Opioid-positive urine drug screen during treatment with oral naltrexone and the clinical implications

Autor: Elena R. Beauregard, PharmD, BCPS, Elizabeth G. Maguire, PMHNP-BC, CARN-AP

Publikováno v: Mental Health Clinician, Vol 14, Iss 2, Pp 102-106 (2024)

Introduction Naltrexone is an opioid antagonist that is FDA approved to treat alcohol dependence and opioid dependence. It is available as an oral tablet and an extended-release injectable suspension. Naltrexone is metabolized to the primary metaboli

Externí odkaz: https://doaj.org/article/ced53ba4a2dc4ade8b5bc2580b1770ab

Oxycodone Concentrations and Metabolic Ratios in Femoral Blood from Fatal Intoxications and Other Causes of Death using LC–MS-MS

Autor: Henrik Gréen, Robert Kronstrand, Gerd Jakobsson

Publikováno v: Journal of Analytical Toxicology. 45:124-133

Oxycodone (OC) is an opioid with strong analgesic effects widely used to treat acute and chronic pain. Interpretation of OC concentrations in postmortem cases is complicated due to tolerance and overlapping concentrations for fatal and non-fatal leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54a49f7db6401781e28cadf1daac933
https://doi.org/10.1093/jat/bkaa051

Population Pharmacokinetics of Oxycodone and Metabolites in Patients with Cancer-Related Pain

Autor: Ron H.J. Mathijssen, Carin C.D. van der Rijt, Sebastiaan D.T. Sassen, Birgit C. P. Koch, Bram C. Agema, Astrid W. Oosten, Stijn L.W. Koolen, Wim J R Rietdijk

Publikováno v: Cancers, Vol 13, Iss 2768, p 2768 (2021)
Cancers
Volume 13
Issue 11
Cancers, 13(11):2768. Multidisciplinary Digital Publishing Institute (MDPI)

Oxycodone is frequently used for treating cancer-related pain, while not much is known about the factors that influence treatment outcomes in these patients. We aim to unravel these factors by developing a population-pharmacokinetic model to assess t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01538e78b3c04ce9eba8ddfe28041d52
https://www.mdpi.com/2072-6694/13/11/2768

The Quantification of Oxycodone and Its Phase I and II Metabolites in Urine

Autor: Madeleine J. Swortwood, Robert Kronstrand, Henrik Gréen, Maria D. Chermá, Michael T. Truver, Gerd Jakobsson

The purpose of this research was to develop and validate an analytical method for the detection and quantification of noroxymorphone-3s-D-glucuronide, oxymorphone-3s-D-glucuronide, noroxymorphone, oxymorphone, 6α-oxycodol, 6β-oxycodol, noroxycodone

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e081b1934014c278bce04bd278197e90
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-184416

Quality Assessment of Expired Naloxone Products from First-Responders’ Supplies

Autor: Justin Frey, Michael W. Dailey, Michael Brodeur, Schuyler Pruyn, Benjamin Baker, Carla Graichen, Haian Zheng, Heather Long

Publikováno v: Prehospital Emergency Care. 23:647-653

Objective: Naloxone is an opioid receptor antagonist that reverses life-threatening effects of opioid overdose. Since the 1970s, naloxone products have been developed as injectable solutions, and more recently as nasal sprays. Naloxone products have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd89fe144df98c26891b873baecbe64
https://doi.org/10.1080/10903127.2018.1563257