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The delivery of small interfering RNAs (siRNA) is an efficient method for gene silencing through the induction of RNA interference (RNAi). It critically relies, however, on efficient vehicles for siRNA formulation, for transfection in vitro as well a
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A major hurdle for exploring RNA interference (RNAi) in a therapeutic setting is still the issue of in vivo delivery of small RNA molecules (siRNAs). The chemical modification of polyethylenimines (PEIs) offers a particularly attractive avenue toward
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Autor:
Noske, Sandra, Karimov, Michael, Krüger, Martin, Lilli, Bettina, Ewe, Alexander, Aigner, Achim
Publikováno v:
In European Journal of Pharmaceutics and Biopharmaceutics June 2024 199
Autor:
Karimov, Michael, Schulz, Marion, Kahl, Tim, Noske, Sandra, Kubczak, Malgorzata, Gockel, Ines, Thieme, René, Büch, Thomas, Reinert, Anja, Ionov, Maksim, Bryszewska, Maria, Franke, Heike, Krügel, Ute, Ewe, Alexander, Aigner, Achim
Publikováno v:
In Nanomedicine: Nanotechnology, Biology, and Medicine August 2021 36
Akademický článek
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Akademický článek
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Autor:
Noske S; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, Leipzig University, Faculty of Medicine, 04107 Leipzig, Germany., Karimov M; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, Leipzig University, Faculty of Medicine, 04107 Leipzig, Germany., Aigner A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, Leipzig University, Faculty of Medicine, 04107 Leipzig, Germany., Ewe A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Clinical Pharmacology, Leipzig University, Faculty of Medicine, 04107 Leipzig, Germany.
Publikováno v:
Nanomaterials (Basel, Switzerland) [Nanomaterials (Basel)] 2020 Sep 10; Vol. 10 (9). Date of Electronic Publication: 2020 Sep 10.
Autor:
Ewe A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Faculty of Medicine, Clinical Pharmacology, Leipzig University, 04107 Leipzig, Germany., Noske S; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Faculty of Medicine, Clinical Pharmacology, Leipzig University, 04107 Leipzig, Germany.; Faculty of Chemistry, Technical University Kaiserslautern, 67663 Kaiserslautern, Germany., Karimov M; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Faculty of Medicine, Clinical Pharmacology, Leipzig University, 04107 Leipzig, Germany., Aigner A; Rudolf-Boehm-Institute for Pharmacology and Toxicology, Faculty of Medicine, Clinical Pharmacology, Leipzig University, 04107 Leipzig, Germany.
Publikováno v:
Pharmaceutics [Pharmaceutics] 2019 Nov 12; Vol. 11 (11). Date of Electronic Publication: 2019 Nov 12.