Výsledky vyhledávání - "Norman L, Oxlade"

Blood profile holds clues to role of infection in a premonitory state for idiopathic parkinsonism and of gastrointestinal infection in established disease

Autor: James Bowthorpe, Clive Weller, Tracy Dew, Andrew J. Lawson, Roy Sherwood, Mohammad A. A. Ibrahim, Andre Charlett, Sylvia M. Dobbs, Alan Curry, Ingvar Bjarnason, Dale W. Peterson, J. Malcolm Plant, R. John Dobbs, Norman L. Oxlade

Publikováno v: Gut Pathogens, Vol 1, Iss 1, p 20 (2009)
Gut Pathogens

The two-stage neuroinflammatory process, containment and progression, proposed to underlie neurodegeneration may predicate on systemic inflammation arising from the gastrointestinal tract.Helicobacterinfection has been described as one switch in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac65440be41bb7a5f464076707ac16c
http://www.gutpathogens.com/content/1/1/20

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Helicobacter hypothesis for idiopathic parkinsonism: before and beyond

Autor: Ingvar Bjarnason, Maria V. McCrossan, Ashley B. Price, Clive Weller, Alan Curry, Malur Sudhanva, Norman L. Oxlade, John O'Donohue, R. John Dobbs, Sylvia M. Dobbs, John Williams, Robert J. Owen, Mohammad A. A. Ibrahim, Jeremy D. Sanderson, David S. Ellis, Andre Charlett

Publikováno v: Helicobacter

We challenge the concept of idiopathic parkinsonism (IP) as inevitably progressive neurodegeneration, proposing a natural history of sequential microbial insults with predisposing host response. Proof‐of‐principle that infection can contribute to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d2ff1c0bff8da72a4a09575f7349af
https://pubmed.ncbi.nlm.nih.gov/19250506

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Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 2: response of facets of clinical idiopathic parkinsonism to Helicobacter pylori eradication. A randomized, double-blind, placebo-controlled efficacy study

Autor: Ingvar T, Bjarnason, Inguar T, Bjarnason, André, Charlett, R John, Dobbs, Sylvia M, Dobbs, Mohammad A A, Ibrahim, Robert W, Kerwin, Robert F, Mahler, Norman L, Oxlade, Dale W, Peterson, J Malcolm, Plant, Ashley B, Price, Clive, Weller

Publikováno v: Helicobacter. 10(4)

BACKGROUND Links between etiology/pathogenesis of neuropsychiatric disease and infection are increasingly recognized. AIM Proof-of-principle that infection contributes to idiopathic parkinsonism. METHODS Randomized, double-blind, placebo-controlled e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294d65842f30dcec2b07cf47fbd32a57
https://pubmed.ncbi.nlm.nih.gov/16104943

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Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 3: predicted probability and gradients of severity of idiopathic parkinsonism based on H. pylori antibody profile

Autor: Sylvia M. Dobbs, Andre Charlett, Norman L. Oxlade, Clive Weller, Dale W. Peterson, R. John Dobbs, Ingvar Bjarnason

Publikováno v: Helicobacter. 10(4)

Background Eradicating Helicobacter may convert rapidly progressive idiopathic parkinsonism to quieter disease, however only a minority of probands have evidence of current infection. Aim To explore the cross-sectional fit of parkinsonism as an extra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275e234481cc19e99a66b0b06313db8a
https://pubmed.ncbi.nlm.nih.gov/16104944

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Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 1: eradication of Helicobacter in the cachexia of idiopathic parkinsonism

Autor: R John, Dobbs, Sylvia M, Dobbs, Clive, Weller, Ingvar T, Bjarnason, Ingua T, Bjarnason, Norman L, Oxlade, André, Charlett, Mazin A, Al-Janabi, Robert W, Kerwin, Robert F, Mahler, Ashley B, Price

Publikováno v: Helicobacter. 10(4)

Background. Links between etiology/pathogenesis of neuropsychiatric disease and infection are increasingly recognized. Aim. Proof-of-principle that infection contributes to idiopathic parkinsonism. Methods. Randomized, double-blind, placebo-controlle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e45919e5572221889e35ab0e132730
https://pubmed.ncbi.nlm.nih.gov/16104942

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Role of inflammation in gastrointestinal tract in aetiology and pathogenesis of idiopathic parkinsonism

Autor: Clive Weller, Ingvar Bjarnason, Sylvia M. Dobbs, Norman L. Oxlade, R. John Dobbs, Andre Charlett

Publikováno v: FEMS immunology and medical microbiology. 44(2)

Idiopathic parkinsonism (IP) is a common disorder, conventionally regarded as neurodegenerative. Its cardinal features, poverty and slowness of movement, muscle rigidity, postural abnormality and a characteristic tremor, are associated with loss of d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d85c36ca5abe7208333e46f1705dc37
https://pubmed.ncbi.nlm.nih.gov/15866206

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