Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Norsalsolinol"'
Autor:
Philipp Capetian, Andreas Moser, Regina Taurines, Manfred Gerlach, Caroline Korte, Franz Riederer, Veit Roessner, Susanne Walitza
Publikováno v:
Journal of Neural Transmission
Tetrahydroisoquinolines (TIQs) such as salsolinol (SAL), norsalsolinol (NSAL) and their methylated derivatives N-methyl-norsalsolinol (NMNSAL) and N-methyl-salsolinol (NMSAL), modulate dopaminergic neurotransmission and metabolism in the central nerv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94cf4e1002565e0a44d004e89daa9a43
http://europepmc.org/articles/PMC7815570
http://europepmc.org/articles/PMC7815570
Publikováno v:
Biological and Pharmaceutical Bulletin. 41:1581-1585
The objective of this study was to confirm the effect of maternal genistein exposure on body weight of male offspring and the metabolic alterations associated with maternal genistein-induced obesity. Pregnant female Sprague-Dawley (SD) rats were supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8365dd52771931c0cdf8552f39110eb6
https://doi.org/10.1248/bpb.b18-00317
https://doi.org/10.1248/bpb.b18-00317
Autor:
Ueoka, Reiko, Horiuchi, Naoki, Rotinsulu, Henki, Mangindaan, Remy E. P., Ukai, Kazuya, Kobayashi, Hisayoshi, Namikoshi, Michio, Hirota, Hiroshi, Yokosawa, Hideyoshi, Yumiko, Nagasawa, Reiko, Ueoka, Rumi, Yamanokuchi, Naoki, Horiuchi, Tsuyoshi, Ikeda, Henki, Rotinsulu, Remy E. P., Mangindaan, Kazuya, Ukai, Hisayoshi, Kobayashi, Michio, Namikoshi, Hiroshi, Hirota, Hideyoshi, Yokosawa, Sachiko, Tsukamoto
Publikováno v:
Chemical and Pharmaceutical Bulletin. 59:287-290
Salsolinol (1), a tetrahydroisoquinoline alkaloid, was isolated from the marine sponge Xestospongia cf. vansoesti collected in Indonesia as a proteasome inhibitor, along with three salsolinol derivatives, norsalsolinol (2), cis-4-hydroxysalsolinol (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b930bb62c9842439a21ebe676b2e9db
https://doi.org/10.1248/cpb.59.287
https://doi.org/10.1248/cpb.59.287
Publikováno v:
ELECTROPHORESIS. 31:1886-1893
Micellar electrokinetic chromatography coupled to amperometric electrochemical detection was used to resolve and then quantify biogenic amines and metabolites within the fruit fly Drosophila melanogaster. A new separation scheme was devised to allow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8afa39e834a6f4d9e4e6b783d901717c
https://doi.org/10.1002/elps.200900761
https://doi.org/10.1002/elps.200900761
Akademický článek
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Autor:
Kiyoshi Fukuhara, Yuki Yada, Yusuke Hiraku, Mariko Murata, Hatasu Kobayashi, Saeko Tada-Oikawa, Shinji Oikawa
Publikováno v:
Journal of Neurochemistry. 108:397-407
Tetrahydroisoquinoline (TIQ) derivatives are putative neurotoxins that may contribute to the degeneration of dopaminergic neurons in Parkinson's disease. One TIQ, norsalsolinol (NorSAL), is present in dopamine-rich areas of human brain, including the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5ba0ec79877da57b5827edc5fa8f3b
https://doi.org/10.1111/j.1471-4159.2008.05774.x
https://doi.org/10.1111/j.1471-4159.2008.05774.x
Autor:
Dorothy Schroeder, Mark S. LeDoux, Michael DeCuypere, Duane D. Miller, Ruyi Hao, Vassilios N. Kalabokis
Publikováno v:
Journal of Neuroscience Research. 86:2543-2552
The isoquinoline derivative N-methyl-6,7-dihydroxytetrahydroisoquinoline (N-methyl-norsalsolinol) is present in normal human brain and has been identified in the cerebrospinal fluid of patients with Parkinson's disease (PD). Endogenously, N-methyl-no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9221326101b1ee8eea91cbf2857ef951
https://doi.org/10.1002/jnr.21691
https://doi.org/10.1002/jnr.21691
Autor:
Joachim Scholz, Volker Schünemann, Alexander Luborzewski, Karen Toska, Andreas Moser, Astrid Maass, Jan Haavik
Publikováno v:
FEBS Journal. 275:2109-2121
N-methyl-norsalsolinol and related tetrahydroisoquinolines accumulate in the nigrostriatal system of the human brain and are increased in the cerebrospinal fluid of patients with Parkinson’s disease. We show here that 6,7-dihydroxylated tetrahydroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79a20e0379b3d19b88b8b71a9b17b30c
https://doi.org/10.1111/j.1742-4658.2008.06365.x
https://doi.org/10.1111/j.1742-4658.2008.06365.x
Autor:
Hans Uwe Wolf, Rainer Ortmann, Johannes Schwarz, Kazuo Matsubara, Alexander Storch, Yu I Hwang, Stefan Frenzel, Andreas Hein, Stefanie Ott, Shigeru Ohta
Publikováno v:
Biochemical Pharmacology. 63:909-920
Endogenous isoquinoline (IQ) derivatives structurally related to the selective dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its active metabolite 1-methyl-4-phenylpyridine (MPP(+)) may contribute to dopaminergic neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd4f1e2ae2f1cc529a09b11393311c4
https://doi.org/10.1016/s0006-2952(01)00922-4
https://doi.org/10.1016/s0006-2952(01)00922-4
Autor:
Ansgar, Thümen, Anne, Behnecke, Fatimunnisa, Qadri, Englbert, Bäuml, C Anne, Behnecke, Andreas, Moser
Publikováno v:
Neuroreport. 13:25-28
In earlier studies the dihydroxylated tetrahydroisoquinoline derivatives salsolinol and 2(N)-methyl-norsalsolinol (NMNorsal), a 2(N)-analogue of salsolinol, were identified as putative endogenous neurotoxins in patients with Parkinson's disease. Sinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc7f979329b98347ae961a1144b32960
https://doi.org/10.1097/00001756-200201210-00010
https://doi.org/10.1097/00001756-200201210-00010