Výsledky vyhledávání - "Nour J, Abdulhay"

Akademický článek

Massively multiplex single-molecule oligonucleosome footprinting

Autor: Nour J Abdulhay, Colin P McNally, Laura J Hsieh, Sivakanthan Kasinathan, Aidan Keith, Laurel S Estes, Mehran Karimzadeh, Jason G Underwood, Hani Goodarzi, Geeta J Narlikar, Vijay Ramani

Publikováno v: eLife, Vol 9 (2020)

Our understanding of the beads-on-a-string arrangement of nucleosomes has been built largely on high-resolution sequence-agnostic imaging methods and sequence-resolved bulk biochemical techniques. To bridge the divide between these approaches, we pre

Externí odkaz: https://doaj.org/article/3694ff2de5284ae9a0d6610c16155ba7

Zobrazit plný text záznamu

Infantile Myelofibrosis and Myeloproliferation with CDC42 Dysfunction

Publikováno v: Journal of Clinical Immunology

Studies of genetic blood disorders have advanced our understanding of the intrinsic regulation of hematopoiesis. However, such genetic studies have only yielded limited insights into how interactions between hematopoietic cells and their microenviron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79866655865f066a6366d6919aeb3966
http://europepmc.org/articles/PMC7253386

Zobrazit plný text záznamu

Single-fiber nucleosome density shapes the regulatory output of a mammalian chromatin remodeling enzyme

Autor: Nour J Abdulhay, Laura J Hsieh, Colin P McNally, Mythili Ketavarapu, Sivakanthan Kasinathan, Arjun S Nanda, Megan S Ostrowski, Ke Wu, Camille M Moore, Hani Goodarzi, Geeta J Narlikar, Vijay Ramani

ATP-dependent chromatin remodelers regulate the DNA accessibility required of virtually all nuclear processes. Biochemical studies have provided insight into remodeler action at the nucleosome level, but how these findings translate to activity on ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76640ea4672deaa0e9d166d08ffb435a

Zobrazit plný text záznamu

At least two to tango: Choreographing chromatin through cooperative footprints

Autor: Vijay Ramani, Nour J Abdulhay

Publikováno v: Mol Cell

Enhancers harbor binding motifs that recruit transcription factors (TFs) for gene activation. While cooperative binding of TFs at enhancers is known to be critical for transcriptional activation of a handful of developmental enhancers, the extent of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89f20b4d3e5bfd6179e0c975f8ac4ab
https://pubmed.ncbi.nlm.nih.gov/33705711

Zobrazit plný text záznamu

Massively multiplex single-molecule oligonucleosome footprinting

Autor: Mehran Karimzadeh, Geeta J. Narlikar, Hani Goodarzi, Vijay Ramani, Sivakanthan Kasinathan, Jason G. Underwood, Colin P. McNally, Laurel S Estes, Laura J Hsieh, Aidan Keith, Nour J Abdulhay

Publikováno v: eLife, Vol 9 (2020)
eLife

These are the intermediate data used in "Massively multiplex single-molecule oligonucleosome footprinting", where the nonspecific adenine methyltransferase EcoGII was used to footprint accessible chromatin, and the methylation was then read using the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67fe0df5bc1f90379cae29bf0f821ca8
https://escholarship.org/uc/item/6877h0gs

Zobrazit plný text záznamu

Author response: Massively multiplex single-molecule oligonucleosome footprinting

Autor: Laura J Hsieh, Vijay Ramani, Colin P. McNally, Hani Goodarzi, Sivakanthan Kasinathan, Nour J Abdulhay, Mehran Karimzadeh, Geeta J. Narlikar, Jason G. Underwood, Aidan Keith, Laurel S Estes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9de503fe6eb0fd37744afac427f1fd83
https://doi.org/10.7554/elife.59404.sa2

Zobrazit plný text záznamu

Developmentally-faithful and effective human erythropoiesis in immunodeficient and Kit mutant mice

Autor: Nour J. Abdulhay, Roberto Chiarle, Sean K. McFarland, Claudia Fiorini, Jacob C. Ulirsch, Mathias Munschauer, Vijay G. Sankaran

Publikováno v: American Journal of Hematology. 92:E513-E519

Immunodeficient mouse models have been valuable for studies of human hematopoiesis, but high-fidelity recapitulation of erythropoiesis in most xenograft recipients remains elusive. Recently developed immunodeficient and Kit mutant mice, however, have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fa93d7b3072e06c21923b322ff1c8d5
https://doi.org/10.1002/ajh.24805

Zobrazit plný text záznamu

Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation

Studies of allelic variation underlying genetic blood disorders have provided important insights into human hematopoiesis. Most often, the identified pathogenic mutations result in loss-of-function or missense changes. However, assessing the pathogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23654e534b656285f62dc7904aebe6fd
https://doi.org/10.1084/jem.20181625

Zobrazit plný text záznamu

Policy and regulations in light of the human body as a ‘superorganism’ containing multiple, intertwined symbiotic relationships

Autor: Nour J. Abdulhay, Matthew Harker, William Parker, Chantal Villeneuve, Dillan Bono-Lunn

Publikováno v: Clinical Research and Regulatory Affairs. 33:39-48

The human body is now understood to exist as an ecosystem that includes an abundance of life, called the human biome. For purposes of understanding and treating disease, the biome of the human ‘superorganism’ can be divided into three parts: huma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d14d053a329635069041c6793bb97c5
https://doi.org/10.1080/10601333.2016.1210159

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání