Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Notch/genetics"'
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 57(4):377-398
The Notch signaling pathway is a direct cell-cell communication system involved in a wide variety of biological processes, and its disruption is observed in several pathologies. The pathway is comprised of a ligand-expressing (sender) cell and a rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___01180::06a553a91877cd1f349646b9d239e9be
https://research.tue.nl/en/publications/47541967-74ca-4784-a41c-4a1264d6ec37
https://research.tue.nl/en/publications/47541967-74ca-4784-a41c-4a1264d6ec37
Autor:
Yao Meng, Sami Sanlidag, Sacha A. Jensen, Sean A. Burnap, Weston B. Struwe, Andreas H. Larsen, Xinyi Feng, Shruti Mittal, Mark S. P. Sansom, Cecilia Sahlgren, Penny A. Handford
Publikováno v:
Science Signaling, 15(755):eabo3507. American Association for the Advancement of Science (AAAS)
Meng, Y, Sanlidag, S, Jensen, S A, Burnap, S A, Struwe, W B, Larsen, A H, Feng, X, Mittal, S, Sansom, M S P, Sahlgren, C & Handford, P A 2022, ' An N-glycan on the C2 domain of JAGGED1 is important for Notch activation ', Science Signaling, vol. 15, no. 755, eabo3507 . https://doi.org/10.1126/scisignal.abo3507
Meng, Y, Sanlidag, S, Jensen, S A, Burnap, S A, Struwe, W B, Larsen, A H, Feng, X, Mittal, S, Sansom, M S P, Sahlgren, C & Handford, P A 2022, ' An N-glycan on the C2 domain of JAGGED1 is important for Notch activation ', Science Signaling, vol. 15, no. 755, eabo3507 . https://doi.org/10.1126/scisignal.abo3507
The canonical members of the Jagged/Serrate and Delta families of transmembrane ligands have an extracellular, amino-terminal C2 domain that binds to phospholipids and is required for optimal activation of the Notch receptor. Somatic mutations that c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac4c9efe42b092cdfc89289531844635
http://www.scopus.com/inward/record.url?scp=85139651605&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85139651605&partnerID=8YFLogxK
Publikováno v:
Critical reviews in biochemistry and molecular biology. 57(4)
The Notch signaling pathway is a direct cell-cell communication system involved in a wide variety of biological processes, and its disruption is observed in several pathologies. The pathway is comprised of a ligand-expressing (sender) cell and a rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d69b0716241b1edff7b2d3e6311d647
https://pubmed.ncbi.nlm.nih.gov/36048510
https://pubmed.ncbi.nlm.nih.gov/36048510
Autor:
Susanne Fleig, Tamar Kapanadze, Jeremiah Bernier-Latmani, Julia K. Lill, Tania Wyss, Jaba Gamrekelashvili, Dustin Kijas, Bin Liu, Anne M. Hüsing, Esther Bovay, Adan Chari Jirmo, Stephan Halle, Melanie Ricke-Hoch, Ralf H. Adams, Daniel R. Engel, Sibylle von Vietinghoff, Reinhold Förster, Denise Hilfiker-Kleiner, Hermann Haller, Tatiana V. Petrova, Florian P. Limbourg
Publikováno v:
Nature Communications 13(1), 2022 (2022). doi:10.1038/s41467-022-29701-x
Nature communications, vol. 13, no. 1, pp. 2022
Nature communications, vol. 13, no. 1, pp. 2022
Nature Communications 13(1), 2022 (2022). doi:10.1038/s41467-022-29701-x
Published by Nature Publishing Group UK, [London]
Published by Nature Publishing Group UK, [London]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28a6642249ffbfdd4e2ae43d1760d8b
https://www.ncbi.nlm.nih.gov/pubmed/35440634
https://www.ncbi.nlm.nih.gov/pubmed/35440634
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), Company of Biologists, 2019, 146 (3), pp.dev172148. ⟨10.1242/dev.172148⟩
Development (Cambridge, England), 2019, 146 (3), pp.dev172148. ⟨10.1242/dev.172148⟩
Development (Cambridge, England), Company of Biologists, 2019, 146 (3), pp.dev172148. ⟨10.1242/dev.172148⟩
Development (Cambridge, England), 2019, 146 (3), pp.dev172148. ⟨10.1242/dev.172148⟩
© 2019. Published by The Company of Biologists. All rights reserved.
Most cells in our body communicate during development and throughout life via Notch receptors and their ligands. Notch receptors relay information from the cell surface to the
Most cells in our body communicate during development and throughout life via Notch receptors and their ligands. Notch receptors relay information from the cell surface to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77e08ce392aa0aef7b93d2e5ed67b6d
https://hal-pasteur.archives-ouvertes.fr/pasteur-02348265
https://hal-pasteur.archives-ouvertes.fr/pasteur-02348265
Publikováno v:
Cardiovascular Research. 109(2):196-203
Hereditary haemorrhagic telangiectasia (HHT) is characterized by the development of arteriovenous malformations--enlarged shunts allowing arterial flow to bypass capillaries and enter directly into veins. HHT is caused by mutations in ALK1 or Endogli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od________83::f324b9836bcddf5eba7532506416dfba
https://doi.org/10.1093/cvr/cvv264
https://doi.org/10.1093/cvr/cvv264
Autor:
Seung-Hee Jo, Renato G. Panizzon, Paola Ostano, Dania Al Labban, G. Paolo Dotto, Massimo Bongiovanni, Chiara Saglietti
Publikováno v:
The Journal of clinical investigation, vol. 128, no. 6, pp. 2581-2599
Notch 1/2 genes play tumor-suppressing functions in squamous cell carcinoma (SCC), a very common malignancy in skin and internal organs. In contrast with Notch, we show that the transcription factor CSL (also known as RBP-Jκ), a key effector of cano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28345da224ab25046bd6de3b630f1fe
https://serval.unil.ch/notice/serval:BIB_64DFBBAE75C2
https://serval.unil.ch/notice/serval:BIB_64DFBBAE75C2
Publikováno v:
Cardiovascular Research. 109:196-203
Hereditary haemorrhagic telangiectasia (HHT) is characterized by the development of arteriovenous malformations--enlarged shunts allowing arterial flow to bypass capillaries and enter directly into veins. HHT is caused by mutations in ALK1 or Endogli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ae88876f5bcb73b2893a67b73a0649
https://doi.org/10.1093/cvr/cvv264
https://doi.org/10.1093/cvr/cvv264
Autor:
Veerle Baert, H. Joseph Yost, Nathalie Jurisch-Yaksi, Przemko Tylzanowski, Tim Raemaekers, Applonia Josephine Rose, Guy Froyen, Wendy Vermeire, Cammon B. Arrington, Huiqi Lu, Roel Vandepoel, Emre Yaksi, Daphne Verleyen, Wim Annaert, Pieter Baatsen, Sebastian Munck, Thomy de Ravel, Suzie J. Scales
Publikováno v:
The Journal of Cell Biology
Rer1p is an ER/cis-Golgi membrane protein that maintains ciliary length and function by reducing γ-secretase complex assembly and activity (thereby balancing Notch signaling) and increasing Foxj1a expression.
Cilia project from the surface of m
Cilia project from the surface of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0670771d5653c4e13cbdb72f0604ace
http://europepmc.org/articles/PMC3601348
http://europepmc.org/articles/PMC3601348
Autor:
Ingo Bothe, Susanne Dietrich
Publikováno v:
Bothe, I & Dietrich, S 2006, ' The molecular setup of the avian head mesoderm and its implication for craniofacial myogenesis ', Developmental Dynamics, vol. 235, no. 10, pp. 2845-60 . https://doi.org/10.1002/dvdy.20903
The head mesoderm is the mesodermal tissue on either side of the brain, from forebrain to hindbrain levels, and gives rise to the genuine head muscles. Its relatedness to the more posterior paraxial mesoderm, the somites, which generate the muscles o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::882fff84f94adeb4a3cefac1b663fbd6
https://doi.org/10.1002/dvdy.20903
https://doi.org/10.1002/dvdy.20903