Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Normand, Cyr"'
Autor:
Kaylee Petraccione, Mohamed G H Ali, Normand Cyr, Haytham M Wahba, Timothy Stocker, Maryna Akhrymuk, Ivan Akhrymuk, Lauren Panny, Nicole Bracci, Raphaël Cafaro, Danuta Sastre, Andrew Silberfarb, Paul O'Maille, James Omichinski, Kylene Kehn-Hall
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1012093 (2024)
Rift Valley fever virus (RVFV) is a viral zoonosis that causes severe disease in ruminants and humans. The nonstructural small (NSs) protein is the primary virulence factor of RVFV that suppresses the host's antiviral innate immune response. Bioinfor
Externí odkaz:
https://doaj.org/article/080232048ca04318a75327164da80aa8
Autor:
Amogh Gopinathan Nair, Nick Rabas, Sara Lejon, Caleb Homiski, Michael J. Osborne, Normand Cyr, Aleksandr Sverzhinsky, Thomas Melendy, John M. Pascal, Ernest D. Laue, Katherine L. B. Borden, James G. Omichinski, Alain Verreault
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11099 (2022)
The eukaryotic DNA replication fork is a hub of enzymes that continuously act to synthesize DNA, propagate DNA methylation and other epigenetic marks, perform quality control, repair nascent DNA, and package this DNA into chromatin. Many of the enzym
Externí odkaz:
https://doaj.org/article/2e59bc152815426e9ca923121e0e3f23
Autor:
Anwar Hasil Kottarampatel, Terry K. Smith, Louis-Philippe Leroux, Amanda Davidsen, Armando Jardim, Normand Cyr, Christian Salesse, Elodie Boisselier
Publikováno v:
Biochemical Journal. 475:511-529
This work was funded by operating grants from the Canadian Institutes of Health Research (CIHR) and a Natural Sciences Engineering Research Council of Canada (NSERC) Discovery grant [Fonds de recherche du Québec — Nature et technologies (FRQNT) Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb3eb748cae4b1ceb4e874ed86bd0d9
https://doi.org/10.1042/bcj20170746
https://doi.org/10.1042/bcj20170746
Autor:
Normand Cyr
Publikováno v:
Biochemical Journal. 475:3917-3919
In a recent issue of Biochemical Journal, Kathuria et al. [Biochem. J. (2018) 475, 3039–3055] report that membrane binding of the pore-forming toxin Vibrio cholerae cytolysin (VCC) is facilitated by the presence of cholesterol, and the presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7ea68cc813eea2cf5c1f9722829b701
https://doi.org/10.1042/bcj20180728
https://doi.org/10.1042/bcj20180728
Autor:
Lauriane Lecoq, Pascale Legault, Philippe R. Chabot, James G. Omichinski, Geneviève Arseneault, Normand Cyr, Luca Raiola
Publikováno v:
Nucleic Acids Research
p65 is a member of the NF-κB family of transcriptional regulatory proteins that functions as the activating component of the p65–p50 heterodimer. Through its acidic transactivation domain (TAD), p65 has the capacity to form interactions with sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d8204b2d52ec28918c215b3abdc8b1
https://doi.org/10.1093/nar/gkx146
https://doi.org/10.1093/nar/gkx146
Autor:
Manon Couture, Normand Cyr, Julie Barma, Mahder Seifu Manenda, John M. Pascal, Xiaojun Zhu, Rong Shi, Changsheng Zhang, Li-Ping Zhang, Marie-Ève Picard
Publikováno v:
J Biol Chem
Group A flavin-dependent monooxygenases catalyze the cleavage of the oxygen-oxygen bond of dioxygen, followed by the incorporation of one oxygen atom into the substrate molecule with the aid of NADPH and FAD. These flavoenzymes play an important role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c491133e95c81b1dfea0311ef0b29be
https://pubmed.ncbi.nlm.nih.gov/32111738
https://pubmed.ncbi.nlm.nih.gov/32111738
Autor:
Lauriane Lecoq, James G. Omichinski, Normand Cyr, Philippe R. Chabot, Irene Guendel, Kylene Kehn-Hall, Cynthia de la Fuente
Publikováno v:
Proceedings of the National Academy of Sciences. 112:6021-6026
Rift Valley fever virus (RVFV) is a single-stranded RNA virus capable of inducing fatal hemorrhagic fever in humans. A key component of RVFV virulence is its ability to form nuclear filaments through interactions between the viral nonstructural prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbcd35dea3bc7633c470aba6d77119d
https://doi.org/10.1073/pnas.1503688112
https://doi.org/10.1073/pnas.1503688112
Autor:
Normand, Cyr, Terry K, Smith, Élodie, Boisselier, Louis-Philippe, Leroux, Anwar Hasil, Kottarampatel, Amanda, Davidsen, Christian, Salesse, Armando, Jardim
Publikováno v:
The Biochemical journal. 475(2)
Protein import into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::203e9ab1456575e020082549c7597aff
https://pubmed.ncbi.nlm.nih.gov/29259081
https://pubmed.ncbi.nlm.nih.gov/29259081
Autor:
Anwer Hasil Kottarampatel, Hamed Hojjat, Armando Jardim, Ana Victoria C. Pilar, James McLean, Normand Cyr, Rona Strasser, Elizabeth Quinn
Publikováno v:
Biochemical Journal. 460:273-282
LPEX7 (Leishmania peroxin 7) is essential for targeting newly synthesized proteins with a PTS2 (peroxisome-targeting signal type 2) import signal into the glycosome. In the present paper, we describe the biophysical characterization of a functional L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77783e2134c708cc13b0e02052967a7
https://doi.org/10.1042/bj20131628
https://doi.org/10.1042/bj20131628
Autor:
Dayal Dasanayake, Manon Richaud, Celia Caballero-Franco, Sabrina Pittroff, Juan Ausió, Michael S. Donnenberg, Armando Jardim, Ron M. Finn, Normand Cyr, Wensheng Luo
Publikováno v:
Molecular Microbiology. 81:734-750
Summary Enterohemorrhagic Escherichia coli is a causative agent of gastrointestinal and diarrheal diseases. These pathogenic E. coli express a syringe-like protein machine, known as the type III secretion system (T3SS), used for the injection of viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c396a8c92e1f1212835c23757011b770
https://doi.org/10.1111/j.1365-2958.2011.07727.x
https://doi.org/10.1111/j.1365-2958.2011.07727.x