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Obesity diminishes response to PD-1-based immunotherapies in renal cancer.

Autor: Boi SK; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Orlandella RM; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Gibson JT; Graduate Biomedical Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Turbitt WJ; Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Wald G; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Thomas L; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Buchta Rosean C; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Norris KE; Honors Undergraduate Research Program, School of Health Professions, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Bing M; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Bertrand L; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Gross BP; Interdisciplinary Program in Immunology, The University of Iowa, Iowa City, Iowa, USA., Makkouk A; Interdisciplinary Program in Immunology, The University of Iowa, Iowa City, Iowa, USA., Starenki D; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA., Farag KI; Science and Technology Honors Program, College of Arts and Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Sorge RE; Department of Psychology, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Brown JA; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Gordetsky J; Departments of Pathology and Urology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Yasin H; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Department of Internal Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Garje R; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Genitourinary Oncology Program, Division of Hematology, Oncology and Blood and Marrow Transplantation, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Nandagopal L; Division of Hematology and Oncology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA.; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA., Weiner GJ; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Department of Internal Medicine, Division of General Medicine, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA., Lubaroff DM; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Arend RC; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.; Department of Obstetrics and Gynecology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA., Li P; Department of Biostatistics, The University of Alabama at Birmingham School of Nursing, Birmingham, Alabama, USA., Zakharia Y; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Genitourinary Oncology Program, Division of Hematology, Oncology and Blood and Marrow Transplantation, The University of Iowa, Iowa City, Iowa, USA., Yang E; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.; Department of Radiation Oncology, The University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA., Salem AK; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA.; Division of Pharmaceutics and Translational Therapeutics, University of Iowa College of Pharmacy, Iowa City, Iowa, USA., Nepple K; Department of Urology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, Iowa, USA.; University of Iowa Holden Comprehensive Cancer Center, Iowa City, Iowa, USA., Marquez-Lago TT; Department of Genetics, The University of Alabama at Birmingham, Birmingham, Alabama, USA.; Department of Cell, Developmental and Integrative Biology, The University of Alabama at Birmingham, Birmingham, Alabama, USA., Norian LA; Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, Alabama, USA lnorian@uab.edu.; The University of Alabama at Birmingham O'Neal Comprehensive Cancer Center, Birmingham, Alabama, USA.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2020 Dec; Vol. 8 (2).

Total synthesis of a tyrosine suppressor transfer RNA gene. XVI. Enzymatic joinings to form the total 207-base pair-long DNA.

Autor: Sekiya T, Takeya T, Brown EL, Belagaje R, Contreras R, Fritz HJ, Gait MJ, Lees RG, Ryan MJ, Khorana HG, Norris KE

Publikováno v: The Journal of biological chemistry [J Biol Chem] 1979 Jul 10; Vol. 254 (13), pp. 5787-801.