224(1):84-92
Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively
Autor:
Nowak, Jakub Stanislaw, Hobor, Fruzsina, Downie Ruiz Velasco, Angela, Choudhury, Nila Roy, Heikel, Gregory, Kerr, Alastair, Ramos, Andres, Michlewski, Gracjan
Lin28a inhibits the biogenesis of let-7 miRNAs by triggering the polyuridylation and degradation of their precursors by terminal uridylyltransferases TUT4/7 and 3'-5' exoribonuclease Dis3l2, respectively. Previously, we showed that Lin28a also contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d5e353e6424af87dabf9e07c6af311b
https://europepmc.org/articles/PMC5311490/
https://europepmc.org/articles/PMC5311490/
Lin28a uses distinct mechanisms of binding to RNA and affects positively and negatively miRNA levels
Autor:
Hobor, Fruzsina, Nowak, Jakub Stanislaw, Velasco, Angela, Choudhurry, Nila, Heikel, Gregory, Kerr, Alastair, Ramos, Andres, Michlewski, Gracjan
Publikováno v:
Hobor, F, Nowak, J S, Velasco, A, Choudhurry, N, Heikel, G, Kerr, A, Ramos, A & Michlewski, G 2017, ' Lin28a uses distinct mechanisms of binding to RNA and affects positively and negatively miRNA levels ', RNA . https://doi.org/10.1261/rna.059196.116
Lin28a inhibits the biogenesis of let-7 miRNAs by triggering the polyuridylation and degradation of their precursors by terminal uridylyltransferases TUT4/7 and 3’-5’ exoribonuclease Dis3l2, respectively. Previously, we showed that Lin28a also co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3094::a49efd4ca9ba29577a72a5aa03807bd3
https://www.pure.ed.ac.uk/ws/files/29246290/Lin28a_uses_distinct_mechanisms_of_binding_to_RNA_and_affects_positively_and_negatively_miRNA_levels.pdf
https://www.pure.ed.ac.uk/ws/files/29246290/Lin28a_uses_distinct_mechanisms_of_binding_to_RNA_and_affects_positively_and_negatively_miRNA_levels.pdf
Akademický článek
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Autor:
Nowak JS; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom., Hobor F; Institute of Structural and Molecular Biology, University College London, London, WC1E 6XA, United Kingdom., Downie Ruiz Velasco A; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom., Choudhury NR; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom., Heikel G; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom., Kerr A; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom., Ramos A; Institute of Structural and Molecular Biology, University College London, London, WC1E 6XA, United Kingdom., Michlewski G; Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, United Kingdom.
Publikováno v:
RNA (New York, N.Y.) [RNA] 2017 Mar; Vol. 23 (3), pp. 317-332. Date of Electronic Publication: 2016 Nov 23.