Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish

Autor: Antón-Galindo E, Dalla Vecchia E, Orlandi JG, Castro G, Gualda EJ, Young AMJ, Guasch-Piqueras M, Arenas C, Herrera-Úbeda C, Garcia-Fernàndez J, Aguado F, Loza-Alvarez P, Cormand B, Norton WHJ, Fernandez N

Publikováno v: MOLECULAR PSYCHIATRY
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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Genetic variants in YWHAZ contribute to psychiatric disorders such as autism spectrum disorder and schizophrenia, and have been related to an impaired neurodevelopment in humans and mice. Here, we have used zebrafish to investigate the mechanisms by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::6421d28dccaaaec8e9b805b1222b9589
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=21460

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SRPK3 Is Essential for Cognitive and Ocular Development in Humans and Zebrafish, Explaining X-Linked Intellectual Disability.

Autor: Roychaudhury A; Department of Biology, Chungnam National University, Daejeon, South Korea., Lee YR; Department of Biology, Chungnam National University, Daejeon, South Korea., Choi TI; Department of Biology, Chungnam National University, Daejeon, South Korea., Thomas MG; The University of Leicester Ulverscroft Eye Unit, Department of Neuroscience, Psychology and Behavior, University of Leicester, Leicester, UK., Khan TN; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Yousaf H; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Skinner C; Greenwood Genetic Center, Greenwood, SC, USA., Maconachie G; The University of Leicester Ulverscroft Eye Unit, Department of Neuroscience, Psychology and Behavior, University of Leicester, Leicester, UK.; Division of Ophthalmology and Orthoptics, Health Science School, University of Sheffield, Sheffield, UK., Crosier M; Human Developmental Biology Resource, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Horak H; Department of Neurology, University of Arizona, Tucson, AZ, USA., Constantinescu CS; Academic Unit of Mental Health and Clinical Neuroscience, University of Nottingham, Nottingham, UK.; Cooper Neurological Institute and Cooper Medical School of Rowan University, Camden, NJ, USA., Kim TY; Department of Biology, Chungnam National University, Daejeon, South Korea., Lee KH; Department of Biology, Chungnam National University, Daejeon, South Korea., Kyung JJ; Department of Biology, Chungnam National University, Daejeon, South Korea., Wang T; McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA., Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South Korea., Chodirker BN; Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Hammer MF; BIO5 Institute, University of Arizona, Tucson, AZ, USA., Gottlob I; The University of Leicester Ulverscroft Eye Unit, Department of Neuroscience, Psychology and Behavior, University of Leicester, Leicester, UK.; Cooper Neurological Institute and Cooper Medical School of Rowan University, Camden, NJ, USA., Norton WHJ; Department of Genetics and Genome Biology, University of Leicester, Leicester, UK., Gerlai R; Department of Psychology, University of Toronto Mississauga, Mississauga, ON, Canada., Kim HG; Neurological Disorders Research Center, Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Doha, Qatar., Graziano C; Medical Genetics Unit, AUSL Romagna, Cesena, Italy., Pippucci T; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Iovino E; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Montanari F; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Severi G; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy., Toro C; NIH Undiagnosed Diseases Program, NIH Office of Rare Diseases Research and NHGRI, Bethesda, MD, USA., Boerkoel CF; NIH Undiagnosed Diseases Program, NIH Office of Rare Diseases Research and NHGRI, Bethesda, MD, USA., Cha HS; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Choi CY; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Kim S; Department of Microbiology & Molecular Biology, Chungnam National University, Daejeon, South Korea., Yoon JH; Department of Oncology Science, University of Oklahoma, Oklahoma City, OK, USA., Gilmore K; Division of Maternal Fetal Medicine, Department of Ob/Gyn, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Vora NL; Division of Maternal Fetal Medicine, Department of Ob/Gyn, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Davis EE; Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.; Department of Pediatrics, Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Chudley AE; Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada., Schwartz CE; Greenwood Genetic Center, Greenwood, SC, USA.; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA., Kim CH; Department of Biology, Chungnam National University, Daejeon, South Korea.

Publikováno v: Annals of neurology [Ann Neurol] 2024 Nov; Vol. 96 (5), pp. 914-931. Date of Electronic Publication: 2024 Jul 29.

Exposure Effects of Environmentally Relevant Concentrations of the Tricyclic Antidepressant Amitriptyline in Early Life Stage Zebrafish.

Autor: Gould SL; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Winter MJ; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Trznadel M; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Lange A; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Hamilton CM; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Boreham RJ; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Hetheridge MJ; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K., Young A; Department of Genetics and Genome Biology, College of Life Sciences, University of Leicester, University Rd., Leicester LE1 7RH, U.K., Norton WHJ; Department of Genetics and Genome Biology, College of Life Sciences, University of Leicester, University Rd., Leicester LE1 7RH, U.K., Tyler CR; Biosciences, Faculty of Health and Life Sciences, University of Exeter, Stocker Road, Exeter, Devon EX4 4QD, U.K.

Publikováno v: Environmental science & technology [Environ Sci Technol] 2024 Jul 17. Date of Electronic Publication: 2024 Jul 17.