Výsledky vyhledávání - "Noura F. Elmongy"

Regulation of NOX/p38 MAPK/PPARα pathways and miR-155 expression by boswellic acids reduces hepatic injury in experimentally-induced alcoholic liver disease mouse model: novel mechanistic insight

Autor: Rania M. Salama, Samah S. Abbas, Samar F. Darwish, Al Aliaa Sallam, Noura F. Elmongy, Sara A. El Wakeel

Publikováno v: Archives of Pharmacal Research. 46:323-338

Alcoholic liver disease (ALD) refers to hepatic ailments induced by excessive alcohol intake. The pathogenesis of ALD comprises a complex interplay between various mechanistic pathways, among which inflammation and oxidative stress are key players. B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e228462f74b7ae6ac0e6a0d454fd1a9
https://doi.org/10.1007/s12272-023-01441-6

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A novel protective role of sacubitril/valsartan in cyclophosphamide induced lung injury in rats: impact of miRNA-150-3p on NF-κB/MAPK signaling trajectories

Autor: Rehab A. Hasan, Manal L. Louka, Maggie M. Ramzy, Ghada A. Abdel-Latif, Mona F. Schaalan, Noura F. Elmongy, Azza H. Abd Elwahab

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports

Cyclophosphamide (CP) is a chemotherapeutic agent that induces oxidative stress causing multiple organ damage. Sacubitril/valsartan, is a combined formulation of neprilysin inhibitor (sacubitril) and angiotensin II receptor blocker (valsartan), that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a5e8ee3226757eb0f710cdba7bf7ac
http://link.springer.com/article/10.1038/s41598-020-69810-5

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Morus macroura Miq. Fruit extract protects against acetic acid-induced ulcerative colitis in rats: Novel mechanistic insights on its impact on miRNA-223 and on the TNFα/NFκB/NLRP3 inflammatory axis

Autor: Rania M. Salama, Samar F. Darwish, Ismail El Shaffei, Noura F. Elmongy, Nouran M. Fahmy, Manal S. Afifi, Ghada A. Abdel-Latif

Publikováno v: Food and Chemical Toxicology. 165:113146

Nod-like receptor pyrin domain-1 containing 3 (NLRP3) inflammasome/tumor necrosis factor alpha (TNFα)/nuclear factor kappa B (NFκB) inflammatory pathway is known to be involved in the pathogenesis of ulcerative colitis (UC). Inversely, miRNA-223 ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877b2fa7102d8880b6139401696be8a3
https://doi.org/10.1016/j.fct.2022.113146

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Protective effect of Morus macroura Miq. fruit extract against acetic acid-induced ulcerative colitis in rats: Involvement of miRNA-223 and TNFα/NFκB/NLRP3 inflammatory pathway

Autor: Noura F. Elmongy, Rania M. Salama, S. Darwish, I. El Shaffei, Ghada A. Abdel-Latif, M. Afifi

Tumor necrosis factor receptor (TNFR) activation and nuclear factor kappa B (NFκB) expression play a significant role in the activation of nod-like receptor pyrin domain-1 containing 3 (NLRP3) inflammasome inflammatory pathway, which is involved in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6b0b614ea76f6d39eb1c4fa977a65cd
https://doi.org/10.1101/2020.12.22.423927

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LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced testicular toxicity in rats: Role of neprilysin inhibition and lncRNA TUG1 in ameliorating apoptosis

Autor: Rania M. Salama, Mona F. Schaalan, Noura F. Elmongy, Azza H. Abd Elwahab, Mona Abd-Elgalil

Publikováno v: Toxicology. 437:152439

Cyclophosphamide (CP) is widely used as chemotherapy in various cancers; however, testicular atrophy has been encountered as an associated adverse effect. Oxidative stress, enhanced endoplasmic reticulum (ER) stress, and subsequent apoptosis are invo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7632e322440933770968c266cd84618d
https://doi.org/10.1016/j.tox.2020.152439

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