Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Norman J. Uretsky"'
Publikováno v:
Behavioural Brain Research. 114:167-174
We have been studying sensitization of psychostimulant-induced stereotyped behavior in mice using both a context-dependent and a context-independent paradigm. In the present study, we tested whether N-methyl-D-aspartate (NMDA) receptor antagonists pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee33886dcad51df93e0477916d720bc0
https://doi.org/10.1016/s0166-4328(00)00227-8
https://doi.org/10.1016/s0166-4328(00)00227-8
Publikováno v:
Pharmacology Biochemistry and Behavior. 63:263-269
The present study was designed to determine whether the environmental context in which amphetamine is administered plays a role in the development of sensitization to the stereotyped behavioral effects of amphetamine in mice. In male CF-1 mice, the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15ed0adce8e364d1d8f95caaae4cd422
https://doi.org/10.1016/s0091-3057(98)00259-7
https://doi.org/10.1016/s0091-3057(98)00259-7
Publikováno v:
Brain Research. 788:111-117
The hypothesis to be tested was that increased dopaminergic transmission induced by amphetamine in the nucleus accumbens results in increased glutamatergic neurotransmission in this brain area and that the increase in level of this neurotransmitter c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7705335c6b00a833283bbc684388bd7
https://doi.org/10.1016/s0006-8993(97)01518-7
https://doi.org/10.1016/s0006-8993(97)01518-7
Autor:
Guoping Sun, John C. Miller, G. Shams, Lane J. Wallace, Norman J. Uretsky, Meri Slavica, David M. Weinstein, Duane D. Miller
Publikováno v:
Journal of Medicinal Chemistry. 41:1034-1041
The R- and S-isomers of 3,5-dinitro-o-tyrosine (6a,b) have been synthesized through the use of chemoenzymatic synthesis and shown to bind differentially with the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA, 3) receptors. The phenol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e1aa590c72b3cfef4638f26dc7f8b3
https://doi.org/10.1021/jm970276q
https://doi.org/10.1021/jm970276q
Publikováno v:
Neuroscience Letters. 233:5-8
At doses that elicit behavioral activation, apomorphine does not induce Fos-protein in the nucleus accumbens of control animals but does under conditions of denervation supersensitivity. The purpose of this study was to determine whether apomorphine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3cfed4a857da3125cda3bf2f0726161
https://doi.org/10.1016/s0304-3940(97)00615-0
https://doi.org/10.1016/s0304-3940(97)00615-0
Autor:
David L. Willins, Lane J. Wallace, Duane D. Miller, Ronald A. Hill, David M. Weinstein, Satyavijayan Narasimhan Danthi, Norman J. Uretsky, Gamal Shams, Henry Tai, Richard T. Layer
Publikováno v:
Journal of Medicinal Chemistry. 40:3182-3191
Antagonists of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid (AMPA) receptors may have therapeutic potential as psychotropic agents. A series of mononitro- and dinitro-2- and 3-hydroxyphenylalanines was prepared, and their activity compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb34ae54e360dfe0720e7df7ca27426
https://doi.org/10.1021/jm950028z
https://doi.org/10.1021/jm950028z
Publikováno v:
Brain Research. 748:263-266
The locomotor stimulant response to either systemic or intra-accumbens amphetamine was enhanced 1-2 weeks after pre-treatment with pertussis toxin (PTX) into any of 3 different sites in the ventral tegmental area (VTA). An enhanced response to either
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e278e8765b5f9933a88fd46e117d3f
https://doi.org/10.1016/s0006-8993(96)01379-0
https://doi.org/10.1016/s0006-8993(96)01379-0
Publikováno v:
Brain Research Bulletin. 43:435-439
Amphetamine produces an enhanced locomotor stimulatory response in animals injected with pertussis toxin into the ventral tegmental area. This response is dependent on the activation of D1 receptors in the nucleus accumbens. The immediate early gene,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55119c1f31ccc63220d2852e89d69f8
https://doi.org/10.1016/s0361-9230(97)00030-0
https://doi.org/10.1016/s0361-9230(97)00030-0
Publikováno v:
Brain Research. 728:209-214
DNQX, an antagonist of AMPA/kainate receptors, was injected into the ventral tegmental area (VTA) to test the hypothesis that AMPA/kainate receptors in this brain region might be involved in regulation of locomotor activity. Bilateral injection of 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663e8da37de0872d4a38eed892da157e
https://doi.org/10.1016/0006-8993(96)00399-x
https://doi.org/10.1016/0006-8993(96)00399-x
Autor:
Gamal Shams, Guoping Sun, David M. Weinstein, Norman J. Uretsky, Duane D. Miller, Lane J. Wallace
Publikováno v:
Journal of Medicinal Chemistry. 39:4430-4438
Recently discovered 6,7-disubstituted quinoxaline-2,3-diones, 1, have been found to antagonize specific binding and functional responses to both α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) and kainic acid. Although a variety of studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5107efec7b9b4b72dc1a8047c15c7ff4
https://doi.org/10.1021/jm950632+
https://doi.org/10.1021/jm950632+