Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Norman H. Rogers"'
Publikováno v:
ChemInform. 21
Publikováno v:
ChemInform. 21
The preparation of a large variety of normonyl heterocycles is described. Methods involving cyclisation of monic acid derivatives gave access to only a limited number of types of heterocycles. Olefination methods proved to be of wider applicability w
Publikováno v:
Tetrahedron. 43:3295-3302
The preparation of a series of 2-(heterocyclyl)-4-ethyl-4,7-dihydro -7-oxothieno[3,2-b]pyridine-6-carboxylic acids (5j-1) by aminolysis of the corresponding 2-bromo derivative (5i) is described. None of the compounds (5j-1) showed any interesting ant
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :729-734
Routes to the preparation of αβ-unsaturated ketones (1k–m) have been investigated. n-Butylmanganese(II) chloride was particularly useful for preparing the ketones (1m) from the readily available monic acid A (1b), the nucleus of pseudomonic acid
Publikováno v:
Tetrahedron Letters. 21:881-884
A new antibiotic, pseudomonic acid C (2a), has been isolated from fermentations of the strain of Pseudomonas fluorescens which produces the known and structurally similar antibiotics pseudomonic acids A (1a) and B (1c).
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2059-2063
A number of mild methods for the preparation of 2-substituted 5-normonyloxazoles (1) by dehydrative cyclisation of the corresponding monamides (2) have been developed and are described. The preferred conditions involve using trichloroacetyl chloride,
Publikováno v:
Tetrahedron. 43:2165-2175
The preparations of methyl 13-deoxypseudomonate (2c) and methyl (13R)-monate (4f) via mesylate derivatives are described. Introduction of an amino function by nucleophilic displacement at the C-13 position was unsuccessful but the 13-amine (2f) was p
Autor:
Peter Charles Thomas Hannan, Rhona Mary Banks, Norman H. Rogers, Peter J. O'hanlon, Ann C. Donald
Publikováno v:
The Journal of Antibiotics. 41:609-613
The antimycoplasmal activities of the pseudomonic acids isolated from Pseudomonas fluorescens NCIB 10586 are reported. Structure-activity relationships of a variety of ester, amide and thiol ester derivatives of the nucleus, monic acid A, are describ
Autor:
Norman H. Rogers
Publikováno v:
Health Education Journal. 14:208-214
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :561
The configuration of the double bond in pseudomonic acid A (1a) is shown to be E by comparison of the spectroscopic properties of its methyl ester (1b) with those of methyl isopseudomonate A (2) obtained from (1b) by photolysis. Ozonolysis of methyl