Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Noureddine Ben khalaf"'
Autor:
Cristina Skrypnyk, Aseel Ahmed Husain, Hisham Y. Hassan, Jameel Ahmed, Abdulla Darwish, Latifa Almusalam, Noureddine Ben Khalaf, Fahad Al Qashar
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Objective: Nemaline myopathies are a heterogeneous group of congenital myopathies caused by mutations in different genes associated with the structural and functional proteins of thin muscular filaments. Most patients have congenital onset characteri
Externí odkaz:
https://doaj.org/article/5f8d2ee2ea9640158f83f2bc0ccda58b
Autor:
Dana Ashoor, Maryam Marzouq, Khaled Trabelsi, Sadok Chlif, Nasser Abotalib, Noureddine Ben Khalaf, Ahmed R. Ramadan, M-Dahmani Fathallah
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
In this study, we evaluated the use of a predictive computational approach for SARS-CoV-2 genetic variations analysis in improving the current variant labeling system. First, we reviewed the basis of the system developed by the World Health Organizat
Externí odkaz:
https://doaj.org/article/3627a504ac0e47fe8843c24bba2ec17b
Autor:
Maryam Marzouq, Ali Nairouz, Noureddine Ben Khalaf, Sonia Bourguiba-Hachemi, Raed Quaddorah, Dana Ashoor, M. Dahmani Fathallah
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-8 (2021)
Abstract Objective This study aimed to identify novel genetic variants in the CR2 extracellular domain of the epidermal growth factor receptor (EGFR) in healthy individuals and patients with six different types of adenocarcinoma, in Arabian peninsula
Externí odkaz:
https://doaj.org/article/ceff5d58f79e410ab9966bf011c5084c
Autor:
Sana Ayari-Riabi, Noureddine Ben khalaf, Balkiss Bouhaouala-Zahar, Bernard Verrier, Thomas Trimaille, Zakaria Benlasfar, Mehdi Chenik, Mohamed Elayeb
Publikováno v:
Molecules, Vol 27, Iss 24, p 8677 (2022)
Leishmaniasis is the 3rd most challenging vector-borne disease after malaria and lymphatic filariasis. Currently, no vaccine candidate is approved or marketed against leishmaniasis due to difficulties in eliciting broad immune responses when using su
Externí odkaz:
https://doaj.org/article/de9a3f1023ba4a4482616e755d1f39c9
Autor:
Noureddine Ben Khalaf, Wedad Al-Mashoor, Azhar Saeed, Wassim Raslan, Halla Bakheit, Ameera Abdulhadi, Ammar Marouani, Safa Taha, Moiz Bakhiet, M. Dahmani Fathallah
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101100- (2021)
We previously reported Israa (immune-system-released activating agent), a novel gene nested in intron 6 of the mouse Zmiz1 gene. Zmiz1 is involved in several functions such as fertility and T cell development and its knockout leads to non-viable embr
Externí odkaz:
https://doaj.org/article/df0c09a5ac0442adb541266a47ce887d
Autor:
Dana Ashoor, Noureddine Ben Khalaf, Maryam Marzouq, Hamdi Jarjanazi, Sadok Chlif, M. Dahmani Fathallah
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
SARS-CoV-2 infectivity is largely determined by the virus Spike protein binding to the ACE2 receptor. Meanwhile, marked infection rate differences were reported between populations and individuals. To understand the disease dynamic, we developed a co
Externí odkaz:
https://doaj.org/article/4217f2d18bbd4a1095fb889f9153bbe1
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149612 (2016)
The interplay between the nervous and immune systems is gradually being unraveled. We previously reported in the mouse the novel soluble immune system factor ISRAA, whose activation in the spleen is central nervous system-dependent. We also showed th
Externí odkaz:
https://doaj.org/article/a8738e7014c54540b57754042ebf48cb
The network of molecular mediators involved in the transmigration of leukocytes to inflamed tissues has been expanding with the identification of new molecules involved in the inflammatory response. We have previously shown using a rat model that Pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab92b8231e08806a30011a2d727e9f21
https://doi.org/10.1101/2022.09.29.510069
https://doi.org/10.1101/2022.09.29.510069
Autor:
Giuseppe Romeo, Noureddine Ben Khalaf, Ivy Hurwitz, Douglas J Perkins, Loredana Salerno, Peter Sedillo, Susie Pham, Jessica Gonzales, Dahmani M. Fathallah, Sebastiano Intagliata, Valeria Pittalà, Sara Abdelghany
Publikováno v:
Journal of Computer-Aided Molecular Design. 35:297-314
Leishmaniasis is an infectious disease caused by parasites of the genus Leishmania and transmitted by the bite of a sand fly. To date, most available drugs for treatment are toxic and beyond the economic means of those affected by the disease. Protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5f9eacec83e410b0f86a963fe4b14f
https://doi.org/10.1007/s10822-021-00374-w
https://doi.org/10.1007/s10822-021-00374-w
Autor:
Lamiaa H. Al-Jamea, Alexander Woodman, Nihal M. Heiba, Shereen A. Elshazly, Noureddine Ben Khalaf, Fatimah S. Al-Yami, Khawaja Bilal Waheed, Abbas Al Mutair, Ahmad Alsedi, Jenifer V. Quiambao, Faisal M. Alzahrani, Walaa F. Albaqami, Faisal H. Al Qahtani, Nasser Mohammed Aljarah, Dahmani M. Fathallah, Abdel Halim Deifalla
Publikováno v:
Gene. 851
Iron-refractory iron deficiency anemia (IRIDA) is considered an autosomal recessive iron deficiency anemia due to mutations in the transmembrane protease serine 6 (TMPRSS6) gene. Variations in iron parameters and a higher risk of iron deficiency have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13109234e219b5eaa55ce724e1376fe3
https://pubmed.ncbi.nlm.nih.gov/36261087
https://pubmed.ncbi.nlm.nih.gov/36261087