Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Norman R. Hughes"'
Autor:
Meri Najdovska, Catherine Kennedy, Chia Huey Ooi, Patrick Tan, Cody C. Allison, Norman R. Hughes, Brendan J. Jenkins, Richard L. Ferrero, Prithi S. Bhathal, Anouk Dev, Gareth W. Jones, William Sievert, Louise McLeod, Simon Arnett Jones
Publikováno v:
The Journal of Pathology. 225:255-264
Chronic activation of the gastric mucosal adaptive immune response is a characteristic trait of gastric cancer. It has recently emerged that a new class of T helper (Th) cells, defined by their ability to produce interleukin (IL)-17A (Th17), is assoc
Publikováno v:
Journal of Clinical Pathology. 59:1073-1078
Aim: To compare cell phenotypes displayed by cholangiocarcinomas and adjacent bile duct lesions in patients from an area endemic in liver-fluke infestation and those with sporadic cholangiocarcinoma. Methods: 65 fluke-associated and 47 sporadic chola
Autor:
Gregory Y. Lauwers, Norman R. Hughes, Heike Varnholt, Prithi S. Bhathal, Paola Dal Cin, Jean Nicolas Vauthey, Robert W. De Marsh
Publikováno v:
The American Journal of Surgical Pathology. 27:693-698
We report a case of biliary adenofibroma in a 47-year-old woman, who presented with right upper quadrant pain for several months. Abdominal imaging revealed a 16-cm solid and cystic mass in the left hepatic lobe. Histologically, the tumor showed two
Publikováno v:
The American Journal of Surgical Pathology. 20:858-864
The cell phenotype of so-called bile duct adenoma (BDA) was investigated immunohistochemically using monoclonal antibodies to two recently identified antigens (designated D10 and 1F6) extracted from human liver and cultured biliary epithelium. The ac
Adenocarcinoma of gallbladder: an immunohistochemical profile and comparison with cholangiocarcinoma
Autor:
Prithi S. Bhathal, Norman R. Hughes
Publikováno v:
Journal of clinical pathology. 66(3)
Aim Cholangiocarcinomas display intestinal and pyloric gland metaplasia-cell phenotypes. Those that arise in chronically inflamed (fluke infested) bile ducts more frequently express the intestinal metaplasia-cell phenotype and p53 than sporadic chola
Autor:
Catherine L, Kennedy, Meri, Najdovska, Gareth W, Jones, Louise, McLeod, Norman R, Hughes, Cody, Allison, Chia Huey, Ooi, Patrick, Tan, Richard L, Ferrero, Simon A, Jones, Anouk, Dev, William, Sievert, Prithi S, Bhathal, Brendan J, Jenkins
Publikováno v:
The Journal of pathology. 225(2)
Chronic activation of the gastric mucosal adaptive immune response is a characteristic trait of gastric cancer. It has recently emerged that a new class of T helper (Th) cells, defined by their ability to produce interleukin (IL)-17A (Th17), is assoc
Publikováno v:
The American journal of surgical pathology. 34(9)
The so-called bile duct adenoma and peribiliary glands are characterized by the expression of two foregut antigens (designated D10 and 1F6) and secretion of acid mucin. On account of this similarity in phenotype and their frequent close association w
Autor:
Jane E. Armes, Matthias Ernst, Vance Matthews, Michael Buchert, Brendan J. Jenkins, Dianne Grail, Paul J. Hertzog, Jonathon D. Sedgwick, Meri Najdovska, Prithi S. Bhathal, Songqing Na, Norman R. Hughes, Therese Lundgren-May, Eric G. Marcusson, James G. Karras, Hazel Tye
Publikováno v:
Journal of Clinical Investigation.
Deregulated activation of STAT3 is frequently associated with many human hematological and epithelial malignancies, including gastric cancer. While exaggerated STAT3 signaling facilitates an antiapoptotic, proangiogenic, and proproliferative environm
Autor:
R. C. Newland, Norman R. Hughes
Publikováno v:
The Journal of Pathology. 160:41-50
The histology and immunohistochemistry of 896 polyps and other focal epithelial abnormalities detected macroscopically in 86 surgical resections from patients with colorectal adenocarcinoma and benign bowel disorders were studied. The lesions identif