Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Norman Violet"'
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100224- (2020)
Summary: Growth and offspring count are two commonly determined toxicological endpoints for chemical- or gene-induced developmental and reproductive effects in Caenorhabditis elegans. Here, we present a protocol for a 96 h, medium-throughput assay, a
Externí odkaz:
https://doaj.org/article/119207da1b4448b5b06f4f0ca20bd86c
Autor:
Johanna Ndikung, Dorothe Storm, Norman Violet, Achim Kramer, Gilbert Schönfelder, Norman Ertych, Michael Oelgeschläger
Publikováno v:
Environment International, Vol 134, Iss , Pp - (2020)
Background: The growing requirement of hazard and risk assessment of environmental chemicals and the efforts to minimize animal testing, increases the demand for innovative and predictive in vitro test systems in toxicology, reflecting the physiologi
Externí odkaz:
https://doaj.org/article/dcb8e196d2f1442fb7438b9ff3fb0101
Autor:
Matthias Steinfath, Silvia Vogl, Norman Violet, Franziska Schwarz, Hans Mielke, Thomas Selhorst, Matthias Greiner, Gilbert Schönfelder
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202762 (2018)
We developed a new probabilistic model to assess the impact of recommendations rectifying the reproducibility crisis (by publishing both positive and 'negative' results and increasing statistical power) on competing objectives, such as discovering ca
Externí odkaz:
https://doaj.org/article/e537d44c4e52467e9347e7b0c40490be
Autor:
Gilbert Schönfelder, Silvia Vogl, Paul Wittkowski, Verena Fetz, Michael Oelgeschläger, Norman Violet, Philip Marx-Stoelting, Franziska Schwarz
Publikováno v:
Environmental Science & Technology. 53:12725-12733
A key challenge of mixture toxicity testing is that a multitude of substances with even more combinations need to be tested in a broad dose range. Consequently testing in rodent bioassays, the current gold standard of toxicity testing, is hardly feas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2b6ae8f87d92ee543a2fd34c907cd2
https://doi.org/10.1021/acs.est.9b03266
https://doi.org/10.1021/acs.est.9b03266
Publikováno v:
Eng Life Sci
Although known to be very powerful, the widespread application of model‐based techniques is still significantly hampered in the area of bio‐processes. Reasons for this situation can be found along the whole chain to set up and implement such appr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a1b1bc20b86cc7ca05b130428d323c
https://doi.org/10.1002/elsc.201600020
https://doi.org/10.1002/elsc.201600020
Autor:
Gilbert Schönfelder, Michael Oelgeschläger, D. Storm, Norman Ertych, Johanna Ndikung, Norman Violet, Achim Kramer
Publikováno v:
Environment International, Vol 134, Iss, Pp-(2020)
Background: The growing requirement of hazard and risk assessment of environmental chemicals and the efforts to minimize animal testing, increases the demand for innovative and predictive in vitro test systems in toxicology, reflecting the physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e023b28811d662fab3f0dee465f7f7c
https://pubmed.ncbi.nlm.nih.gov/31734582
https://pubmed.ncbi.nlm.nih.gov/31734582
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100224-(2020)
STAR Protocols
STAR Protocols
Summary Growth and offspring count are two commonly determined toxicological endpoints for chemical- or gene-induced developmental and reproductive effects in Caenorhabditis elegans. Here, we present a protocol for a 96 h, medium-throughput assay, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bcf1676cda7fb24793f67d9166c4edd
https://doi.org/10.1016/j.xpro.2020.100224
https://doi.org/10.1016/j.xpro.2020.100224
Autor:
Franziska Schwarz, Norman Violet, Matthias Greiner, Silvia Vogl, Matthias Steinfath, Hans Mielke, Thomas Selhorst, Gilbert Schönfelder
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202762 (2018)
We developed a new probabilistic model to assess the impact of recommendations rectifying the reproducibility crisis (by publishing both positive and 'negative' results and increasing statistical power) on competing objectives, such as discovering ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5003dc11b1cc61e9800230948b0e14a0
http://europepmc.org/articles/PMC6135363?pdf=render
http://europepmc.org/articles/PMC6135363?pdf=render
Autor:
Rudibert King, Detlef Goelling, Peter Neubauer, Andreas Knepper, Gernot T. John, Norman Violet, Christine Lang, Sarina Arain, Antje Neubauer, Florian Glauche
Publikováno v:
SLAS Technology. 20:438-446
In this study, a slow-responding chemo-optical sensor for dissolved oxygen (DO) integrated into a 96-well plate was developed. The slow response time ensures that the measured oxygen value does not change much during plate transport to the microplate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a25494a315af318674fa1c267fb614
https://doi.org/10.1177/2211068215573924
https://doi.org/10.1177/2211068215573924
Autor:
Hans Mielke, Franziska Schwarz, Silvia Vogl, Matthias Steinfath, Norman Violet, Thomas Selhorst, Matthias Greiner, Gilbert Schönfelder
Assessing the impact of recommendations rectifying the reproducibility crisis (publishing both positive and “negative” results and increasing statistical power) on competing objectives, such as discovering causal relationships, avoiding publishin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c09dc7c1893dae821d6120c2fa3dbb
https://doi.org/10.1101/218867
https://doi.org/10.1101/218867
