Zobrazeno 1 - 10
of 515
pro vyhledávání: '"Noveck RJ"'
Publikováno v:
Drug Design, Development and Therapy, Vol 2013, Iss default, Pp 619-625 (2013)
Robert J Noveck,1 Pamela S Douglas,2 Shein-Chung Chow,3 Barry Mangum,4 Shashidhar Kori,5 Donald J Kellerman51Duke Clinical Research Unit, Division of Clinical Pharmacology, Duke University School of Medicine, Durham, NC, USA; 2Imaging Program, Duke C
Externí odkaz:
https://doaj.org/article/486a01ad962041cb827eb6430389d329
Autor:
Burt, T1 talburtmd@gmail.com, Noveck, RJ2, MacLeod, DB3, Layton, AT4, Rowland, M5, Lappin, G6
Publikováno v:
CTS: Clinical & Translational Science. Sep2017, Vol. 10 Issue 5, p337-350. 14p.
Autor:
Burt, T, MacLeod, D, Lee, K, Santoro, A, DeMasi, DK, Hawk, T, Feinglos, M, Rowland, M, Noveck, RJ
Publikováno v:
Burt, T, MacLeod, D C, Lee, K, Santoro, A, Demasi, D K, Hawk, T, Feinglos, M, Rowland, M & Noveck, R J 2017, ' Intra-Target Microdosing-A Novel Drug Development Approach : Proof of Concept, Safety, and Feasibility Study in Humans ', Clinical and Translational Science . https://doi.org/10.1111/cts.12477
Clinical and Translational Science
Clinical and Translational Science
Intra-target microdosing (ITM) is a novel drug development approach aimed at increasing the efficiency of first-in-human (FIH) testing of new molecular entities (NMEs). ITM combines intra-target drug delivery and "microdosing," the subpharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::fb9bdacdfdf553dd1b41f0974baa6baf
https://doi.org/10.1111/cts.12477
https://doi.org/10.1111/cts.12477
Autor:
Audley J; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Gliniewicz EF; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zarember KA; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Hong HS; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Wald G; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Kuhns DB; Neutrophil Monitoring Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Kang E; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Malech HL; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Suffredini AF; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD, USA., Noveck RJ; Duke Clinical Research Unit, Duke University School of Medicine, Durham, NC, USA., Dinubile MJ; BioAegis Therapeutics, Inc., North Brunswick, NJ, USA., Levinson SL; BioAegis Therapeutics, Inc., North Brunswick, NJ, USA., Stossel TP; BioAegis Therapeutics, Inc., North Brunswick, NJ, USA., Gallin JI; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. jig@nih.gov.
Publikováno v:
Inflammation [Inflammation] 2021 Feb; Vol. 44 (1), pp. 270-277. Date of Electronic Publication: 2020 Sep 04.
Autor:
Van Eldik LJ; Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.; Spinal Cord and Brain Injury Research Center, University of Kentucky, Lexington, Kentucky, USA., Sawaki L; Department of Physical Medicine & Rehabilitation, University of Kentucky, Lexington, Kentucky, USA., Bowen K; Bluegrass Research Consultants, Inc., Versailles, Kentucky, USA., Laskowitz DT; Department of Neurology, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA., Noveck RJ; Duke Early Phase Clinical Research Unit, Durham, North Carolina, USA., Hauser B; Duke Early Phase Clinical Research Unit, Durham, North Carolina, USA., Jordan L; Duke Early Phase Clinical Research Unit, Durham, North Carolina, USA., Spears TG; Duke Clinical Research Institute, Durham, North Carolina, USA., Wu H; Duke Clinical Research Institute, Durham, North Carolina, USA., Watt K; Duke Clinical Research Institute, Durham, North Carolina, USA., Raja S; Department of Neurology, Duke University, Durham, North Carolina, USA.; Duke Early Phase Clinical Research Unit, Durham, North Carolina, USA., Roy SM; Department of Pharmacology, Northwestern University, Chicago, Illinois, USA., Watterson DM; Department of Pharmacology, Northwestern University, Chicago, Illinois, USA., Guptill JT; Department of Neurology, Duke University, Durham, North Carolina, USA.; Duke Clinical Research Institute, Durham, North Carolina, USA.; Duke Early Phase Clinical Research Unit, Durham, North Carolina, USA.
Publikováno v:
Clinical pharmacology in drug development [Clin Pharmacol Drug Dev] 2021 Feb; Vol. 10 (2), pp. 131-143. Date of Electronic Publication: 2020 Apr 07.
Autor:
Oo C; SunLife Biopharma, Morris Plains, NJ, 07950, USA. charlesoo@yahoo.com., Noveck RJ; Duke University Medical Center, Durham, NC, USA.
Publikováno v:
Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2020 Mar; Vol. 54 (2), pp. 444-446. Date of Electronic Publication: 2020 Jan 06.
Autor:
Ben Salem C; Clinical Pharmacology, Pharmacovigilance Center of Sousse, Faculty of Medicine of Sousse, University of Sousse, Street Mohamed Karoui, 4002, Sousse, Tunisia. bensalem.c@gmail.com., Agrebi M; Clinical Pharmacology, Pharmacovigilance Center of Sousse, Faculty of Medicine of Sousse, University of Sousse, Street Mohamed Karoui, 4002, Sousse, Tunisia., Sahnoun D; Clinical Pharmacology, Pharmacovigilance Center of Sousse, Faculty of Medicine of Sousse, University of Sousse, Street Mohamed Karoui, 4002, Sousse, Tunisia., Fathallah N; Clinical Pharmacology, Pharmacovigilance Center of Sousse, Faculty of Medicine of Sousse, University of Sousse, Street Mohamed Karoui, 4002, Sousse, Tunisia., Hmouda H; Intensive Care, Department of Intensive Care, Sahloul Hospital, University of Sousse, Sousse, Tunisia.
Publikováno v:
Drug safety [Drug Saf] 2024 Sep 17. Date of Electronic Publication: 2024 Sep 17.
Autor:
Cowart D; Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC, USA., Venuti RP; Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC, USA., Lynch K; Duke Early Phase Clinical Research Unit, Durham, NC, USA., Guptill JT; Duke Early Phase Clinical Research Unit, Durham, NC, USA., Noveck RJ; Duke Early Phase Clinical Research Unit, Durham, NC, USA., Foo SY; Cardioxyl Pharmaceuticals, Inc., Chapel Hill, NC, USA.
Publikováno v:
Journal of clinical pharmacology [J Clin Pharmacol] 2019 May; Vol. 59 (5), pp. 717-730. Date of Electronic Publication: 2019 Jan 31.
Publikováno v:
CTS: Clinical & Translational Science; Nov2017, Vol. 10 Issue 6, p470-479, 10p
Autor:
Burt, T, MacLeod, D, Lee, K, Santoro, A, DeMasi, DK, Hawk, T, Feinglos, M, Rowland, M, Noveck, RJ
Publikováno v:
CTS: Clinical & Translational Science; Sep2017, Vol. 10 Issue 5, p351-359, 9p