Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Novel N Chegou"'
Autor:
Tara Carney, Jennifer A Rooney, Nandi Niemand, Bronwyn Myers, Danie Theron, Robin Wood, Laura F White, Christina S Meade, Novel N Chegou, Elizabeth Ragan, Gerhard Walzl, Robert Horsburgh, Robin M Warren, Karen R Jacobson
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0262440 (2022)
People who use illicit drugs (PWUDs) have been identified as a key at-risk group for tuberculosis (TB). Examination of illicit drug use networks has potential to assess the risk of TB exposure and disease progression. Research also is needed to asses
Externí odkaz:
https://doaj.org/article/d67302dd7a9e4497bb68d037fc11c7cc
Autor:
Jane Alexandra Shaw, Maynard Meiring, Tracy Cummins, Novel N Chegou, Conita Claassen, Nelita Du Plessis, Marika Flinn, Andriette Hiemstra, Léanie Kleynhans, Vinzeigh Leukes, Andre G Loxton, Candice MacDonald, Nosipho Mtala, Helmuth Reuter, Donald Simon, Kim Stanley, Gerard Tromp, Wolfgang Preiser, Stephanus T Malherbe, Gerhard Walzl
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247852 (2021)
BackgroundInequality is rife throughout South Africa. The first wave of COVID-19 may have affected people in lower socioeconomic groups worse than the affluent. The SARS-CoV-2 seroprevalence and the specificity of anti-SARS-CoV-2 antibody tests in So
Externí odkaz:
https://doaj.org/article/8592710943f34ee2bc18bdbe5e341ff5
Serum and cerebrospinal fluid host proteins indicate stroke in children with tuberculous meningitis.
Autor:
Charles M Manyelo, Novel N Chegou, James A Seddon, Candice I Snyders, Hygon Mutavhatsindi, Portia M Manngo, Gerhard Walzl, Kim Stanley, Regan S Solomons
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0250944 (2021)
IntroductionStroke is a common complication in children with tuberculous meningitis (TBM). Host proteins may give us insight into the mechanisms of stroke in TBM and serve as biomarkers for detection of stroke, however, they have not been widely expl
Externí odkaz:
https://doaj.org/article/a742ba5451b64bcb83bb927ce3772d44
Autor:
Ruschca Jacobs, Elizna Maasdorp, Stephanus Malherbe, Andre G Loxton, Kim Stanley, Gian van der Spuy, Gerhard Walzl, Novel N Chegou
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160546 (2016)
There is an urgent need for new tools for the early diagnosis of TB disease and monitoring of the response to treatment, especially in resource-constrained settings. We investigated the usefulness of host markers detected in saliva as candidate bioma
Externí odkaz:
https://doaj.org/article/dce091f951ce44489f8cca178393c578
Autor:
Willem J du Plessis, Léanie Kleynhans, Nelita du Plessis, Kim Stanley, Stephanus T Malherbe, Elizna Maasdorp, Katharina Ronacher, Novel N Chegou, Gerhard Walzl, Andre G Loxton
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152710 (2016)
Mycobacterium tuberculosis (M.tb) remains a successful pathogen, causing tuberculosis disease numbers to constantly increase. Although great progress has been made in delineating the disease, the host-pathogen interaction is incompletely described. B
Externí odkaz:
https://doaj.org/article/bb3f865476bf4f689afebb5da0923231
Autor:
Paulin N Essone, Novel N Chegou, Andre G Loxton, Kim Stanley, Magdalena Kriel, Gian van der Spuy, Kees L Franken, Tom H Ottenhoff, Gerhard Walzl
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102584 (2014)
BACKGROUND: We previously identified Mycobacterium tuberculosis (M.tb) antigen-induced host markers that showed promise as TB diagnostic candidates in 7-day whole blood culture supernatants. The aim of the present study was to evaluate the utility of
Externí odkaz:
https://doaj.org/article/458f59a62f4c443da9d238626a1ee5e3
Autor:
Novel N Chegou, Anne K Detjen, Lani Thiart, Elisabetta Walters, Anna M Mandalakas, Anneke C Hesseling, Gerhard Walzl
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64226 (2013)
BACKGROUND: The diagnosis of childhood tuberculosis (TB) disease remains a challenge especially in young and HIV-infected children. Recent studies have identified potential host markers which, when measured in Quantiferon (QFT-IT) supernatants, show
Externí odkaz:
https://doaj.org/article/d72bda9190284b6d86841ec473c7b3eb
Autor:
Jayne S Sutherland, Maeve K Lalor, Gillian F Black, Lyn R Ambrose, Andre G Loxton, Novel N Chegou, Desta Kassa, Adane Mihret, Rawleigh Howe, Harriet Mayanja-Kizza, Marie P Gomez, Simon Donkor, Kees Franken, Willem Hanekom, Michel R Klein, Shreemanta K Parida, W Henry Boom, Bonnie A Thiel, Amelia C Crampin, Martin Ota, Gerhard Walzl, Tom H M Ottenhoff, Hazel M Dockrell, Stefan H E Kaufmann, GCGH Biomarkers for TB consortium
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74080 (2013)
BACKGROUND:Tuberculosis (TB) remains a global health threat with 9 million new cases and 1.4 million deaths per year. In order to develop a protective vaccine, we need to define the antigens expressed by Mycobacterium tuberculosis (Mtb), which are re
Externí odkaz:
https://doaj.org/article/123f1077ef0d46748fd6f8db23b29b37
Autor:
Novel N Chegou, Paulin N Essone, Andre G Loxton, Kim Stanley, Gillian F Black, Gian D van der Spuy, Paul D van Helden, Kees L Franken, Shreemanta K Parida, Michel R Klein, Stefan H E Kaufmann, Tom H M Ottenhoff, Gerhard Walzl
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38501 (2012)
BACKGROUND: Recent interferon gamma (IFN-γ)-based studies have identified novel Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens as diagnostic candidates. In this study, the levels of 11 host markers other than IFN-γ, were evalu
Externí odkaz:
https://doaj.org/article/37149e2a1cd749c5846b30da5a5ae205
Publikováno v:
Biomarkers. :1-11