Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Normann Steiner"'
Autor:
Verena Petzer, Normann Steiner, Olga Angelova-Unterberger, Gabriele Hetzenauer, Kathrin Philipp-Abbrederis, Ella Willenbacher, Clemens Feistritzer, Wolfgang Willenbacher, Jakob Rudzki, Reinhard Stauder, Florian Kocher, Andreas Seeber, Andreas Pircher, Piotr Tymoszuk, Christian Irsara, Alexander Egger, Vilmos Fux, Markus Anliker, Eberhard Gunsilius, David Nachbaur, Stefan Schmidt, Dominik Wolf
Publikováno v:
HemaSphere, Vol 6, Iss 3, p e686 (2022)
Externí odkaz:
https://doaj.org/article/74bd0f2cddf64100b6d46bc8aadf97c0
Autor:
Normann Steiner, Georg Göbel, Leonie Mauser, Lena Mühlnikel, Marie Fischinger, Tina Künz, Wolfgang Willenbacher, Gabriele Hetzenauer, Jakob Rudzki, Walter Nussbaumer, Wolfgang Mayer, Eberhard Gunsilius, Brigitte Kircher, Dominik Wolf, David Nachbaur
Publikováno v:
Cancers, Vol 15, Iss 3, p 608 (2023)
In our single-center study, 357 myeloma and lymphoma patients between 2009 and 2019 were mobilized with granulocyte colony-stimulating factor (G-CSF 7.5 µg/kg bid for four days) plus a fixed dose of 24 mg Plerixafor when indicated (Plerixafor Group,
Externí odkaz:
https://doaj.org/article/5385f1713a9b4837a4132ee695b6fbcd
Autor:
Tina Künz, Alexander W. Hauswirth, Gabriele Hetzenauer, Jakob Rudzki, David Nachbaur, Normann Steiner
Publikováno v:
Cancers, Vol 14, Iss 17, p 4290 (2022)
Acute lymphoblastic leukemia (ALL) is a rare hematological malignancy characterized by proliferation and accumulation of premature lymphoid blasts. Depending on risk factors, the survival of acute lymphoblastic leukemia has significantly improved ove
Externí odkaz:
https://doaj.org/article/bb903873057043ee915d93f85514e46c
Autor:
Bojana Borjan, Johann Kern, Normann Steiner, Eberhard Gunsilius, Dominik Wolf, Gerold Untergasser
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Background: Mechanisms mediating resistance against the proteasome inhibition by bortezomib (BTZ) in multiple myeloma (MM) cells are still unclear. We analyzed the activation of the unfolded protein response (UPR), induction of prosurvival, and apopt
Externí odkaz:
https://doaj.org/article/42c479e5f68944c3aa57c4fcfeab2822
Autor:
Irene Strassl, Martin Schreder, Normann Steiner, Jakob Rudzki, Hermine Agis, Tina Künz, Nino Müser, Wolfgang Willenbacher, Andreas Petzer, Peter Neumeister, Maria Theresa Krauth
Publikováno v:
Cancers, Vol 13, Iss 18, p 4701 (2021)
Since the introduction of first-generation proteasome inhibitors and immunomodulatory agents, the multiple myeloma (MM) treatment landscape has undergone a remarkable development. Most recently, immunotherapeutic strategies targeting the B cell matur
Externí odkaz:
https://doaj.org/article/932fb0ebbc4846d290f19f12b9f422ae
Autor:
Normann Steiner, Karin Jöhrer, Selina Plewan, Andrea Brunner-Véber, Georg Göbel, David Nachbaur, Dominik Wolf, Eberhard Gunsilius, Gerold Untergasser
Publikováno v:
Cancers, Vol 12, Iss 9, p 2341 (2020)
Therapy resistance remains a major challenge in the management of multiple myeloma (MM). We evaluated the expression of FLT3 tyrosine kinase receptor (FLT3, CD135) in myeloma cells as a possible clonal driver. FLT3 expression was analyzed in bone mar
Externí odkaz:
https://doaj.org/article/28398252df4d4f279e557a0efbf233fd
Autor:
Normann Steiner, Udo Müller, Roman Hajek, Sabina Sevcikova, Bojana Borjan, Karin Jöhrer, Georg Göbel, Andreas Pircher, Eberhard Gunsilius
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202045 (2018)
INTRODUCTION:Multiple myeloma (MM), a malignant plasma cell disorder, is still an incurable disease. Thus, the identification of novel therapeutic targets is of utmost importance. Here, we evaluated the peripheral blood-based metabolic profile of pat
Externí odkaz:
https://doaj.org/article/fc19231787ba455784dd49ffac371356
Autor:
Normann Steiner, Roman Hajek, Sabina Sevcikova, Bojana Borjan, Karin Jöhrer, Georg Göbel, Gerold Untergasser, Eberhard Gunsilius
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181487 (2017)
Multiple myeloma (MM) is still incurable due to resistance against various therapies. Thus, the identification of biomarkers predicting progression is urgently needed. Here, we evaluated four biomarkers in bone marrow and peripheral blood of MM patie
Externí odkaz:
https://doaj.org/article/3b7a76afd8524869a87431bd32af28a3
Autor:
Wolfgang Willenbacher, Andreas Seeber, Normann Steiner, Ella Willenbacher, Zoran Gatalica, Jeff Swensen, Jeffery Kimbrough, Semir Vranic
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 2087 (2018)
Multiple myeloma (MM), the second most common hematologic malignancy, is characterized by the clonal expansion of plasma cells. Despite dramatic improvements in patients′ survival over the past decade due to advances in therapy exploiting novel mol
Externí odkaz:
https://doaj.org/article/93d864122ffc468880ba6293534c135b
Autor:
NORMANN STEINER, PAULA SCHOBER, WOLFGANG WILLENBACHER, BRIGITTE KIRCHER, EBERHARD GUNSILIUS, DOMINIK WOLF, DAVID NACHBAUR
Publikováno v:
Anticancer research. 42(12)
Despite multiple treatment options, multiple myeloma (MM) remains an incurable disease with poor outcome.We retrospectively analyzed the outcome of MM patients undergoing an allogeneic (allo-SCT; n=34) or autologous stem cell transplantation (auto-SC