Multi-omic analysis identifies hypoalbuminemia as independent biomarker of poor outcome upon PD-1 blockade in metastatic melanoma.

Autor: Leek, Lindsay V. M.¹ (AUTHOR), Notohardjo, Jessica C. L.² (AUTHOR), de Joode, Karlijn³ (AUTHOR), Velker, Eline L.² (AUTHOR), Haanen, John B. A. G.¹ (AUTHOR), Suijkerbuijk, Karijn P. M.⁴ (AUTHOR), Aarts, Maureen J. B.⁵ (AUTHOR), de Groot, Jan Willem B.⁶ (AUTHOR), Kapiteijn, Ellen⁷ (AUTHOR), van den Berkmortel, Franchette W. P. J.⁸ (AUTHOR), Westgeest, Hans M.⁹ (AUTHOR), de Gruijl, Tanja D.² (AUTHOR), Retel, Valesca P.^10,11 (AUTHOR), Cuppen, Edwin^12,13 (AUTHOR), van der Veldt, Astrid A. M.³ (AUTHOR), Labots, Mariette² (AUTHOR), Voest, Emile E.¹ (AUTHOR), van de Haar, Joris¹ (AUTHOR) j.vd.haar@nki.nl, van den Eertwegh, Alfons J. M.² (AUTHOR) vandeneertwegh@amsterdamumc.nl

Publikováno v: Scientific Reports. 5/16/2024, Vol. 14 Issue 1, p1-11. 11p.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Local delivery of low-dose anti–CTLA-4 to the melanoma lymphatic basin leads to systemic Treg reduction and effector T cell activation.

Autor: van Pul, Kim M., Notohardjo, Jessica C. L., Fransen, Marieke F., Koster, Bas D., Stam, Anita G. M., Chondronasiou, Dafni, Lougheed, Sinéad M., Bakker, Joyce, Kandiah, Vinitha, van den Tol, M. Petrousjka, Jooss, Karin, Vuylsteke, Ronald J. C. L. M., van den Eertwegh, Alfons J. M., de Gruijl, Tanja D.

Publikováno v: Science Immunology; 2022, Vol. 7 Issue 73, p1-16, 16p