Zobrazeno 1 - 10
of 860
pro vyhledávání: '"Nosratola D, Vaziri"'
Autor:
Hua Miao, Fei Liu, Yan-Ni Wang, Xiao-Yong Yu, Shougang Zhuang, Yan Guo, Nosratola D. Vaziri, Shi-Xing Ma, Wei Su, You-Quan Shang, Ming Gao, Jin-Hua Zhang, Li Zhang, Ying-Yong Zhao, Gang Cao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Accumulated evidence suggested that gut microbial dysbiosis interplayed with progressive chronic kidney disease (CKD). However, no available therapy is effective in suppressing progressive CKD. Here, using microbiomics in 480 participants in
Externí odkaz:
https://doaj.org/article/f0388e0061014d22b8856082a830360e
Autor:
Mahyar Khazaeli, Ane C. F. Nunes, Yitong Zhao, Mahziar Khazaali, John Prudente, Nosratola D. Vaziri, Bhupinder Singh, Wei Ling Lau
Publikováno v:
Pharmacology Research & Perspectives, Vol 11, Iss 2, Pp n/a-n/a (2023)
Abstract Tetrahydrocurcumin (THC), a principal metabolite of curcumin, was tested in a rat model of type 2 diabetes mellitus. THC was administered via daily oral gavage with the lipid carrier polyenylphosphatidylcholine (PPC) as add‐on therapy to l
Externí odkaz:
https://doaj.org/article/e23ec94dbcf0445981db928eb5c72125
Autor:
Samuel A. Headley, Donna J. Chapman, Michael J. Germain, Elizabeth E. Evans, Jasmin Hutchinson, Karen L. Madsen, Talat Alp Ikizler, Emily M. Miele, Kristyn Kirton, Elizabeth O’Neill, Allen Cornelius, Brian Martin, Bradley Nindl, Nosratola D. Vaziri
Publikováno v:
BMC Nephrology, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardiovascular disease (CVD
Externí odkaz:
https://doaj.org/article/b43235108788470d97b1e08ef039af1c
Autor:
Hui Zhao, Lin Chen, Tian Yang, Ya-Long Feng, Nosratola D. Vaziri, Bao-Li Liu, Qing-Quan Liu, Yan Guo, Ying-Yong Zhao
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract The aryl hydrocarbon receptor (AhR) is a well-known ligand-activated cytoplasmic transcription factor that contributes to cellular responses against environmental toxins and carcinogens. AhR is activated by a range of structurally diverse co
Externí odkaz:
https://doaj.org/article/520c99a0dcd64c8089b23be2ce982aca
Autor:
Dan-Qian Chen, Gang Cao, Hua Chen, Christos P. Argyopoulos, Hui Yu, Wei Su, Lin Chen, David C. Samuels, Shougang Zhuang, George P. Bayliss, Shilin Zhao, Xiao-Yong Yu, Nosratola D. Vaziri, Ming Wang, Dan Liu, Jia-Rong Mao, Shi-Xing Ma, Jin Zhao, Yuan Zhang, You-Quan Shang, Huining Kang, Fei Ye, Xiao-Hong Cheng, Xiang-Ri Li, Li Zhang, Mei-Xia Meng, Yan Guo, Ying-Yong Zhao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Accurate monitoring of chronic kidney disease (CKD) progression is essential for efficient disease management. Here Chen et al. identify five serum metabolites in patients with stage 1–5 CKD whose levels associate with disease progression, and find
Externí odkaz:
https://doaj.org/article/4a04997a433f49e4a807e4cf744638af
Autor:
Lin Chen, Dan-Qian Chen, Jing-Ru Liu, Jun Zhang, Nosratola D. Vaziri, Shougang Zhuang, Hua Chen, Ya-Long Feng, Yan Guo, Ying-Yong Zhao
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 3, Pp 1-18 (2019)
Chronic kidney disease: The contribution of gut bacteria An imbalance in gut bacteria contributes to kidney tissue scarring and declined kidney function. An international study led by Ying-Yong Zhao at Northwest University, Xi’an, China, analyzed t
Externí odkaz:
https://doaj.org/article/43565d2e8e68440ab83c82622a87044e
Polyporus Umbellatus Protects Against Renal Fibrosis by Regulating Intrarenal Fatty Acyl Metabolites
Autor:
Yan-Ni Wang, Xia-Qing Wu, Dan-Dan Zhang, He-He Hu, Jian-Ling Liu, Nosratola D. Vaziri, Yan Guo, Ying-Yong Zhao, Hua Miao
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Chronic renal failure (CRF) results in significant dyslipidemia and profound changes in lipid metabolism. Polyporus umbellatus (PPU) has been shown to prevent kidney injury and subsequent kidney fibrosis.Methods: Lipidomic analysis was pe
Externí odkaz:
https://doaj.org/article/349282b0ee394e41be30a55403960cad
Autor:
Hua Chen, Min-Chang Wang, Yuan-Yuan Chen, Lin Chen, Yan-Ni Wang, Nosratola D. Vaziri, Hua Miao, Ying-Yong Zhao
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 11 (2020)
Background: Increasing evidence suggests a link between the gut microbiome and various diseases including hypertension and chronic kidney disease (CKD). However, studies examining the efficacy of controlling blood pressure and inhibiting the renin–
Externí odkaz:
https://doaj.org/article/4865d7afed1541a7991cab34d451cc53
Autor:
Yuan-Yuan Chen, Dan-Qian Chen, Lin Chen, Jing-Ru Liu, Nosratola D. Vaziri, Yan Guo, Ying-Yong Zhao
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Dysbiosis represents changes in composition and structure of the gut microbiome community (microbiome), which may dictate the physiological phenotype (health or disease). Recent technological advances and efforts in metagenomic and metabolom
Externí odkaz:
https://doaj.org/article/2342319992aa407bbde5369d15c5ab9f
Autor:
Dan-Qian Chen, Gang Cao, Hua Chen, Dan Liu, Wei Su, Xiao-Yong Yu, Nosratola D. Vaziri, Xiu-Hua Liu, Xu Bai, Li Zhang, Ying-Yong Zhao
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 505-521 (2017)
Changes in plasma concentration of small organic metabolites could be due to their altered production or urinary excretion and changes in their urine concentration may be due to the changes in their filtered load, tubular reabsorption, and/or altered
Externí odkaz:
https://doaj.org/article/72f0c6e8dfa746d186c1885d2cf5f146