Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Norman Haughey"'
Autor:
Alison Buchholz, Pragney Deme, Joshua F. Betz, Jason Brandt, Norman Haughey, Mackenzie C. Cervenka
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
BackgroundAlzheimer’s disease (AD) is increasing in prevalence, but effective treatments for its cognitive impairment remain severely limited. This study investigates the impact of ketone body production through dietary manipulation on memory in pe
Externí odkaz:
https://doaj.org/article/1a50f27764e3440d98c342ae8e070478
Autor:
Alex M. Dickens, Tory P. Johnson, Santosh Lamichhane, Anupama Kumar, Carlos A. Pardo, Erie G. Gutierrez, Norman Haughey, Mackenzie C. Cervenka
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: This study aims to test the hypothesis that increased ketone body production resulting from a ketogenic diet (KD) will correlate with reductions in pro-inflammatory cytokines and lipid subspecies and improved clinical outcomes in adults
Externí odkaz:
https://doaj.org/article/32b26ad926d34d81b35d2df2791b6aab
Autor:
Benjamin J. Bell, Kristen R. Hollinger, Pragney Deme, Shinji Sakamoto, Yuto Hasegawa, David Volsky, Atsushi Kamiya, Norman Haughey, Xiaolei Zhu, Barbara S. Slusher
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 23, Iss , Pp 100478- (2022)
Combined antiretroviral therapy ushered an era of survivable HIV infection in which people living with HIV (PLH) conduct normal life activities and enjoy measurably extended lifespans. However, despite viral control, PLH often experience a variety of
Externí odkaz:
https://doaj.org/article/0850c2e7117c4dc59e642809a5571c0e
Autor:
Lubriel Sambolín-Escobales, Lizmarie Tirado-Castro, Cristina Suarez, Dariangelly Pacheco-Cruz, Wilfred Fonseca-Ferrer, Pragney Deme, Norman Haughey, Gladys Chompre, James T. Porter
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Clinical and preclinical studies suggest that increases in long-chain ceramides in blood may contribute to the development of depressive-like behavior. However, which factors contribute to these increases and whether the increases are sufficient to i
Externí odkaz:
https://doaj.org/article/5a193a174dcf422188ccb5c3e2f31b6c
Autor:
Arens Taga, Raha Dastgheyb, Christa Habela, Jessica Joseph, Jean‐Philippe Richard, Sarah K. Gross, Giuseppe Lauria, Gabsang Lee, Norman Haughey, Nicholas J. Maragakis
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 12, Pp 1272-1285 (2019)
Abstract The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for modeling central nervous system biology in vitro. We describe a unique method
Externí odkaz:
https://doaj.org/article/90f3a373826542afa217b6c5c8f992af
Autor:
Haojun Yang, Martina Ralle, Michael J Wolfgang, Neha Dhawan, Jason L Burkhead, Susana Rodriguez, Jack H Kaplan, G William Wong, Norman Haughey, Svetlana Lutsenko
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2006519 (2018)
Copper (Cu) has emerged as an important modifier of body lipid metabolism. However, how Cu contributes to the physiology of fat cells remains largely unknown. We found that adipocytes require Cu to establish a balance between main metabolic fuels. Di
Externí odkaz:
https://doaj.org/article/f6306c1815e54a438c192f951701973e
Autor:
Guoku Hu, Kenneth W. Witwer, Vincent C. Bond, Norman Haughey, Fatah Kashanchi, Lynn Pulliam, Shilpa Buch
Publikováno v:
Journal of Extracellular Vesicles, Vol 6, Iss 1 (2017)
Extracellular vesicles (EVs) are globular, membrane bound nanovesicles (30–100 nm range) that are shed both during normal cellular functioning and under pathological conditions by most cell types. In recent years, there has been significant interes
Externí odkaz:
https://doaj.org/article/48aaf18272e34d788ec0f54a62a2fcf0
Autor:
Myoung-Hwa Lee, Tongguang Wang, Mi-Hyeon Jang, Joseph Steiner, Norman Haughey, Guo-li Ming, Hongjun Song, Avindra Nath, Arun Venkatesan
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 3, Pp 678-687 (2011)
The prevalence of central nervous system (CNS) neurologic dysfunction associated with human immunodeficiency virus (HIV) infection continues to increase, despite the use of antiretroviral therapy. Previous work has focused on the deleterious effects
Externí odkaz:
https://doaj.org/article/0b55c3b9b2c64276bcb09f2a0f5de718
Autor:
Jadwiga Turchan-Cholewo, Yiling Liu, Suzanne Gartner, Rollie Reid, Chunfa Jie, Xuejun Peng, Kuey Chu C. Chen, Ashok Chauhan, Norman Haughey, Roy Cutler, Mark P. Mattson, Carlos Pardo, Katherine Conant, Ned Sacktor, Justin C. McArthur, Kurt F. Hauser, Chandra Gairola, Avindra Nath
Publikováno v:
Neurobiology of Disease, Vol 23, Iss 1, Pp 109-119 (2006)
Human immunodeficiency virus (HIV) infection continues to rise in drug-abusing populations and causes a dementing illness in a subset of individuals. Factors contributing to the development of dementia in this population remain unknown. We found that
Externí odkaz:
https://doaj.org/article/71edcae4f2f1487db7e2a562e0917ae4
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 2-19 (2002)
Mutations in presenilin-1 (PS1) can cause early onset familial Alzheimer's disease (AD). Studies of cultured cells and mice expressing mutant PS1 suggest that PS1 mutations may promote neuronal dysfunction and degeneration by altering cellular calciu
Externí odkaz:
https://doaj.org/article/1ce97aee43e04d2eb769e1ae10716cd5