Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Noushin, Akhoundsadegh"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Pseudomonas aeruginosa and Staphylococcus aureus are often comorbid human pathogens, isolated from expectorated sputum of cystic fibrosis patients and chronically infected wounds. Prior studies revealed a competitive advantage of P. aerugino
Externí odkaz:
https://doaj.org/article/235809aaf0224cf2b9c9c6d6a0f984af
Autor:
Corrie R. Belanger, Melanie Dostert, Travis M. Blimkie, Amy Huei-Yi Lee, Bhavjinder Kaur Dhillon, Bing Catherine Wu, Noushin Akhoundsadegh, Negin Rahanjam, Javier Castillo-Arnemann, Reza Falsafi, Daniel Pletzer, Cara H. Haney, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Pseudomonas aeruginosa, like other pathogens, adapts to the limiting nutritional environment of the host by altering patterns of gene expression and utilizing alternative pathways required for survival. Understanding the genes essential for survival
Externí odkaz:
https://doaj.org/article/f18b987a41e34bd9aa29b6893415d7a8
Autor:
Bing (Catherine) Wu, Evan F. Haney, Noushin Akhoundsadegh, Daniel Pletzer, Michael J. Trimble, Alwin E. Adriaans, Peter H. Nibbering, Robert E. W. Hancock
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
Abstract Bacterial biofilms cause 65% of all human infections and are highly resistant to antibiotic therapy but lack specific treatments. To provide a human organoid model for studying host-microbe interplay and enabling screening for novel antibiof
Externí odkaz:
https://doaj.org/article/6edc97ff207d4c43ab33703f19b764a3
Autor:
Felix L. Santana, Karel Estrada, Morgan A. Alford, Bing C. Wu, Melanie Dostert, Lucas Pedraz, Noushin Akhoundsadegh, Pavneet Kalsi, Evan F. Haney, Suzana K. Straus, Gerardo Corzo, Robert E. W. Hancock
Publikováno v:
Antibiotics, Vol 11, Iss 11, p 1603 (2022)
Host defense peptides (HDPs) represent an alternative way to address the emergence of antibiotic resistance. Crocodylians are interesting species for the study of these molecules because of their potent immune system, which confers high resistance to
Externí odkaz:
https://doaj.org/article/d2e8b5659058444793f86ae59e3ca87f
Autor:
Bing (Catherine) Wu, Travis M. Blimkie, Evan F. Haney, Reza Falsafi, Noushin Akhoundsadegh, Robert E. W. Hancock
Publikováno v:
Cells, Vol 11, Iss 21, p 3459 (2022)
Bacterial biofilm infections associated with wounded skin are prevalent, recalcitrant, and in urgent need of treatments. Additionally, host responses in the skin to biofilm infections are not well understood. Here we employed a human organoid skin mo
Externí odkaz:
https://doaj.org/article/5e3c3ff83c4b40b5a3c4fb67cfc1dd6e
Autor:
Robert E. W. Hancock, Noushin Akhoundsadegh, Morgan A. Alford, Hashem Etayash, Matthew Drayton, Suzana K. Straus
Publikováno v:
Journal of medicinal chemistry. 64(22)
Effective anti-infective therapies are required to offset the rise in antibiotic resistance. A novel vancomycin-innate defense regulator conjugate (V-IDR1018) was constructed with multimodal functionality, including bacterial killing, biofilm eradica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2c577e50c26a5de40b073e822174d1
https://pubmed.ncbi.nlm.nih.gov/35048687
https://pubmed.ncbi.nlm.nih.gov/35048687
Autor:
Xiaojie Wang, Jianqiang Hao, Gigi Leung, Trisia Breitkopf, Eddy Wang, Nicole Kwong, Noushin Akhoundsadegh, Garth L. Warnock, Jerry Shapiro, Kevin J. McElwee
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Immunosuppressive drugs successfully prevent rejection of islet allografts in the treatment of type I diabetes. However, the drugs also suppress systemic immunity increasing the risk of opportunistic infection and cancer development in allograft reci
Externí odkaz:
https://doaj.org/article/4cb22f23293c48279275f5e3bad6cc09
Autor:
Hashem Etayash, Morgan Alford, Noushin Akhoundsadegh, Matthew Drayton, Suzana K. Straus, Robert E. W. Hancock
Publikováno v:
Journal of Medicinal Chemistry. 65:2710-2711
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::284440bc9d3732019bebde4aeff127ca
https://doi.org/10.1021/acs.jmedchem.1c02112
https://doi.org/10.1021/acs.jmedchem.1c02112
Autor:
Noushin Akhoundsadegh, Bing Catherine Wu, Evan F. Haney, Peter H. Nibbering, Daniel Pletzer, Michael J. Trimble, Robert E. W. Hancock, Alwin E Adriaans
Publikováno v:
NPJ Biofilms and Microbiomes
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
npj Biofilms and Microbiomes, 7(1). NATURE RESEARCH
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-13 (2021)
npj Biofilms and Microbiomes, 7(1). NATURE RESEARCH
Bacterial biofilms cause 65% of all human infections and are highly resistant to antibiotic therapy but lack specific treatments. To provide a human organoid model for studying host-microbe interplay and enabling screening for novel antibiofilm agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6605a983c257efdf568a3ce7a32c1181
https://doi.org/10.1038/s41522-020-00182-4
https://doi.org/10.1038/s41522-020-00182-4
Autor:
Eddy Wang, Katy Chong, Mei Yu, Noushin Akhoundsadegh, David J Granville, Jerry Shapiro, Kevin J McElwee
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62935 (2013)
Alopecia areata (AA) is a chronic autoimmune hair loss disease that affects several million men, women and children worldwide. Previous studies have suggested a link between autoimmunity, stress hormones, and increased cardiovascular disease risk. In
Externí odkaz:
https://doaj.org/article/85c55d5e32eb44a98b29671f5baa2a89