Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Norzehan Abdul-Manan"'
Autor:
Norzehan Abdul-Manan, Erik Henrich, Peter J. Connolly, Eduardo Perozo, Frank Löhr, Beate Hoffmann, Jonathan M. Moore, Aisha Laguerre, Frank Bernhard, Volker Dötsch
Publikováno v:
Structure. 24:1830-1841
Nanodiscs and isotropic bicelles are promising membrane mimetics in the field of solution nuclear magnetic resonance (NMR) spectroscopy of integral membrane proteins (IMPs). Despite varied challenges to solution NMR studies of IMPs, we attribute the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ba458aae6bf88d7911af3281d4c7742
https://doi.org/10.1016/j.str.2016.07.017
https://doi.org/10.1016/j.str.2016.07.017
Autor:
Norzehan Abdul-Manan, Joyce T. Coll, Jonathan M. Moore, Ernst ter Haar, Christopher M. Koth, Lora Swenson, Judith A. Lippke, Miguel Garcia-Guzman, Christopher A. Lepre
Publikováno v:
Structure. 18(9):1083-1093
SummaryDysregulation of the calcitonin gene-related peptide (CGRP), a potent vasodilator, is directly implicated in the pathogenesis of migraine. CGRP binds to and signals through the CGRP receptor (CGRP-R), a heterodimer containing the calcitonin re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7672cd8c9b99aedc175112fae92c9d84
Autor:
Jonathan M. Moore, Judith A. Lippke, Debra L. Brennan, Carlos H. Faerman, Norzehan Abdul-Manan, Xun Liu, Melissa Swope Willis, Scott A. Raybuck, Christian H. Gross, Prakash Prabhakar, Patrick R. Connelly, John R. Fulghum
Publikováno v:
Journal of Biological Chemistry. 281:4058-4068
The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel in the ATP-binding cassette (ABC) transporter family. CFTR consists of two transmembrane domains, two nucleotide-binding domains (NBD1 and NBD2), and a regulatory doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528b2bf96462e6ca723c84ab149972f4
https://doi.org/10.1074/jbc.m511113200
https://doi.org/10.1074/jbc.m511113200
Publikováno v:
Progress in Nuclear Magnetic Resonance Spectroscopy. 44:225-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838bda48f8f8e85b32f7fd76962c798e
https://doi.org/10.1016/j.pnmrs.2004.03.001
https://doi.org/10.1016/j.pnmrs.2004.03.001
Autor:
Franz Tumulka, Frank Löhr, Rupert Abele, Norzehan Abdul-Manan, Jonathan M. Moore, Aisha Laguerre, Sina Reckel, Volker Dötsch, Christoph Bock, Peter J. Connolly
Publikováno v:
Journal of magnetic resonance (San Diego, Calif. : 1997). 248
Combinatorial triple-selective labeling facilitates the NMR assignment process for proteins that are subject to signal overlap and insufficient signal-to-noise in standard triple-resonance experiments. Aiming at maximum amino-acid type and sequence-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e22840835b584c0a79e4298b17f727
https://pubmed.ncbi.nlm.nih.gov/25442777
https://pubmed.ncbi.nlm.nih.gov/25442777
Publikováno v:
Nature. 404:151-158
The Rho-family GTPase, Cdc42, can regulate the actin cytoskeleton through activation of Wiskott-Aldrich syndrome protein (WASP) family members. Activation relieves an autoinhibitory contact between the GTPase-binding domain and the carboxy-terminal r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5eedc5c90d5e88439e80b0649f21b9
https://doi.org/10.1038/35004513
https://doi.org/10.1038/35004513
Autor:
Behzad Aghazadeh, Katherine A. Siminovitch, Norzehan Abdul-Manan, Grace A. Liu, Ananya Majumdar, Ouathek Ouerfelli, Michael K. Rosen
Publikováno v:
Nature. 399:379-383
The Rho-family GTP-hydrolysing proteins (GTPases), Cdc42, Rac and Rho, act as molecular switches in signalling pathways that regulate cytoskeletal architecture, gene expression and progression of the cell cycle. Cdc42 and Rac transmit many signals th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f8c1cc6121ab03e06404df79de1073
https://doi.org/10.1038/20726
https://doi.org/10.1038/20726
Publikováno v:
Nucleic Acids Research. 24:4063-4070
To understand the range of possible and probable A1 functions in pre-mRNA biogenesis, it is important that we quantify the relative ability (or inability) of A1 to bind high affinity RNA target sequences and/or structures. Using a fluorescence compet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ebc0034627b162773ed5a204f4152f
https://doi.org/10.1093/nar/24.20.4063
https://doi.org/10.1093/nar/24.20.4063
Publikováno v:
Scopus-Elsevier
One of the most common motifs for binding RNA in eukaryotes is the RNA binding domain (RBD) or RNA Recognition Motif (RRM). One of the more intriguing aspects of these proteins is their modular nature. Proteins have been found containing from one to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94975164d4ed43c2afa2b2f3904ddce
https://doi.org/10.1093/nar/23.5.725
https://doi.org/10.1093/nar/23.5.725
Autor:
Frank Bernhard, Peter J. Connolly, Mikhail Karbyshev, Norzehan Abdul-Manan, Frank Löhr, Sina Reckel, Volker Dötsch, Jonathan M. Moore
Publikováno v:
Journal of biomolecular NMR. 52(3)
Obtaining NMR assignments for slowly tumbling molecules such as detergent-solubilized membrane proteins is often compromised by low sensitivity as well as spectral overlap. Both problems can be addressed by amino-acid specific isotope labeling in con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1586ecf36bb6f42686e54a6e7bcebf14
https://pubmed.ncbi.nlm.nih.gov/22252484
https://pubmed.ncbi.nlm.nih.gov/22252484