Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Novel Signaling Pathways in Immunometabolism and Obesity"'
Autor:
Martin G. Myers, Joel M. Cline, Erik S. Clutter, Anabel Flores, Lauren C. DeSantis, Alexander H Bedard, Christin Carter-Su, Abrielle M Cacciaglia, Lawrence S. Argetsinger, Jessica L. Cote
Publikováno v:
Journal of the Endocrine Society
The scaffold protein SH2B1 plays a critical role in the regulation of energy balance and glucose homeostasis—humans with mutations in SH2B1 are obese and diabetic, as are SH2B1KO mice. The 4 known isoforms of SH2B1 (α, β, γ, δ), which differ on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a681d5993a1572a0806c3be1a2c6f7
https://doi.org/10.1210/js.2019-or12-6
https://doi.org/10.1210/js.2019-or12-6
Publikováno v:
Journal of the Endocrine Society
Recent studies have shown that heterogeneity among adipocytes exists even within a single white adipose tissue (WAT) depot. Our lab has uncovered developmentally distinct subpopulations of WAT adipocytes that are distinguished by the expression of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a71d2a606f1d4fb4f1ddd2bdabf301
https://doi.org/10.1210/js.2019-or12-4
https://doi.org/10.1210/js.2019-or12-4
Publikováno v:
Journal of the Endocrine Society
Low-grade inflammation is responsible for many obesity-associated pathologies such as insulin resistance, type 2 diabetes and reduction in protective immunity. T cells play an important role in mounting an effective immune response and the modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a914cdaeaba58abbcd195da7cf8bf97
https://doi.org/10.1210/js.2019-or12-2
https://doi.org/10.1210/js.2019-or12-2
Autor:
Jesse Cochran
Publikováno v:
Journal of the Endocrine Society
Since the initial use of ketogenic diets (KD) as adjunctive treatment for epilepsy, these diets are being increasingly used to promote weight loss and to reduce the risk of metabolic sequelae of severe obesity. Typical KD are very low in carbohydrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb73c740da01c90409476df369800ad
https://doi.org/10.1210/js.2019-or12-5
https://doi.org/10.1210/js.2019-or12-5
Autor:
Zhenzhong Cui, Bradley Carlson, Hui Sun, Lee S. Weinstein, Oksana Gavrilova, Min Chen, Peter Metzger
Publikováno v:
Journal of the Endocrine Society
The central melanocortin α-MSH acts through MC4R receptors, which are known to activate Gsα/cAMP signaling, to promote negative energy balance by inhibiting food intake (FI) and stimulating energy expenditure (EE). However, we have shown that mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887fe56bcc3af52f0856a4cb5d58c787
http://europepmc.org/articles/PMC6554890
http://europepmc.org/articles/PMC6554890