Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Normando Iznaga-Escobar"'
Autor:
Normando Iznaga Escobar, Anai García Fariñas, Leslie Pérez Ruiz, Manuel Collazo Herrera, Osvaldo Ulises Garay
Publikováno v:
PharmacoEconomics Spanish Research Articles. 15:13-23
Evaluar la eficiencia de la atencion a la salud recibida por los pacientes diagnosticados de cancer de celulas escamosas de cabeza y cuello en estadios avanzados, incluidos en el ensayo clinico fase iv realizado en Cuba. Evaluacion economica completa
Publikováno v:
PharmacoEconomics Spanish Research Articles. 13:133-140
Objetivo Evaluar la eficiencia de nimotuzumab en el tratamiento de los pacientes diagnosticados de cancer de cabeza y cuello incluidos en el ensayo clinico (EC).
Publikováno v:
Repositorio UN
Universidad Nacional de Colombia
instacron:Universidad Nacional de Colombia
Universidad Nacional de Colombia
instacron:Universidad Nacional de Colombia
Objetivo: Valorar la importancia de la introducción de los estudios de evaluación económica en el desarrollo de los ensayos clínicos con productos biotecnológicos. Métodos: Se realizó una revisión bibliográfica para argumentar el valor que t
Autor:
Henia Balter, Pablo Cabral, Susan L. Deutscher, Arlhee Diaz-Miqueli, Thomas P. Quinn, Marcelo Fernández, Xiuli Zhang, Normando Iznaga-Escobar, Victoria Calzada
Publikováno v:
Current Radiopharmaceuticals. 5:318-324
In this work Nimotuzumab (monoclonal antibody, recognizes the EGF-R) was radiolabeled with (177)Lu as a potential cancer therapy radiopharmaceutical. In-vitro cell binding studies and in-vivo biodistribution and imaging studies were performed to dete
Autor:
Rene Figueredo, Edilis Santana, Ángel Casacó Parada, Barbara Gonzalez Navarro, Pio Alvarez, A. León, Ana M. Bada, Normando Iznaga-Escobar, Rolando Pérez
Publikováno v:
Experimental and Toxicologic Pathology. 56:313-319
h-R3 is a humanized anti-epidermal growth factor receptor (EGFR) monoclonal antibody (MAb). This receptor is over-expressed in the majority of tumors of epithelial origin, including glioblastomas. 188Rhenium (188Re) constitutes an ideal radionuclide
Autor:
Agustin Lage, Enrique Renginfo, Carlos Roca, I. Leonard, Rene Figueredo, Teresa Cruz, Daniel Esteban Pineda Alvarez, Ramón del Castillo, Tania Crombet, Normando Iznaga-Escobar, Rolando Pérez, James Koropatnick, Rosa Mon, Eduardo Fernández, Marta Osorio, Olga Torres, Mayra Ramos
Publikováno v:
Journal of Clinical Oncology. 22:1646-1654
Purpose To evaluate safety and preliminary efficacy of the humanized anti-epidermal growth factor receptor monoclonal antibody h-R3 in combination with radiotherapy (RT) in unresectable head and neck cancer patients. Secondary end points were the mea
Autor:
Normando Iznaga-Escobar
Publikováno v:
Applied Radiation and Isotopes. 54:399-406
188Re is one of the radioisotopes expected to emerge as useful for therapy. Development of new radiopharmaceuticals based on 188Re depends on the radiolabeling methods used, which would give stable complexes having predefined radiochemical properties
Autor:
Alejo Morales-Morales, Normando Iznaga-Escobar, Gilda Núñez-Gandolff, Jorge Duconge, Eduardo Fernández, Idania Caballero-Torres
Publikováno v:
Nuclear Medicine and Biology. 26:275-279
The anti-human epidermal growth factor receptor (EGF-R) humanized monoclonal antibody (MAb) h-R3 is an (IgG1), which binds to an extracellular domain of EGF-R. It was used to evaluate the biodistribution on nude mice xenografted with H-125 human lung
Publikováno v:
Nuclear Medicine and Biology. 23:641-644
A simple, rapid, and reproducible micromethod for quantification of sulfhydryl (SH) groups generated after reduction of monoclonal antibody (MAb) disulfide bonds with 2-mercaptoethanol (2-ME) is described. The number of SH groups per molecule of anti
Autor:
Leonel A Torres Aroche, Juan P. Oliva, Obaya T Rodríguezi, Maria Cordero, Mayra Ramos-Suzarte, Joaquín González, Rodriguez Rolando Perez, Gilmara Pimentel, Normando Iznaga-Escobar, Ramos Tania Crombet, Nelson Rodriguez Mesa, Alejandro P Pintado
Publikováno v:
Cancer biologytherapy. 6(1)
Monoclonal antibody (mAb) ior c5 is an IgG1, which recognizes a glycoprotein tumor specific antigen IOR C2 over expressed in the surface of colon and ovarian cancer cells. The aim of the present work was to evaluate the diagnostic efficacy of the 99m