Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Noura Tbeileh"'
Autor:
Noura Tbeileh, Luika Timmerman, Aras N Mattis, Kan Toriguchi, Yosuke Kasai, Carlos Corvera, Eric Nakakura, Kenzo Hirose, David B Donner, Robert S Warren, Eveliina Karelehto
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0271354 (2023)
Tumors rich in stroma are associated with advanced stage and poor prognosis in colorectal adenocarcinoma (CRC). Abundance of stromal cells also has implications for genomic analysis of patient tumors as it may prevent detection of somatic mutations.
Externí odkaz:
https://doaj.org/article/2dc4c0d3322847c3b3e3460295d2a39f
Publikováno v:
Bioinformatics. 38:3470-3473
Motivation Clustered mutations are found in the human germline as well as in the genomes of cancer and normal somatic cells. Clustered events can be imprinted by a multitude of mutational processes, and they have been implicated in both cancer evolut
Autor:
Noura Tbeileh, Ricardo J. Antonia, Aras N. Mattis, Luika A. Timmerman, Robert S. Warren, Carlos U. Corvera, Eveliina Karelehto, David B. Donner, Kan Toriguchi, Dania Annuar, Eric K. Nakakura, Kenzo Hirose
Publikováno v:
Journal of Clinical Oncology. 38:581-581
581 Background: Despite standard treatment with gemcitabine and cisplatin, median survival for unresectable Intrahepatic Cholangiocarcinoma (ICC) is < 1 year. Clearly, novel therapeutic strategies are urgently needed. The paucity of targetable mutati