Time-of-flight spectroscopy for laser-driven proton beam monitoring

Autor: Marvin Reimold, Stefan Assenbaum, Constantin Bernert, Elke Beyreuther, Florian-Emanuel Brack, Leonhard Karsch, Stephan D. Kraft, Florian Kroll, Markus Loeser, Alexej Nossula, Jörg Pawelke, Thomas Püschel, Hans-Peter Schlenvoigt, Ulrich Schramm, Marvin E. P. Umlandt, Karl Zeil, Tim Ziegler, Josefine Metzkes-Ng

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Application experiments with laser plasma-based accelerators (LPA) for protons have to cope with the inherent fluctuations of the proton source. This creates a demand for non-destructive and online spectral characterization of the proton pul

Externí odkaz: https://doaj.org/article/125ffd34f4544a12b9c3ce7f4d935c0f

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Tumor irradiation in mice with a laser-accelerated proton beam

Autor: Kroll, F., Brack, F.-E., Bernert, C., Bock, S., Bodenstein, E., Brüchner, K., Cowan, T., Gaus, L., Gebhardt, R., Helbig, U., Karsch, L., Kluge, T., Kraft, S., Krause, M., Leßmann, E., Masood, U., Meister, S., Metzkes-Ng, J., Nossula, A., Pawelke, J., Pietzsch, J., Püschel, T., Reimold, M., Rehwald, M., Richter, C., Schlenvoigt, H.-P., Schramm, U., Umlandt, M. E. P., Ziegler, T., Zeil, K., Beyreuther, E.

Publikováno v: Nature Physics 18(2022), 316-322
APS DPP, 18.10.2022, Spokane, USA

Recent oncological studies identified beneficial properties of radiation applied at ultra-high dose rates several orders of magnitude higher than the clinical standard of the order of Gy/min. Sources capable of providing these ultra-high dose rates a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::985b52d9e92eb51f66c510d035f32c9a
https://www.hzdr.de/publications/Publ-33044-1

Source Data: Tumour irradiation in mice with a laser-accelerated proton beam (Open Access)

Autor: Kroll, F., Brack, F.-E., Bernert, C., Bock, S., Bodenstein, E., Brüchner, K., Cowan, T., Gaus, L., Gebhardt, R., Helbig, U., Karsch, L., Kluge, T., Kraft, S., Krause, M., Leßmann, E., Masood, U., Meister, S., Metzkes-Ng, J., Nossula, A., Pawelke, J., Pietzsch, J., Püschel, T., Reimold, M., Rehwald, M., Richter, C., Schlenvoigt, H.-P., Schramm, U., Umlandt, M. E. P., Ziegler, T., Zeil, K., Beyreuther, E.

Publikováno v: Publication date: 2022-03-11 Open accessDOI: 10.14278/rodare.1128Versions: 10.14278/rodare.1477 | 10.14278/rodare.1476 | 10.14278/rodare.1129License: CC-BY-4.0

Source data for all figures of publication: "Tumor irradiation in mice with a laser-accelerated proton beam". The folder structure is adapted to match thefigures in the publication.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::3d1ad288d2cabb2b0f9242c68b952599
https://www.hzdr.de/publications/Publ-33047-1

First systematic in vivo tumor irradiation in mice with laser-accelerated and dose-homogenized proton beams from the Draco PW laser

Autor: Sebastian Meister, Florian Kroll, Marvin Reimold, Elisabeth Lessmann, Florian-Emanuel Brack, Josefine Metzkes-Ng, Ulrich Schramm, Jörg Pawelke, Karl Zeil, Kerstin Brüchner, Alexej Nossula, Leonhard Karsch, Stephan Kraft, Elisabeth Bodenstein, Marvin E. P. Umlandt, Elke Beyreuther, Jens Pietzsch

Publikováno v: Laser Acceleration of Electrons, Protons, and Ions VI.

After the rediscovery of the normal tissue sparing effect of high dose rate radiation, i.e. the so-called FLASH effect, by Favaudon et al. in 2014, research activities on this topic have been revived and are flourishing ever since. Yet, the exact bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a301dac3ad4f3f64453f4b9f53dda69a
https://doi.org/10.1117/12.2589523