Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Norman Wideburg"'
Autor:
H. L. Sham, Kent D. Stewart, Kennan C. Marsh, Chang H. Park, Thomas Herrin, Xiang-Peng Kong, C. Zhao, Dale J. Kempf, David A. Betebenner, J. J. Plattner, Akhter Molla, T. Robins, D. W. Norbeck, Shuqun Lin, Ayda Saldivar, N. Lyons, Darold L. Madigan, W. Jun. Rosenbrook, Edith McDonald, Jon F. Denissen, Norman Wideburg, Suthida Vasavanonda
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6f00d92d07b9ab95319d0efe6ff86a
https://doi.org/10.1002/chin.199619188
https://doi.org/10.1002/chin.199619188
Autor:
John Erickson, David J. Neidhart, John VanDrie, Dale J. Kempf, Xiu Chun Wang, Daniel W. Norbeck, Jacob J. Plattner, Judith W. Rittenhouse, Mary Turon, Norman Wideburg, William E. Kohlbrenner, Robert Simmer, Rosalind Helfrich, Deborah A. Paul, Mark Knigge
Publikováno v:
Science. 249:527-533
A two-fold (C2) symmetric inhibitor of the protease of human immunodeficiency virus type-1 (HIV-1) has been designed on the basis of the three-dimensional symmetry of the enzyme active site. The symmetric molecule inhibited both protease activity and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6828a26be7da42dbd14253153a7cdbe9
https://doi.org/10.1126/science.2200122
https://doi.org/10.1126/science.2200122
Autor:
John Hengeveld, Jack Tadanier, William Rosenbrook, David Whittern, Cheuk-Man Lee, Norman Wideburg
Publikováno v:
Carbohydrate Research. 201:209-222
Analogs of 3-deoxy- d - manno -octulosonic acid (Kdo) having the β-anomeric hydroxyl group replaced by a substituted-methyl group were prepared from Kdo. The substituted-methyl groups were derived from the carboxyl group of Kdo, whereas the carboxyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a559167e4b8effcf402c132c673192ef
https://doi.org/10.1016/0008-6215(90)84237-o
https://doi.org/10.1016/0008-6215(90)84237-o
Autor:
H. L. Sham, Sudthida Vasavanonda, Edith McDonald, J. J. Plattner, Shuqun Lin, D. W. Norbeck, Ayda Saldivar, T. Robins, K. C. Marsh, Chen Zhao, Dale J. Kempf, Norman Wideburg, David A. Betebenner
Publikováno v:
Biochemical and biophysical research communications. 211(1)
A series of novel pseudo-symmetrical and unsymmetrical inhibitors based on the backbone modification of a peptidomimetic were synthesized and found to be highly potent inhibitors of the HIV-1 protease (IC50 = 2.9 to < 0.5 nM). These compounds also po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ebdbdb1d2d8ed57a63760aa8d72c16c
https://pubmed.ncbi.nlm.nih.gov/7779082
https://pubmed.ncbi.nlm.nih.gov/7779082
Publikováno v:
Carbohydrate research. 201(2)
Selective C-8 modifications of 2,6-anhydro-3-deoxy-D-glycero-D-talo-octonic acid ("2,3-dideoxy-beta-D-manno-2-octulosonic acid", 1a) were effected via the protected 8-hydroxy derivatives 2d and 2e. Swern oxidation of 2d and 2e gave the aldehydes 3a a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2ce961ee60691100e7128e02b00ae6
https://pubmed.ncbi.nlm.nih.gov/2171764
https://pubmed.ncbi.nlm.nih.gov/2171764
Autor:
Lester A. Mitscher, George W. Clark. III, Gordon Bokelman, Hollis D. H. Showalter, Kunikatsu Shirahata, P. Bryan Hudson, Earl Fager, Norman Wideburg, R. Jack Theriault
Publikováno v:
HETEROCYCLES. 7:779
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ddc7ba1d6d9213bdf5a3b9981bb27d
https://doi.org/10.3987/s-1977-02-0779
https://doi.org/10.3987/s-1977-02-0779