Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Notochord morphogenesis"'
Publikováno v:
Dev Biol
Protein phosphatases regulate a wide array of proteins through post-translational modification and are required for a plethora of intracellular events in eukaryotes. While some core components of the protein phosphatase complexes are well characteriz
Autor:
Dali Zhang, Chu-Xia Deng, Meng Xu, Liangjun Yin, Peng Liu, Hangang Chen, Juhui Qiu, Yangli Xie, Fengtao Luo, Xiaolan Du, Lin Chen, Ruobin Zhang, Zhenhong Ni, Liang Chen, Xianding Sun, Zuqiang Wang, Di Chen, Fangfang Li, Shuai Chen, Junlan Huang, Bo Chen, Siru Zhou, Yang Zhou, Haiyang Huang, Lingfei Luo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Congenital scoliosis (CS) is a complex genetic disorder characterized by vertebral malformations. The precise etiology of CS is not fully defined. Here, we identify that mutation in dual serine/threonine and tyrosine protein kinase (dstyk) lead to CS
Autor:
Liufang Jing, Michael P. Kelly, Julie E Speer, Jacob M. Buchowski, Marcos N. Barcellona, Munish C. Gupta, Lori A. Setton
Degeneration and aging of the nucleus pulposus (NP) of the intervertebral disc (IVD) is accompanied by alterations in NP cell phenotype marked by a shift towards a fibroblast-like, catabolic state. We have recently demonstrated an ability to manipula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4a585376f603335c586fbbdaf621ed
https://doi.org/10.1101/2021.03.05.434094
https://doi.org/10.1101/2021.03.05.434094
Publikováno v:
Developmental Dynamics. 245:547-557
The notochord is a structure common to all chordates, and the feature that the phylum Chordata has been named after. It is a rod-like mesodermal structure that runs the anterior-posterior length of the embryo, adjacent to the ventral neural tube. The
Akademický článek
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Autor:
Zhiren Wang
Publikováno v:
Journal of Physics: Conference Series. 1593:012014
Zebrafish serves as a model organism in morphogenesis studies in cell biology. One of the main difficulties of modeling a specific morphogenetic process come from the proper identification of its key features. To study the influence of geometric cons
Publikováno v:
Developmental Biology. 397:248-256
Fate mapping with single cell resolution has typically been confined to embryos with completely stereotyped development. The lineages giving rise to the 40 cells of the Ciona notochord are invariant, but the intercalation of those cells into a single
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The vertebrate embryo undergoes a series of dramatic morphological changes as the body extends to form the complete anterior-posterior axis during the somite-forming stages. The molecular mechanisms regulating these complex processes are still largel
The notochord is a midline structure common to all chordate animals; it provides mechanical and signaling cues for the developing embryo. In vertebrates, the notochord plays key functions during embryogenesis, being a source of developmental signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10afdf0951403e016570f7612fc8aeb8
http://hdl.handle.net/11577/3252787
http://hdl.handle.net/11577/3252787
Publikováno v:
Developmental Dynamics. 243:612-620
Background: In the simple ascidian chordate Ciona, the signaling pathways and gene regulatory networks giving rise to initial notochord induction are largely understood and the mechanisms of notochord morphogenesis are being systematically elucidated