Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Norman F Gaudette"'
Publikováno v:
Chemical Research in Toxicology
The observed toxicity and carcinogenicity of 1,3-dichloro-2-propanol (DCP) in rodents is thought to be due to the formation of reactive metabolites, epichlorohydrin (ECH) and dichloroacetone (DCA). However, there is no direct evidence for the formati
Publikováno v:
Toxicology letters. 178(1)
Styrene-acrylonitrile trimer (SAN Trimer), a mixture of six isomers (four isomers of 4-cyano-1,2,3,4-tetrahydro-alpha-methyl-1-naphthaleneacetonitrile [THAN] and two isomers of 4-cyano-1,2,3,4-tetrahydro-1-naphthaleneproprionitrile [THNP]), is a by-p
Autor:
Norman F. Gaudette, Jon W. Lodge
Publikováno v:
Journal of analytical toxicology. 29(1)
A liquid chromatographic method for the determination of methylene blue and leucomethylene blue in male and female Fischer 344 rat urine and male and female B6C3F1 mouse urine was developed for use in supporting toxicokinetic studies, validated, and
Autor:
James Fossett, Norman F. Gaudette, A Jeffcoat, AP Stanley, Kelly J. Dix, Donna P. Coleman, Brian F. Thomas
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 31(6)
1. The disposition of propargyl alcohol (PAL) radiolabelled with carbon-14 ([2,3-14C]PAL) was determined in the F344 rat and B6C3F1 mouse following intravenous (i.v.), oral, inhalation and dermal exposure. 2. By 72h following an i.v. (1 mg kg(-1) or