Zobrazeno 1 - 10 of 56 pro vyhledávání: '"Norman Chan"'
1
Data Supplement from Hypoxia Provokes Base Excision Repair Changes and a Repair-Deficient, Mutator Phenotype in Colorectal Cancer Cells
Autor: Robert G. Bristow, Steven Gallinger, Peter G. Wells, Bradly G. Wouters, Marianne Koritzinsky, Ramya Kumareswaran, Gordon P. McCallum, Mohsin Ali, Norman Chan
Supplementary Figure 1. (A) There is no effect on cell proliferation in RKO cells. (B) There is no effect on S-phase fraction in RKO and paired HCT116 cells. (C) 50-65% Clonogenic cell survival in RKO and paired HCT116 cells. (D) BER mRNA expression
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fbb0cee1bc5886b867a3bc299ab747
https://doi.org/10.1158/1541-7786.22513990.v1
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3
Data from PTEN Deletion in Prostate Cancer Cells Does Not Associate with Loss of RAD51 Function: Implications for Radiotherapy and Chemotherapy
Autor: Robert G. Bristow, Thomas Helleday, Andrew Evans, Tarek A. Bismar, Anthony M. Joshua, Norman Chan, Carla Coackley, Cecilia Lundin, Kaisa R. Luoto, Helen Zhao, Michael Fraser
Purpose:PTEN deletions in prostate cancer are associated with tumor aggression and poor outcome. Recent studies have implicated PTEN as a determinant of homologous recombination (HR) through defective RAD51 function. Similar to BRCA1/2-defective tumo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655152a4aa9bea9e8a3a0acf534a76a6
https://doi.org/10.1158/1078-0432.c.6520059.v1
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