Zobrazeno 1 - 10
of 1 954
pro vyhledávání: '"Novel gene"'
Autor:
Fuad Al Mutairi, Faisal Joueidi, Maha Alshalan, Essra Aloyouni, Mariam Ballow, Mohammed Aldrees, Abdulkareem Al Abdulrahman, Abeer Al Tuwaijri, Safdar Abbas, Muhammad Umair, Majid Alfadhel
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35361- (2024)
Background: HMGXB4 (additionally known as HMG2L1) is a non-histone DNA-binding protein that contains a single HMG-box domain. HMGXB4 was originally described in Xenopus where it was seen to negatively regulate the Wnt/β-catenin signaling pathway. Ma
Externí odkaz:
https://doaj.org/article/981d10349b2d4a7aa25dc99fabcd779c
Autor:
Yavuz Sahin, Jianming Pei, Don A. Baldwin, Nashwa Mansoor, Lori Koslosky, Peter Abdelmessieh, Y. Lynn Wang, Reza Nejati, Joseph. R. Testa
Publikováno v:
Leukemia Research Reports, Vol 21, Iss , Pp 100465- (2024)
Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy associated with various combinations of gene mutations, epigenetic abnormalities, and chromosome rearrangement-related gene fusions. Despite the significant degree of heterogene
Externí odkaz:
https://doaj.org/article/f0c3cc23a9b1481eaa5a4ec667934ac3
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
BackgroundLung squamous cell carcinoma (LUSC) is a devastating and difficult-to-treat type of lung cancer, and the prognosis of LUSC is the worst. The functional roles of focal adhesion-related genes were explored in LUSC based on data from The Cance
Externí odkaz:
https://doaj.org/article/da4e8fcb180844e89cbb6d033c093c7c
Autor:
Dorota Monies, Ewa Goljan, Rapid Exome Consortium, Mirna Assoum, Muna Albreacan, Faisal Binhumaid, Shazia Subhani, Abdulmlik Boureggah, Mais Hashem, Firdous Abdulwahab, Omar Abuyousef, Mohamad H. Temsah, Fahad Alsohime, James Kelaher, Mohamed Abouelhoda, Brian F. Meyer, Fowzan S. Alkuraya
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background The clinical utility of exome sequencing is now well documented. Rapid exome sequencing (RES) is more resource-intensive than regular exome sequencing and is typically employed in specialized clinical settings wherein urgent molec
Externí odkaz:
https://doaj.org/article/ee01add0ed534164b5ebc4a8df8103f8
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTPolydnaviruses (PDVs), obligatory symbionts with parasitoid wasps, function as host immune suppressors and growth and development regulator. PDVs can induce host haemocyte apoptosis, but the underlying mechanism remains largely unknown. Here,
Externí odkaz:
https://doaj.org/article/9b3072c6392242a39ddaa48fcd9823ff
Publikováno v:
National Science Open, Vol 2 (2023)
In recent decades, gene-editing technologies, typically based on deoxyribonucleases to specifically modify genomic sequences, have dramatically remodeled various aspects of life sciences, including fundamental research, breeding, and medical therapeu
Externí odkaz:
https://doaj.org/article/1a87e2cab37d40beb958a19cca20fee7
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Akademický článek
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Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 29, Iss , Pp 339-342 (2022)
ABSTRACT: Objectives: Human infection caused by an uncommon Salmonella enterica subsp. diarizonae (hereafter S. diarizonae) is rising. However, knowledge concerning S. diarizonae is still limited. This study aimed to investigate the genomic features
Externí odkaz:
https://doaj.org/article/de9826f404f441d284a29a22a8cd3f05