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Autor:
Matthias Schiemann, Uwe K. Appelt, Tim Sparwasser, Ulrike Billmeier, Roland Lang, Stefan Wirtz, Stephen M. Keyse, Jurjen Tel, Sandra Muench, Faizal A. M. Raffi, Joerg Mages, Katrin Jozefowski, Carl G. Figdor, Hubertus Hochrein, Nour Alati, Katharina Lahl, Magdalena Niedzielska
Publikováno v:
Journal of Immunology, 195, 4, pp. 1753-62
Journal of Immunology, 195, 1753-62
Journal of Immunology, 195, 1753-62
Plasmacytoid dendritic cells (pDCs) efficiently produce large amounts of type I IFN in response to TLR7 and TLR9 ligands, whereas conventional DCs (cDCs) predominantly secrete high levels of the cytokines IL-10 and IL-12. The molecular basis underlyi