Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nour Shobaki"'
Autor:
Tijana Martinov, Kelly M. McKenna, Wei Hong Tan, Emily J. Collins, Allie R. Kehret, Jonathan D. Linton, Tayla M. Olsen, Nour Shobaki, Anthony Rongvaux
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Since the late 1980s, mice have been repopulated with human hematopoietic cells to study the fundamental biology of human hematopoiesis and immunity, as well as a broad range of human diseases in vivo. Multiple mouse recipient strains have been devel
Externí odkaz:
https://doaj.org/article/f7cfd8d34aea4a7d9978cbbce94b6642
Autor:
Samir N. Khleif, Seema Gupta, Mikayel Mkrtichyan, Mai-Britt Zocca, Ayako Wakatsuki Pedersen, Mads Hald Andersen, Nour Shobaki, Zainab Ramlaoui, Xingdong Yang, Veerupaxagouda Patil, Pankaj Gaur, Vivek Verma, Rahul Nandre
Supplementary Figure from IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0edd7ca342d91a9cef7de4a043847aee
https://doi.org/10.1158/2326-6066.22544379.v1
https://doi.org/10.1158/2326-6066.22544379.v1
Autor:
Samir N. Khleif, Seema Gupta, Mikayel Mkrtichyan, Mai-Britt Zocca, Ayako Wakatsuki Pedersen, Mads Hald Andersen, Nour Shobaki, Zainab Ramlaoui, Xingdong Yang, Veerupaxagouda Patil, Pankaj Gaur, Vivek Verma, Rahul Nandre
The immunosuppressive tumor microenvironment (TME) does not allow generation and expansion of antitumor effector cells. One of the potent immunosuppressive factors present in the TME is the indoleamine-pyrrole 2,3-dioxygenase (IDO) enzyme, produced m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ee05cf106a5bc42dc9b17ba076c0e8
https://doi.org/10.1158/2326-6066.c.6550626
https://doi.org/10.1158/2326-6066.c.6550626
Autor:
Rahul Nandre, Vivek Verma, Pankaj Gaur, Veerupaxagouda Patil, Xingdong Yang, Zainab Ramlaoui, Nour Shobaki, Mads Hald Andersen, Ayako Wakatsuki Pedersen, Mai-Britt Zocca, Mikayel Mkrtichyan, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Immunology Research. 10:571-580
The immunosuppressive tumor microenvironment (TME) does not allow generation and expansion of antitumor effector cells. One of the potent immunosuppressive factors present in the TME is the indoleamine-pyrrole 2,3-dioxygenase (IDO) enzyme, produced m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4a9bb2631cd48b13fafc2cf76179bb
https://doi.org/10.1158/2326-6066.cir-21-0457
https://doi.org/10.1158/2326-6066.cir-21-0457
Autor:
Wael Traboulsi, Subhadip Kundu, Pankaj Gaur, Zainab Ramlaoui, Dareen Sarhan, Nour Shobaki, Jacob Lee, Nazli Jafarzadeh, Simon T. Barry, Viia E. Valge-Archer, Vivek Verma, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Research. 83:LB339-LB339
Olaparib is the most widely studied third-generation PARP inhibitor (PARPi) in clinical practice with a significant clinical outcome in BRCA deficient tumors such as breast and ovarian cancers. However, innate and adaptive resistance in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d74ccffc53ef1961329e9c7e474a468
https://doi.org/10.1158/1538-7445.am2023-lb339
https://doi.org/10.1158/1538-7445.am2023-lb339
Autor:
Nazli Jafarzadeh, Pankaj Gaur, Dareen Sarhan, Nour Shobaki, Wael Traboulsi, Zainab Ramlaoui, Vivek Verma, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Research. 82:LB217-LB217
Growing evidence suggests that hypoxia is one of the most important phenomena of solid tumors that supports tumor progression as well as therapeutic resistance. When T cells infiltrate the tumor microenvironment (TME), they encounter hypoxia and, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18695cc0e031db25609415e920922496
https://doi.org/10.1158/1538-7445.am2022-lb217
https://doi.org/10.1158/1538-7445.am2022-lb217
Autor:
Nour Shobaki, Pankaj Gaur, Rahul Nadre, Vivek Verma, Peter Ordentlich, Lei Wang, Nazli Jafarzadeh, Wael Traboulsi, Mikayel Mkrtichyan, Seema Gupta, Samir N. Khleif
Publikováno v:
Cancer Research. 82:LB566-LB566
Histone/protein deacetylases (HDACs) are a class of enzymes that regulate gene expression and are involved in regulating the transcription process as well as regulating fundamental cellular processes such as proliferation, differentiation and develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f33969022cde9bbdd78a814abb015458
https://doi.org/10.1158/1538-7445.am2022-lb566
https://doi.org/10.1158/1538-7445.am2022-lb566
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 325
The tumor-microenvironment contains large numbers of tumor-associated macrophages (TAMs) which are largely M2 phenotypes and are involved in pro-tumorous functions. Targeting TAMs so as to manipulate them and to modify their functions could be a nove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7832bc9e321edc7b77d1e67b55d2053
https://pubmed.ncbi.nlm.nih.gov/32649972
https://pubmed.ncbi.nlm.nih.gov/32649972
Publikováno v:
International Journal of Nanomedicine
Nour Shobaki,* Yusuke Sato,* Hideyoshi Harashima Laboratory for Molecular Design of Pharmaceutics, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Hokkaido, Japan *These authors contributed equally to this work Introduction: The dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dbb1b01ec100f322fffdaf1f47112a0
https://pubmed.ncbi.nlm.nih.gov/30587967
https://pubmed.ncbi.nlm.nih.gov/30587967
Autor:
Mahmoud M. Abd Elwakil, Yasuhiro Kon, Hideyoshi Harashima, Yaser Hosny Ali Elewa, Ikramy A. Khalil, Kenji Kusumoto, Yusuke Sato, Nour Shobaki
Publikováno v:
Advanced Functional Materials. 29:1970121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::222afba46e0e17868ec74a8b0ac0a585
https://doi.org/10.1002/adfm.201970121
https://doi.org/10.1002/adfm.201970121