Developing a placebo-controlled trial in surgery: Issues of design, acceptability and feasibility

Autor: McDonald AM, Sutherland AG, Skea ZC, Cuthbertson BH, Entwistle VA, Campbell MK, Norrie JD, Carlson RV, Bridgman S

Publikováno v: Trials, Vol 12, Iss 1, p 50 (2011)

Abstract Background Surgical placebos are controversial. This in-depth study explored the design, acceptability, and feasibility issues relevant to designing a surgical placebo-controlled trial for the evaluation of the clinical and cost effectivenes

Externí odkaz: https://doaj.org/article/1bbd598e41c54cc5822e690e603aab9c

Remdesivir for COVID-19: challenges of underpowered studies.

Autor: Norrie JD; Edinburgh Clinical Trials Unit, Usher Institute, Edinburgh EH16 4UX, UK. Electronic address: j.norrie@ed.ac.uk.

Publikováno v: Lancet (London, England) [Lancet] 2020 May 16; Vol. 395 (10236), pp. 1525-1527. Date of Electronic Publication: 2020 Apr 29.

Improving the Quality of Dentistry (IQuaD): a cluster factorial randomised controlled trial comparing the effectiveness and cost-benefit of oral hygiene advice and/or periodontal instrumentation with routine care for the prevention and management of periodontal disease in dentate adults attending dental primary care.

Autor: Ramsay CR; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Clarkson JE; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Duncan A; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Lamont TJ; Dundee Dental School, University of Dundee, Dundee, UK., Heasman PA; The Dental School, Newcastle University, Newcastle upon Tyne, UK., Boyers D; Health Economics Research Unit, University of Aberdeen, Aberdeen, UK., Goulão B; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Bonetti D; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Bruce R; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., Gouick J; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Heasman L; The Dental School, Newcastle University, Newcastle upon Tyne, UK., Lovelock-Hempleman LA; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Macpherson LE; Dental Health Services Research Unit, University of Dundee, Dundee, UK., McCracken GI; The Dental School, Newcastle University, Newcastle upon Tyne, UK., McDonald AM; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., McLaren-Neil F; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Mitchell FE; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Norrie JD; Health Services Research Unit, University of Aberdeen, Aberdeen, UK., van der Pol M; Health Economics Research Unit, University of Aberdeen, Aberdeen, UK., Sim K; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Steele JG; The Dental School, Newcastle University, Newcastle upon Tyne, UK., Sharp A; The Dental School, Newcastle University, Newcastle upon Tyne, UK., Watt G; Dental Health Services Research Unit, University of Dundee, Dundee, UK., Worthington HV; The School of Dentistry, University of Manchester, Manchester, UK., Young L; NHS Education for Scotland, Edinburgh, UK.

Publikováno v: Health technology assessment (Winchester, England) [Health Technol Assess] 2018 Jul; Vol. 22 (38), pp. 1-144.

Response to Letter from Wong on determining the target difference in sample size calculations for randomised controlled trials.

Autor: Cook, Jonathan A.¹ (AUTHOR), Parker, Richard A.² (AUTHOR) Richard.Parker@ed.ac.uk

Publikováno v: Trials. 3/2/2024, Vol. 25 Issue 1, p1-4. 4p.

Drug resistance predictive utility of age of onset and cortical imaging abnormalities in epilepsy: a systematic review and meta-analysis.

Autor: Alare, Kehinde^1,2 (AUTHOR) alarekehindepaul@gmail.com, Ogungbemi, Bridget¹ (AUTHOR), Fagbenro, Ayomide¹ (AUTHOR), Adetunji, Busayo^1,2 (AUTHOR), Owonikoko, Oladoja¹ (AUTHOR), Omoniyo, Taiwo^1,2 (AUTHOR), Jagunmolu, Habiblah^1,2 (AUTHOR), Kayode, Ayomide^1,2 (AUTHOR), Afolabi, Samson^1,2 (AUTHOR)

Publikováno v: Egyptian Journal of Neurology, Psychiatry & Neurosurgery. 1/10/2024, Vol. 60 Issue 1, p1-11. 11p.