Zobrazeno 1 - 10
of 1 081
pro vyhledávání: '"Notch Signalling"'
Autor:
Eike-Benjamin Braune, Felix Geist, Xiaojia Tang, Krishna Kalari, Judy Boughey, Liewei Wang, Roberto A. Leon-Ferre, Antonino B. D’Assoro, James N. Ingle, Matthew P. Goetz, Julian Kreis, Kang Wang, Theodoros Foukakis, Anita Seshire, Dirk Wienke, Urban Lendahl
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-22 (2024)
Abstract Background Dysregulated Notch signalling contributes to breast cancer development and progression, but validated tools to measure the level of Notch signalling in breast cancer subtypes and in response to systemic therapy are largely lacking
Externí odkaz:
https://doaj.org/article/f8003a5a92c14e34b1fab373cd274d48
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
Neurodegenerative diseases, particularly Alzheimer’s disease (AD), pose a significant challenge in ageing populations. Our current understanding indicates that the onset of toxic amyloid and tau protein pathologies initiates disease progression. Ho
Externí odkaz:
https://doaj.org/article/4791c3aadd314098b7376ba2ec646166
Autor:
F Javier DeHaro-Arbona, Charalambos Roussos, Sarah Baloul, Jonathan Townson, María J Gómez Lamarca, Sarah Bray
Publikováno v:
eLife, Vol 12 (2024)
Developmental programming involves the accurate conversion of signalling levels and dynamics to transcriptional outputs. The transcriptional relay in the Notch pathway relies on nuclear complexes containing the co-activator Mastermind (Mam). By track
Externí odkaz:
https://doaj.org/article/4781ed00b42d49d095b9dc5ba595b60c
Publikováno v:
Cells, Vol 13, Iss 14, p 1174 (2024)
Members of the LGD/CC2D1 protein family contain repeats of the family-defining DM14 domains. Via this domain, they interact with members of the CHMP family, which are essential for the ESCRT machinery-mediated formation of intraluminal vesicles durin
Externí odkaz:
https://doaj.org/article/9714bca95b6d4e25951858e917d1fa7c
Autor:
Abhimanyu Kumar Jha
Publikováno v:
Frontiers in Oral Health, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/5487389aa660444ebd8d75a215f61346
Autor:
Tetsuo Yasugi, Makoto Sato
Publikováno v:
Fly, Vol 16, Iss 1, Pp 24-36 (2022)
Notch signalling is a well-conserved signalling pathway that regulates cell fate through cell-cell communication. A typical feature of Notch signalling is ‘lateral inhibition’, whereby two neighbouring cells of equivalent state of differentiation
Externí odkaz:
https://doaj.org/article/9b43f51d35b6471dad48f373fd27a38e
Akademický článek
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Akademický článek
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Publikováno v:
Parasites & Vectors, Vol 15, Iss 1, Pp 1-15 (2022)
Abstract Background Encystation of the protoscoleces (PSCs) of Echinococcus granulosus is the main cause of secondary hydatid dissemination in the intermediate host. Extracellular vesicles (EVs) can transfer miRNAs into parasite cells to regulate mRN
Externí odkaz:
https://doaj.org/article/0fe1c7975bf74f4cb509f25e7d67da68
NONHSAT098487.2 protects cardiomyocytes from oxidative stress injury by regulating the Notch pathway
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17388- (2023)
Acute myocardial infarction has increasingly become a global health problem and is a primary cause of cardiovascular disease-related death. Although long noncoding RNAs have been reported to play an important role in various cardiovascular diseases,
Externí odkaz:
https://doaj.org/article/217f7a807cd94cc4a56d9de45e9ccc89