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Formulation and characterization of microspheres loaded with imatinib for sustained delivery

Autor: Ramazani, F., Chen, W., Van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T., Hennink, W. E., Kok, R. J., Sub Drug delivery, Sub General Pharmaceutics, Sub Drug targeting, Pharmaceutics

Publikováno v: International journal of pharmaceutics, 482(1-2), 123-130. Elsevier
International Journal of Pharmaceutics, 482(1-2), 123. Elsevier bedrijfsinformatie b.v.

The aim of this study was the development of imatinib-loaded poly(d,l-lactide-co-glycolide) (PLGA) microspheres with high loading efficiency which can afford continuous release of imatinib over a prolonged period of time. Imatinib mesylate loaded PLG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e56a06c65f557ea376852f568c44c06
https://doi.org/10.1016/j.ijpharm.2015.01.043

Biocompatibility of poly(D,L-lactic-co-hydroxymethyl glycolic acid) microspheres after subcutaneous and subcapsular renal injection

Autor: Kazazi-Hyseni, F., Zandstra, J., Popa, E. R., Goldschmeding, R., Lathuile, A. A R, Veldhuis, G. J., Van Nostrum, C. F., Hennink, W. E., Kok, R. J., Sub Drug delivery, Pharmaceutics

Publikováno v: International Journal of Pharmaceutics, 482(1-2), 99. Elsevier bedrijfsinformatie b.v.
International Journal of Pharmaceutics, 482(1-2), 99. Elsevier
International Journal of Pharmaceutics, 482(1-2), 99-109. Elsevier Bedrijfsinformatie b.v.

Poly(D,L-lactic-co-hydroxymethyl glycolic acid) (PLHMGA) is a biodegradable copolymer with potential as a novel carrier in polymeric drug delivery systems. In this study, the biocompatibility of PLHMGA microspheres (PLHMGA-ms) was investigated both i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9584eb6a7764dc173e7cecef10c68cf
https://pubmed.ncbi.nlm.nih.gov/25497444

Photopolymerized Thermosensitive Poly(HPMAlactate)-PEG Based Hydrogels: Effect of Network Design on Mechanical Properties, Degradation and Release Behavior

Autor: Censi, Roberta, Vermonden, T., Deschout, H., Braeckmans, K., DI MARTINO, Piera, De Smedt, S., Van Nostrum, C. F., Hennink, W. E.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3707::1c12620b4f904c29e06ed396819cacc1
http://hdl.handle.net/11581/203224

Sunitinib microspheres based on [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers for ocular drug delivery

Autor: Ramazani, F., Hiemstra, C., Steendam, R., Kazazi-Hyseni, F., Van Nostrum, C. F., Storm, G., Kiessling, F., Lammers, T., Hennink, W. E., Kok, R. J., Sub Drug delivery, Dep Farmaceutische wetenschappen, UIPS - Utrecht Institute for Pharmaceutical Sciences, Sub General Pharmaceutics, Pharmaceutics

Publikováno v: European journal of pharmaceutics and biopharmaceutics, 95(Part B), 368-377. Elsevier
European Journal of Pharmaceutics and Biopharmaceutics, 95, 368. Elsevier

Sunitinib is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that blocks several angiogenesis related pathways. The aim of this study was to develop sunitinib-loaded polymeric microspheres that can be used as intravitreal formulation for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a163b46628532276b6d86f63b1c518
https://hdl.handle.net/1874/329467