Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Norman Talal"'
Publikováno v:
Stress, Immunity, and Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd435536295e06967fdcee7e7d914f18
https://doi.org/10.1201/9781003065180-17
https://doi.org/10.1201/9781003065180-17
Publikováno v:
Scandinavian Journal of Immunology. 23:415-423
Three strains of mice bearing the autosomal recessive lpr gene (MRL, C57BL/6, and C3H) that had spontaneously developed a lupus-like disease were studied sequentially for functional natural killer (NK) and natural cytotoxic (NC) cell activity. Natura
Autor:
Norman Talal, Xiao Bing Liu, Rejei Masago, Sonomi Aiba-Masago, Howard Dang, Che Ming A Lau, Victoria Frohlich, Fabio Jimenez, Norma Vela-Roch
Publikováno v:
Oncogene. 21:2762-2767
Bax is an oncogene that has proapoptotic properties but not all cells that express Bax undergo apoptosis. Bax may have a function unrelated to apoptosis. To elucidate the role of Bax in cell signaling, an epithelial cell line called SMG-C6 was transf
Autor:
Howard Dang, Sonomi Aiba-Masago, Chih Ko Yeh, G. Fernandes, Norma Vela-Roch, Fabio Jimenez, I. Al Hashimi, Norman Talal
Publikováno v:
Rheumatology. 41:338-342
Objective. Apoptosis is an organized energy-dependent process of cellular self-destruction carried out by proteolytic enzymes such as the caspases. These enzymes may play a role in epithelial cell apoptosis in Sjogren's syndrome (SS). A classical cas
Autor:
Sonomi Aiba-Masago, Norman Talal, Michael G. Humphreys-Beher, Howard Dang, C. Allen Lau, Ammon B. Peck, Reiji Masago, Ibtisam Al-Hashimi, Fabio Jimenez Zuluaga, Michael Moody, J. Brayer
Publikováno v:
Arthritis & Rheumatism. 44:693-702
Objective Salivary gland epithelial cells in patients with Sjogren's syndrome (SS) and in NOD and NOD.scid mice express Fas and Fas ligand, and these cells die from apoptosis. To elucidate the intracellular molecular mechanisms responsible for this s
Publikováno v:
Scandinavian Journal of Immunology. 50:479-484
The induction of T-cell apoptosis is regulated in part by monocytes (CD14+ cells). Human peripheral blood monocytes inhibited the spontaneous cell death of activated T cells in vitro. The inhibition of T-cell apoptosis did not require autologous mono
Autor:
Norman Talal, Juan-Manuel Anaya
Publikováno v:
Seminars in Arthritis and Rheumatism. 28:355-359
Primary Sjogren's syndrome (SS) is an autoimmune exocrine disease characterized by salivary and lacrimal gland destruction progressing to xerostomia and xerophthalmia (sicca symptoms). Nevertheless, any exocrine as well as nonexocrine organ may be in
Publikováno v:
Clinical and Experimental Immunology. 116:383-387
The aetiopathogenesis of autoimmune disorders has remained elusive despite much effort over many years devoted to possible genetic, viral and hormonal mechanisms [1,2]. Although genes, viruses, and sex hormones are no doubt involved, a key factor ana
Publikováno v:
Cytokine. 11:187-191
T lymphocytes from several autoimmune diseases including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) exhibit deficient mitogenic response in terms of proliferation and IL-2 production. The expression of the IL-2 gene is regulated