A novel recombinant papillomavirus genome enabling in vivo RNA interference reveals that YB-1, which interacts with the viral regulatory protein E2, is required for CRPV-induced tumor formation in vivo

Autor: Leiprecht, Natalie, Notz, Ekaterina, Schuetz, Johanna, Haedicke, Juliane, Stubenrauch, Frank, Iftner, Thomas

YB-1 is considered a negative prognostic marker for different types of cancer. Increased YB-1 protein levels in tumor cells indicate a worse prognosis. In a preceding study comparing the transcripts of CRPV-induced benign papillomas to mRNA levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c32af89ff1c74c78841231b106c5408d
https://europepmc.org/articles/PMC4065403/

A novel recombinant papillomavirus genome enabling in vivo RNA interference reveals that YB-1, which interacts with the viral regulatory protein E2, is required for CRPV-induced tumor formation in vivo.

Autor: Leiprecht N; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany., Notz E; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany., Schuetz J; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany., Haedicke J; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany., Stubenrauch F; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany., Iftner T; Medical Virology, Division of Experimental Virology, University Hospital Tübingen Germany.

Publikováno v: American journal of cancer research [Am J Cancer Res] 2014 May 26; Vol. 4 (3), pp. 222-33. Date of Electronic Publication: 2014 May 26 (Print Publication: 2014).