Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Norman D. Weiner"'
Publikováno v:
Journal of Lipid Research, Vol 12, Iss 2, Pp 155-159 (1971)
The π-A characteristics of seven known oxidation products of cholesterol were determined. In all cases, the oxidation products yielded films which were more expanded than the film of cholesterol. Shifts in the position of the functional polar groups
Externí odkaz:
https://doaj.org/article/b262410f45ca4934b8d3f3e0ea59d73c
Publikováno v:
Journal of Lipid Research, Vol 13, Iss 2, Pp 253-255 (1972)
The autoxidative formation of 7-ketocholesterol and diols from aqueous cholesterol dispersions and from cholesterol monomolecular films has been studied as a function of time. The rate of oxidation of cholesterol is much faster at the surface than in
Externí odkaz:
https://doaj.org/article/7dcab11657ae4feabd530b3aa63f45f3
Autor:
Norman D. Weiner, Alvin Felmeister
Publikováno v:
Journal of Lipid Research, Vol 11, Iss 3, Pp 220-222 (1970)
The apparent condensation effect observed with mixed monolayers of lecithin and cholesterol has been examined with respect to both molecular interaction and molecular cavity models. For each, model equations are presented which predict the surface ar
Externí odkaz:
https://doaj.org/article/5faf1647471446abaaf92634eba2f0bd
Autor:
Peter Lockwood, Norman D. Weiner, Sheree E. Cross, Michael S. Roberts, Jeffrey E. Grice, Susan Ciotti
Publikováno v:
Journal of Pharmaceutical Sciences. 99:712-718
We examined uptake of the model therapeutic agent, minoxidil, into appendages, stratum corneum (SC), and through human skin, under the influence of different vehicles. Quantitative estimation of therapeutic drug deposition into all three areas has no
Autor:
Kristen Kingzett, Norman D. Weiner, Anna U. Bielinska, Huailiang Wu, Chandrasekharan Ramachandran, Rong Sun, Blake J. Roessler
Publikováno v:
International Journal of Pharmaceutics. 221:23-34
Expression plasmids encoding chloramphenicol acetyltransferase (CAT) or human interferon-alpha2 cDNA were formulated in water-in-oil nanoemulsions and applied to murine skin. The histological location of transfected cells was assessed by in situ DNA
Publikováno v:
Journal of Liposome Research. 9:129-138
Our previous reports using hairless mouse skin model showed that topical delivery of cyclosporin-A (CsA) could be achieved and controlled with nonionic liposomal and nonionic lipid-based formulations composed of glyceryl dilaurate (GDL), cholesterol
Publikováno v:
Journal of Liposome Research. 9:139-153
In an earlier report (1) we described the controlled follicular delivery of hydrophobic macromolecules from nonionic lipid-based formulations composed of glyceryl dilaurate (GDL), cholesterol (CH), and polyoxyethylene-10-stearyl ether (POE-10). Howev
Autor:
Norman D. Weiner
Publikováno v:
International Journal of Pharmaceutics. 162:29-38
The hair follicle, hair shaft and sebaceous gland collectively form what is recognized as the pilosebaceous unit. This complex, 3-D structure within the skin, possesses a unique biochemistry, metabolism and immunology. Recent studies have focused on
Publikováno v:
Journal of Liposome Research. 8:225-238
In a previous report (1), we showed that the rate and extent of uptake of cyclosporin-A (CsA) following topical application of nonionic liposomal formulations composed of glyceryl dilaurate (GDL), cholesterol (CH), and polyoxyethylene-10-stearyl ethe
Autor:
Blake J. Roessler, Norman D. Weiner, Jill M. Latta, Chandrasekharan Ramachandran, S. M. Niemiec
Publikováno v:
Journal of Pharmaceutical Sciences. 86:701-708
Expression plasmid DNA for the human interleukin-1 receptor antagonist (IL-1ra) protein was formulated with nonionic:cationic (NC) liposomes or phosphatidylcholine:cationic (PC) liposomes and applied to the auricular skin of hamsters in single- and m