Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Norman B. Roberts"'
Autor:
Brendan P. Norman, Andrew S. Davison, Juliette H. Hughes, Hazel Sutherland, Peter JM. Wilson, Neil G. Berry, Andrew T. Hughes, Anna M. Milan, Jonathan C. Jarvis, Norman B. Roberts, Lakshminarayan R. Ranganath, George Bou-Gharios, James A. Gallagher
Publikováno v:
Genes and Diseases, Vol 9, Iss 4, Pp 1129-1142 (2022)
Alkaptonuria (AKU) is an inherited disorder of tyrosine metabolism caused by lack of active enzyme homogentisate 1,2-dioxygenase (HGD). The primary consequence of HGD deficiency is increased circulating homogentisic acid (HGA), the main agent in the
Externí odkaz:
https://doaj.org/article/957bdcfaa6bb4d9d97d9bf338e2f3358
Autor:
Brendan P. Norman, Andrew S. Davison, Bryony Hickton, Gordon A. Ross, Anna M. Milan, Andrew T. Hughes, Peter J. M. Wilson, Hazel Sutherland, Juliette H. Hughes, Norman B. Roberts, George Bou-Gharios, James A. Gallagher, Lakshminarayan R. Ranganath
Publikováno v:
Metabolites, Vol 12, Iss 10, p 927 (2022)
Metabolomic analyses in alkaptonuria (AKU) have recently revealed alternative pathways in phenylalanine-tyrosine (phe-tyr) metabolism from biotransformation of homogentisic acid (HGA), the active molecule in this disease. The aim of this research was
Externí odkaz:
https://doaj.org/article/e39b7f67a9a743138b22b940540aaf21
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 80:630-639
The assay in serum of non-caeruloplasmin copper, as exchangeable copper after complexation with EDTA (ExCu) and total copper has been evaluated and compared in patients with varying c-reactive protein(CRP). Measurement of ExCu and total copper, range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec225a27b19dab092a7509ee55ecddc
https://doi.org/10.1080/00365513.2020.1821397
https://doi.org/10.1080/00365513.2020.1821397
Autor:
Robert Bittl, Hartmut Oschkinat, Christian Teutloff, Norman B. Roberts, Brendan P. Norman, Wing Ying Chow, Melinda J. Duer, Lakshminarayan R. Ranganath, James A. Gallagher
Publikováno v:
Angewandte Chemie. 132:12035-12040
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b6d2801500e8d342b13c7d887ae3b99
https://doi.org/10.1002/ange.202000618
https://doi.org/10.1002/ange.202000618
Autor:
Birgitta Olsson, James A. Gallagher, S.L. Curtis, Anna M. Milan, Brendan P. Norman, Norman B. Roberts, Lakshminarayan R. Ranganath
Publikováno v:
CLINICAL BIOCHEMISTRY
Objectives We have assessed the effect of elevated concentrations of hydroxyphenylpyruvic acid (HPPA), hydroxyphenyllactic acid (HPLA) and tyrosine, on a range of chemistry tests in serum and urine to explore the potential for chemical interference o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bbfcc97580a95bdd2864340cde9abe
https://doi.org/10.1016/j.clinbiochem.2019.06.010
https://doi.org/10.1016/j.clinbiochem.2019.06.010
Autor:
Andrew S. Davison, Andrew T. Hughes, James A. Gallagher, Gordon A. Ross, Norman B. Roberts, Brendan P. Norman, Jonathan C. Jarvis, Anna M. Milan, Hazel Sutherland, Lakshminarayan R. Ranganath
Publikováno v:
Clinical chemistry
BACKGROUND Identification of unknown chemical entities is a major challenge in metabolomics. To address this challenge, we developed a comprehensive targeted profiling strategy, combining 3 complementary liquid chromatography quadrupole time-of-fligh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32644627d9ad58809d94a0c1380d71d9
https://doi.org/10.1373/clinchem.2018.295345
https://doi.org/10.1373/clinchem.2018.295345
Autor:
Lakshminarayan R. Ranganath, James A. Gallagher, Robert Bittl, Christian Teutloff, Melinda J. Duer, Hartmut Oschkinat, Brendan P. Norman, Wing Ying Chow, Norman B. Roberts
Publikováno v:
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Angewandte Chemie (International ed. in English)
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English)
Angewandte Chemie (International Ed. in English)
Alkaptonuria (AKU) is a rare disease characterized by high levels of homogentisic acid (HGA); patients suffer from tissue ochronosis: dark brown pigmentation, especially of joint cartilage, leading to severe early osteoarthropathy. No molecular mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d043f32465552a8693b36a5fccde1c72
http://livrepository.liverpool.ac.uk/3081396/3/BlackCartilageDNP_manuscript-edit_20200324.pdf
http://livrepository.liverpool.ac.uk/3081396/3/BlackCartilageDNP_manuscript-edit_20200324.pdf
Autor:
Wing Ying Chow, Christian Teutloff, Norman B. Roberts, James A. Gallagher, Robert Bittl, Lakshminarayan R. Ranganath, Brendan P. Norman, Melinda J. Duer, Hartmut Oschkinat
Publikováno v:
Angewandte Chemie. 132:11770-11770
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124203c60630ddd52735efb9c9b0c858
https://doi.org/10.1002/ange.202005824
https://doi.org/10.1002/ange.202005824
Autor:
Robert Bittl, Hartmut Oschkinat, Wing Ying Chow, Norman B. Roberts, Lakshminarayan R. Ranganath, James A. Gallagher, Christian Teutloff, Brendan P. Norman, Melinda J. Duer
Publikováno v:
Angewandte Chemie International Edition. 59:11674-11674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4810d251e9b73ac2ba60ea1f05247d8e
https://doi.org/10.1002/anie.202005824
https://doi.org/10.1002/anie.202005824
Autor:
Sobhan Vinjamuri, L.F. Taylor, Norman B. Roberts, Anna M. Milan, Gordon A. Ross, Lakshminarayan R. Ranganath, Andrew S. Davison, James A. Gallagher, Brendan P. Norman
Publikováno v:
OSTEOARTHRITIS AND CARTILAGE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ff9c7fe63ae1ee5427bfaec0797447