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pro vyhledávání: '"Norwegian Breast Cancer Group trial NBCG VI"'
Autor:
Stian Knappskog, Liv B Gansmo, Pål Romundstad, Merete Bjørnslett, Jone Trovik, Jan Sommerfelt-Pettersen, Erik Løkkevik, Norwegian Breast Cancer Group trial NBCG VI, Rob A E M Tollenaar, Caroline Seynaeve, Peter Devilee, Helga B Salvesen, Anne Dørum, Kristian Hveem, Lars Vatten, Per E Lønning
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e36263 (2012)
The MDM2 proto-oncogene plays a key role in central cellular processes like growth control and apoptosis, and the gene locus is frequently amplified in sarcomas. Two polymorphisms located in the MDM2 promoter P2 have been shown to affect cancer risk.
Externí odkaz:
https://doaj.org/article/73927cc6763348dd8815069ae625c8b3